Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Michael E Werner"'
Autor:
Keith Pratz, Courtney Dinardo, Martha L Arellano, Michael Thirman, Vinod Pullarkat, Pamela S. Becker, B. Douglas Smith, Meng Zhang, Michael E Werner, Jalaja Potluri, Daniel A. Pollyea
Publikováno v:
HemaSphere, Vol 7, p e68978fe (2023)
Externí odkaz:
https://doaj.org/article/9d932cfaecc64a378a4df2ef7714d55c
Autor:
Kimberly M. Jaffe, Daniel T. Grimes, Jodi Schottenfeld-Roames, Michael E. Werner, Tse-Shuen J. Ku, Sun K. Kim, Jose L. Pelliccia, Nicholas F.C. Morante, Brian J. Mitchell, Rebecca D. Burdine
Publikováno v:
Cell Reports, Vol 14, Iss 8, Pp 1841-1849 (2016)
Cilia are microtubule-based projections that function in the movement of extracellular fluid. This requires cilia to be: (1) motile and driven by dynein complexes and (2) correctly polarized on the surface of cells, which requires planar cell polarit
Externí odkaz:
https://doaj.org/article/6492440964db4e188eb355556e19b34b
Autor:
Kelvin K. Tsai, Shenq-Shyang Huang, Jason J. Northey, Wen-Ying Liao, Chung-Chi Hsu, Li-Hsin Cheng, Michael E. Werner, Chih-Pin Chuu, Chandrima Chatterjee, Jonathon N. Lakins, Valerie M. Weaver
Publikováno v:
Nature cancer, vol 3, iss 6
Resistance to antitumor treatment contributes to patient mortality. Functional proteomic screening of organoids derived from chemotherapy-treated patients with breast cancer identified nuclear receptor corepressor 2 (NCOR2) histone deacetylase as an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6ffd4ae59aba35ebb6ba5ea2a63e7e9
https://escholarship.org/uc/item/2b76h4b8
https://escholarship.org/uc/item/2b76h4b8
Autor:
Michael E. Werner, Troy D. Rogers, Eva J. Brotslaw, Barbara R. Grubb, Maimoona A. Zariwala, Brian J. Mitchell, Michael R. Knowles, Corey M. Jania, Serge Amselem, Marie Legendre, Estelle Escudier, Ximena M. Bustamante-Marin, Patrick R. Sears, Lucie Thomas, L. Réfabert, Wei Ning Yin, Kirby L. Zeman, Laura E. Herring, Lawrence E. Ostrowski
Publikováno v:
American Journal of Human Genetics
American Journal of Human Genetics, 2019, 104 (2), pp.229-245. ⟨10.1016/j.ajhg.2018.12.009⟩
American Journal of Human Genetics, 2019, 104 (2), pp.229-245. ⟨10.1016/j.ajhg.2018.12.009⟩
International audience; Primary ciliary dyskinesia (PCD) is a genetic disorder in which impaired ciliary function leads to chronic airway disease. Exome sequencing of a PCD subject identified an apparent homozygous frameshift variant, c.887_890delTAA
Autor:
Anusha Doshi, Michel Labouesse, Kathryn Rehain-Bell, Amy Shaub Maddox, Adam Sattler, Daniel B. Cortes, Michael E. Werner, Thanh Tk Vuong-Brender
Publikováno v:
Molecular Biology of the Cell
Molecular Biology of the Cell, American Society for Cell Biology, 2020, 31 (15), pp.1623-1636. ⟨10.1091/mbc.E20-05-0304⟩
Molecular Biology of the Cell, American Society for Cell Biology, 2020, 31 (15), pp.1551-1649. ⟨10.1091/mbc.E20-05-0304⟩
Molecular Biology of the Cell, American Society for Cell Biology, 2020, 31 (15), pp.1623-1636. ⟨10.1091/mbc.E20-05-0304)⟩
Molecular Biology of the Cell, 2020, 31 (15), pp.1551-1649. ⟨10.1091/mbc.E20-05-0304⟩
Molecular Biology of the Cell, American Society for Cell Biology, 2020, 31 (15), pp.1623-1636. ⟨10.1091/mbc.E20-05-0304⟩
Molecular Biology of the Cell, American Society for Cell Biology, 2020, 31 (15), pp.1551-1649. ⟨10.1091/mbc.E20-05-0304⟩
Molecular Biology of the Cell, American Society for Cell Biology, 2020, 31 (15), pp.1623-1636. ⟨10.1091/mbc.E20-05-0304)⟩
Molecular Biology of the Cell, 2020, 31 (15), pp.1551-1649. ⟨10.1091/mbc.E20-05-0304⟩
Actomyosin cortical contractility drives many cell shape changes including cytokinetic furrowing. While positive regulation of contractility is well characterized, counterbalancing negative regulation and mechanical brakes are less well understood. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ee5706a97c7d8cc66f85f018d117def
https://hal.archives-ouvertes.fr/hal-03432669
https://hal.archives-ouvertes.fr/hal-03432669
Autor:
Kelvin K, Tsai, Shenq-Shyang, Huang, Jason J, Northey, Wen-Ying, Liao, Chung-Chi, Hsu, Li-Hsin, Cheng, Michael E, Werner, Chih-Pin, Chuu, Chandrima, Chatterjee, Jonathon N, Lakins, Valerie M, Weaver
Publikováno v:
Nature cancer. 3(6)
Resistance to antitumor treatment contributes to patient mortality. Functional proteomic screening of organoids derived from chemotherapy-treated patients with breast cancer identified nuclear receptor corepressor 2 (NCOR2) histone deacetylase as an
Autor:
Joseph M. Caster, Longzhen Zhang, Michael E. Werner, Haydee Lara, Henry P. Foote, Xi Tian, Laura E. Herring, Lola M. Reid, Samuel B. Warner, Kyle C. Roche, Eliane Wauthier, Ariel Dawn Hanson, Andrew Andrew Wang, Jonathan Copp, Stephanie K. Yu, Joel E. Tepper, David S. Hsu, Tian Zhang
Publikováno v:
Nature biomedical engineering
Metastatic disease remains the primary cause of mortality in cancer patients. Yet the number of available in vitro models to study metastasis is limited by challenges in the recapitulation of the metastatic microenvironment in vitro, and by difficult
Autor:
Mohamed M. Altabbaa, Eva J. Brotslaw, Michael E. Werner, Sun K. Kim, Jennifer W. Mitchell, Siwei Zhang, Brian J. Mitchell
Publikováno v:
The Journal of Cell Biology
Kim et al. show that CLAMP regulates planar cell polarity (PCP) signaling. Its depletion causes a loss of the atypical cadherin Celsr2, a loss of PCP protein asymmetry, and a defect in cilia polarity and oriented cell division. CLAMP also, via its ro
Autor:
Ian MacLeod, Michael E. Werner, John R. Yates, Amy Shaub Maddox, Kathryn Rehain-Bell, Andrew Love
Publikováno v:
Current Biology. 27:860-867
Germ cells in most animals are connected by intercellular bridges, actin-based rings that form stable cytoplasmic connections between cells promoting communication and coordination [1]. Moreover, these connections are required for fertility [1, 2]. I
Publikováno v:
Cytoskeleton (Hoboken, N.J.). 75(10)
2-Amino-4-(3,4-[methylenedioxy]benzylamino)-6-(3-methoxyphenyl)pyrimidine (AMBMP) is a small molecule that has been previously reported to be both a Wnt agonist and a microtubule (MT) regulator. Here we report a detailed analysis of AMBMPs effects on