Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Michael E Pique"'
Autor:
Darly J Manayani, Diane Thomas, Kelly A Dryden, Vijay Reddy, Marc E Siladi, John M Marlett, G Jonah A Rainey, Michael E Pique, Heather M Scobie, Mark Yeager, John A T Young, Marianne Manchester, Anette Schneemann
Publikováno v:
PLoS Pathogens, Vol 3, Iss 10, Pp 1422-1431 (2007)
The recent use of Bacillus anthracis as a bioweapon has stimulated the search for novel antitoxins and vaccines that act rapidly and with minimal adverse effects. B. anthracis produces an AB-type toxin composed of the receptor-binding moiety protecti
Externí odkaz:
https://doaj.org/article/efaaff123dac40f995946f73e1a8860d
Publikováno v:
Biochemistry. 56:6329-6342
Protein-protein interactions are essential for biological function, but structures of protein-protein complexes are difficult to obtain experimentally. To derive the protein complex of the DNA-repair enzyme human uracil-DNA-glycosylase (hUNG) with it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36ba81af77d0f4807b6401f953cc72f5
https://doi.org/10.1021/acs.biochem.7b00643
https://doi.org/10.1021/acs.biochem.7b00643
Autor:
Qiyin Lin, Barbara Sartori, Alon A. Gorodetsky, Victoria A. Roberts, Long Phan, Sigrid Bernstorff, Chenhui Zhu, Rylan Kautz, Yegor Van Dyke, Michael E. Pique, Benedetta Marmiroli, Sheng Li, Andy Arvai, Elizabeth D. Getzoff, Kyle L. Naughton, Justin P. Kerr, Erica M. Leung, Mahan Naeim, Mercedeez J. Aquino
Publikováno v:
Advanced Materials. 28:8405-8412
Films from the cephalopod protein reflectin demonstrate multifaceted functionality as infrared camouflage coatings, proton transport media, and substrates for growth of neural stem cells. A detailed study of the in vitro formation, structural charact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dde400fa447a993861e9d1ac582eb95
https://doi.org/10.1002/adma.201601666
https://doi.org/10.1002/adma.201601666
Autor:
Stefano Forli, Michael E. Pique, Michel F. Sanner, Ruth Huey, David S. Goodsell, Arthur J. Olson
Publikováno v:
Nature Protocols. 11:905-919
Computational docking can be used to predict bound conformations and free energies of binding for small molecule ligands to macromolecular targets. Docking is widely used for the study of biomolecular interactions and mechanisms, and is applied to st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63030ac0624bf03e03883e17e316bcfa
https://doi.org/10.1038/nprot.2016.051
https://doi.org/10.1038/nprot.2016.051
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 81:2106-2118
Protein-DNA interactions are essential for many biological processes, X-ray crystallography can provide high-resolution structures, but protein-DNA complexes are difficult to crystallize and typically contain only small DNA fragments. Thus, there is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19ee70cc5209b4a4393d8ba673f42490
https://doi.org/10.1002/prot.24395
https://doi.org/10.1002/prot.24395
Publikováno v:
Journal of Computational Chemistry. 34:1743-1758
Computational docking is a useful tool for predicting macromolecular complexes, which are often difficult to determine experimentally. Here, we present the DOT2 software suite, an updated version of the DOT intermolecular docking program. DOT2 provid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37fe9c035d1c4c46166006af8f784cf2
https://doi.org/10.1002/jcc.23304
https://doi.org/10.1002/jcc.23304
Autor:
Jon Huntoon, Elizabeth D. Getzoff, Michael E. Pique, Arthur J. Olson, Jodi L. Davenport, Adam Gardner
Publikováno v:
Structure (London, England : 1993). 25(4)
Structural molecular biology is now becoming part of high school science curriculum thus posing a challenge for teachers who need to convey three-dimensional (3D) structures with conventional text and pictures. In many cases even interactive computer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5057f8ac138c3d1c54dbb8dfe36c79f7
https://pubmed.ncbi.nlm.nih.gov/28380340
https://pubmed.ncbi.nlm.nih.gov/28380340
Autor:
Michael Weinfeld, John A. Tainer, Scott Classen, Michael E. Pique, Rajam S. Mani, Shujuan Fang, Michal Hammel, David C. Schriemer, Mona Liu, Susan P. Lees-Miller, Yaping Yu, Brandi L. Mahaney, Martial Rey
Publikováno v:
The Journal of Biological Chemistry
The XRCC4-like factor (XLF)-XRCC4 complex is essential for nonhomologous end joining, the major repair pathway for DNA double strand breaks in human cells. Yet, how XLF binds XRCC4 and impacts nonhomologous end joining functions has been enigmatic. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6aa38f4b8f177d87eaf5f53ed3b9453
http://europepmc.org/articles/PMC3173232
http://europepmc.org/articles/PMC3173232
Autor:
Michael E. Pique, Melissa Brock, Sheng Li, Mindy S. Lim, Juliana Li, Lisa Craig, Virgil L. Woods
Publikováno v:
Structure. 16(1):137-148
The bacterial pathogen Vibrio cholerae uses toxin-coregulated pili (TCP) to colonize the human intestine, causing the severe diarrheal disease cholera. TCP are long, thin, flexible homopolymers of the TcpA subunit that self-associate to hold cells to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5f91d692adbb83fad9e0bbc93408d88
Autor:
Omer Katzenelson, Dennis Law, Victoria A. Roberts, Lynn F. Ten Eyck, Julie C. Mitchell, Igor F. Tsigelny, Michael E. Pique
Publikováno v:
Proteins: Structure, Function, and Genetics. 52:33-40
We present an evaluation of our results for the first Critical Assessment of PRedicted Interaction (CAPRI). The methods used include the molecular docking program DOT, shape analysis tool FADE, cluster analysis and filtering based on biological data.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4addd69df24834503da05e439b15bb7e
https://doi.org/10.1002/prot.10395
https://doi.org/10.1002/prot.10395