Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Michael E. Coleman"'
Autor:
Hongyan Lu, Stephanie Merfeld-Clauss, Yameena Jawed, Keith L. March, Michael E. Coleman, Natalia V. Bogatcheva
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
We have shown previously that adipose stromal cell (ASC)-derived conditioned media (CM) limited lung injury, endothelial barrier dysfunction, and apoptosis. Here, we used endothelial hyperpermeability and apoptosis assays to investigate how concentra
Externí odkaz:
https://doaj.org/article/deb7baf100c04313950ce5aaee2f8b75
Concentrated Secretome of Adipose Stromal Cells Limits Influenza A Virus-Induced Lung Injury in Mice
Publikováno v:
Cells, Vol 10, Iss 4, p 720 (2021)
Despite vaccination and antivirals, influenza remains a communicable disease of high burden, with limited therapeutic options available to patients that develop complications. Here, we report the development and preclinical characterization of Adipos
Externí odkaz:
https://doaj.org/article/d15217308b84466a8ea0a8f9935cc715
Publikováno v:
Biochemistry. Biokhimiia. 84(11)
Mesenchymal stromal cell (MSCs) represent a class of biologics with the prospects for employment as immunomodulatory, tissue-protective, and regenerative therapeutics. In parallel with cellular therapy, cell-free therapy based on MSC-secreted bioacti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::114d36bf0af3620412ac77640ead97cf
https://pubmed.ncbi.nlm.nih.gov/31760924
https://pubmed.ncbi.nlm.nih.gov/31760924
Autor:
Robert J. Wall, Vernon G. Pursel, Kevin D. Wells, Michael E. Coleman, Giuseppe Bee, Morse B. Solomon, Robert J. Schwartz, A. D. Mitchell, Kimiaki Maruyama
Research was conducted to determine if directing expression of insulin-like growth factor I (IGF1) specifically to striated muscle would enhance lean muscle growth in swine. At 120 kg BW, 25 transgenic (T) and 26 control (C) pigs were sacrificed to e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46b764feaf6cd72eee93fb32bce261c1
https://www.arch-anim-breed.net/50/501/2007/
https://www.arch-anim-breed.net/50/501/2007/
Autor:
Jennifer Rutering, Alejandro Recio, Matthias Ilmer, Jody Vykoukal, Michael E. Coleman, Eckhard Alt
Publikováno v:
Journal of stem cell research & therapy
Cell therapy represents a promising new paradigm for treatment of heart disease, a major cause of death in the industrialized world. The recent discovery of tissue resident c-Kit+ cardiac progenitor cells (CPCs) has fueled scientific efforts to explo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8fb9610c88a2c735fe58ebbe548b0c5
https://pubmed.ncbi.nlm.nih.gov/26937295
https://pubmed.ncbi.nlm.nih.gov/26937295
Autor:
Xiaowen Bai, Roxana Metzele, Zhizhong Z. Pan, Christopher Alt, Zhi Zhang, Jody Vykoukal, Yasheng Yan, Yao-Hua Song, Eckhard Alt, Michael E. Coleman
Publikováno v:
The FASEB Journal. 25:830-839
Various types of stem cells have been shown to have beneficial effects on cardiac function. It is still debated whether fusion of injected stem cells with local resident cardiomyocytes is one of the mechanisms. To better understand the role of fusion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18a86ed013b4e9f76dace6c5578560c9
https://doi.org/10.1096/fj.09-153221
https://doi.org/10.1096/fj.09-153221
Autor:
Parwis Fotuhi, Nadine Matthias, Kai Pinkernell, Eckhard Alt, Mandy Scharlau, Michael E. Coleman, Christoph S. Nabzdyk, Yao-Hua Song, Sebastian Gehmert
Publikováno v:
International Journal of Cardiology. 144:26-35
The aim of this study was to investigate the effect of intracoronary administration of freshly isolated, uncultured autologous tissue-derived stromal cells on cardiac function and perfusion after acute infarction in pigs.A transmural myocardial infar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9849f4c9fc78d189ab0cdd7711024b89
https://doi.org/10.1016/j.ijcard.2009.03.124
https://doi.org/10.1016/j.ijcard.2009.03.124
Autor:
Giulio Pompilio, Adriana Visonà, M.G. Wyatt, Iris Baumgartner, Sigrid Nikol, Emmanuel Pham, Melissa Fusari, Curt Diehm, Dominique Stephan, François Meyer, Eric Van Belle, Lasantha Dinesh Wijesinghe, Maurizio C. Capogrossi, Joseph Emmerich, Nicole Ferreira-Maldent, Michael E. Coleman, Augusto F. Gallino, Vincent Grek, Frank Vermassen
Publikováno v:
Molecular Therapy. 16(5):972-978
This study evaluated the efficacy and safety of intramuscular administration of NV1FGF, a plasmid-based angiogenic gene delivery system for local expression of fibroblast growth factor 1 (FGF-1), versus placebo, in patients with critical limb ischemi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd003a0c4e82ba95ec9f39f1ee279d58
Publikováno v:
The Laryngoscope. 114:368-371
Objectives/Hypothesis: To determine whether the myotrophic activity of human insulin-like growth factor (hIGF)-1 promotes restoration of normal myosin heavy chain (MHC) composition after nerve injury, MHC composition was analyzed after hIGF-1 gene tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eb2bebf212b4d3b8cb4c91cae7670e8
https://doi.org/10.1097/00005537-200402000-00035
https://doi.org/10.1097/00005537-200402000-00035
Autor:
Timo Z, Nazari-Shafti, Ivone G, Bruno, Rudy F, Martinez, Michael E, Coleman, Eckhard U, Alt, Scott R, McClure
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1235
Umbilical cord is an abundant source of perinatal, plastic adherent mesenchymal stem cells (UC-MSCs). UC-MSCs exhibit robust stemness and strong immunosuppressive and regenerative effects in vivo. This protocol describes enzymatic and mechanical diss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fd923493907d5ea81cb29834bcdf9a62
https://pubmed.ncbi.nlm.nih.gov/25388392
https://pubmed.ncbi.nlm.nih.gov/25388392