Zobrazeno 1 - 10
of 151
pro vyhledávání: '"Michael E Rosenfeld"'
Autor:
Rajat Gupta, Candace Chang, Fen Yin, Dawoud S Sulaiman Abdulmalek, Margarete Mehrabian, Jonathan Jacobs, Aldons J Lusis, Michael E Rosenfeld, Jesus A Araujo
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 42
Ambient air pollution exposure leads to increased cardiovascular morbidity and mortality. Previous studies support a causal link between particulate matter (PM) exposure and cardiometabolic effects including atherosclerosis. We have previously report
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 4 (2014)
Externí odkaz:
https://doaj.org/article/42ebc7166aba4e9dbfc3ce59e12dbbcb
Publikováno v:
Cardiovascular Toxicology
Uterine stress is associated with an increased risk of later life metabolic diseases. In this study, we investigated the effect of diesel exhaust (DE) exposure in utero on adult susceptibility to atherosclerosis in genetically hyperlipidemic mice. Pr
Abstract 17401: Diesel Exhaust Induces Mitochondrial Dysfunction, Hyperlipidemia and Liver Steatosis
Autor:
Fen Yin, Will Driscoll, Dawoud Sulaiman, Laurent Vergnes, Jerry Ricks, Gajalakshmi Ramanathan, James Stewart, Margarete Mehrabian, Simon W Beaven, Karen Reue, Aldons J Lusis, Michael E Rosenfeld, Jesus A Araujo
Publikováno v:
Circulation, vol 138, iss Suppl_1
Introduction: Air pollution associates with increased cardiovascular morbidity and mortality, partly due to induction of dyslipidemia and metabolic syndrome. Our goal was to dissect mechanisms involved. Hypothesis: Diesel exhaust exposure induces hyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::476d21f51718cec83964dfbbc1ceab4c
https://escholarship.org/uc/item/2sz613fj
https://escholarship.org/uc/item/2sz613fj
Autor:
Rajat Gupta, Gajalakshmi Ramanathan, Yuki Zhao, Fen Yin, Jerry Ricks, Michael E Rosenfeld, Xia Yang, Jesus A Araujo
Publikováno v:
Circulation. 138
Introduction: Previous animal studies have shown that long exposures to particulate matter (PM) and diesel exhaust particles (DEP) promote atherosclerosis. Air pollutants are also reported to cause nonalcoholic steatohepatitis (NASH), liver fibrosis
Autor:
Michael E. Rosenfeld, Elaine W. Raines, E. Richard Stanley, Jeremy M. Frey, Jingjing Tang, Clemence Levet, Angela Moncada-Pazos, Matthew Freeman, Carole L. Wilson, Karin E. Bornfeldt
Publikováno v:
Molecular and Cellular Biology. 38(17)
Macrophages are prominent cells in acute and chronic inflammatory diseases. Recent studies highlight a role for macrophage proliferation post-monocyte recruitment under inflammatory conditions. Using an acute peritonitis model, we identify a signific
Autor:
Matthew Freeman, Michael E. Rosenfeld, Jeremy M. Frey, Clemence Levet, Elaine W. Raines, E. R Stanley, Carole L Wilson, Karin E. Bornfeldt, Jingjing Tang, Angela Moncada-Pazos
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 38
Recent studies highlight a role for macrophage proliferation post monocyte recruitment in inflammatory conditions, such as atherosclerosis. However, the mechanisms regulating macrophage proliferation are not well understood. Using an acute peritoniti
Publikováno v:
Atherosclerosis. 270
BACKGROUND AND AIMS: Recent in vitro studies have showed that in macrophages deletion of the non-selective Ca(2+)-permeable channel TRPC3 impairs expression of the osteogenic protein BMP-2. The pathophysiological relevance of this effect in atheroscl
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 37
Objective: Chronic kidney disease (CKD) greatly increases the risk of cardiovascular disease morbidity and mortality. Mounting data has identified the receptor activator of NF-κB (RANK) pathway as an important mediator of the accelerated atheroscler
Autor:
Bunyen Teng, Peggy Robinet, Michael E. Rosenfeld, Mary E. Davis, Jonathan D. Smith, R. Ray Morrison, S. Jamal Mustafa
Publikováno v:
Cardiovascular Research. 102:157-165
Aims The goal of this study was to determine whether the A1 adenosine receptor (AR) plays a role in atherosclerosis development and to explore its potential mechanisms. Methods and results Double knockout (DKO) mice, deficient in the genes encoding A