Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Michael E Widlansky"'
Autor:
Michael E Widlansky, David M Jensen, Jingli Wang, Yong Liu, Aron M Geurts, Alison J Kriegel, Pengyuan Liu, Rong Ying, Guangyuan Zhang, Marc Casati, Chen Chu, Mobin Malik, Amberly Branum, Michael J Tanner, Sudhi Tyagi, Kristie Usa, Mingyu Liang
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 3, Pp n/a-n/a (2018)
Abstract We investigated the role of microRNAs (miRNA) in endothelial dysfunction in the setting of cardiometabolic disorders represented by type 2 diabetes mellitus (T2DM). miR‐29 was dysregulated in resistance arterioles obtained by biopsy in T2D
Externí odkaz:
https://doaj.org/article/952f272fb18645b9b1998da60a033318
Autor:
Michelle L. Roberts, Justin Westhoff, Jingli Wang, Rong Ying, Susanne M. Cabrera, Michael E. Widlansky
Publikováno v:
JVS - Vascular Science, Vol 4, Iss , Pp 100168- (2023)
Externí odkaz:
https://doaj.org/article/ec40eef026fd4e0992c1e30dac856345
Autor:
Kamila Somayaji, Mogen Frenkel, Luai Tabaza, Alexis Visotcky, Tanya Kruse Ruck, Ernest Kwesi Ofori, Michael E. Widlansky, Jacquelyn Kulinski
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundSinging is a physical activity involving components of the vagal nerves manifested as changes in cardiac autonomic regulation.AimsThe aim of this pilot study is to investigate the acute effects of singing on biomarkers of cardiovascular hea
Externí odkaz:
https://doaj.org/article/3f2b3cc3c7514ec286735192cb337ba9
Autor:
Venkata K. Puppala, Benjamin C. Hofeld, Amberly Anger, Sudhi Tyagi, Scott J. Strath, Judith Fox, Marcie G. Berger, Kwang Woo Ahn, Michael E. Widlansky
Publikováno v:
BMC Geriatrics, Vol 20, Iss 1, Pp 1-11 (2020)
Abstract Background In patients with permanent pacemakers (PPM), physical activity (PA) can be monitored using embedded accelerometers to measure pacemaker detected active hours (PDAH), a strong predictor of mortality. We examined the impact of a PA
Externí odkaz:
https://doaj.org/article/943d590c50bf482ca0adac584cad87a0
Autor:
Mamatha Kakarla, Venkata K. Puppala, Sudhi Tyagi, Amberly Anger, Kathryn Repp, Jingli Wang, Rong Ying, Michael E. Widlansky
Publikováno v:
Cardiovascular Diabetology, Vol 18, Iss 1, Pp 1-11 (2019)
Abstract Background Excessive reactive oxygen species from endothelial mitochondria in type 2 diabetes individuals (T2DM) may occur through multiple related mechanisms, including production of mitochondrial reactive oxygen species (mtROS), inner mito
Externí odkaz:
https://doaj.org/article/dfd4ba76cce04178a547e91a404aeabe
Autor:
Gopika SenthilKumar, Boran Katunaric, Henry Bordas-Murphy, Micaela Young, Erin L. Doren, Mary E. Schulz, Michael E. Widlansky, Julie K. Freed
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 324:H330-H337
Despite data showing that estrogen is vasculoprotective in large conduit arteries, hormone therapy (HT) during menopause has not proven to mitigate cardiovascular disease (CVD) risk. Estrogen exposure through prolonged oral contraceptive use and gend
Autor:
David M. Jensen, Peng Han, Lingegowda S. Mangala, Gabriel Lopez-Berestein, Anil K. Sood, Jing Liu, Alison J. Kriegel, Kristie Usa, Michael E. Widlansky, Mingyu Liang
Publikováno v:
Molecular Therapy. 30:3462-3476
MicroRNA miR-29 promotes endothelial function in human arterioles in part by targeting LYPLA1 and increasing nitric oxide production. In addition, miR-29 is a master inhibitor of extracellular matrix gene expression, which may attenuate fibrosis but
Autor:
Hong Xue, Guangyuan Zhang, Aron M. Geurts, Kristie Usa, David M. Jensen, Yong Liu, Michael E. Widlansky, Mingyu Liang
Publikováno v:
EBioMedicine, Vol 35, Iss , Pp 260-269 (2018)
Background: miR-29 is a master regulator of extracellular matrix genes, but conflicting data on its anti-fibrotic effect have been reported. miR-29 improves nitric oxide (NO) production in arterioles by targeting Lypla1. Mir29b1 targeted mutation exa
Externí odkaz:
https://doaj.org/article/2b19ce4c4c1b46209d1dfb0bacf20622
Autor:
Michael Aljadah, Michael E. Widlansky
Publikováno v:
Circulation Research. 132:182-184
Autor:
Nicholas Sommers, Marcie Berger, Jason C. Rubenstein, James Roth, Amy Pan, Colton Thompson, Michael E. Widlansky
Publikováno v:
European Review of Aging and Physical Activity. 19
Background Physical inactivity and sedentary behavior are modifiable risk factors for chronic disease and all-cause mortality that may have been negatively impacted by the COVID-19 shutdowns. Methods Accelerometry data was retrospectively collected f