Zobrazeno 1 - 10
of 179
pro vyhledávání: '"Michael E P, Murphy"'
Dissecting components of the Campylobacter jejuni fetMP-fetABCDEF gene cluster under iron limitation
Autor:
Tomas Richardson-Sanchez, Anson C. K. Chan, Brendil Sabatino, Helen Lin, Erin C. Gaynor, Michael E. P. Murphy
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 1 (2024)
ABSTRACT Campylobacter jejuni is a leading cause of bacterial gastroenteritis worldwide. Acute infection can be an antecedent to highly debilitating long-term sequelae. The expression of iron acquisition systems is vital for C. jejuni to survive the
Externí odkaz:
https://doaj.org/article/983e1be7015c46ff8f34e0d904fd628d
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 6 (2023)
ABSTRACT Burkholderia cenocepacia is an opportunistic pathogen correlated with increased disease severity and mortality in cystic fibrosis (CF) patients. One major difficulty when treating these infections in CF is the poor relationship between in vi
Externí odkaz:
https://doaj.org/article/45d9b367c5814c3c8c7382ba49a88098
Autor:
Dmytro Voskoboinyk, Niusha Mahmoodi, Chang Sheng‐Huei Lin, Michael E. P. Murphy, Martin E. Tanner
Publikováno v:
ChemBioChem.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1067d7abb04f332894f4adb30595b396
https://doi.org/10.1002/cbic.202300205
https://doi.org/10.1002/cbic.202300205
Autor:
Robert G. Mothersole, Maxim Kolesnikov, Anson C. K. Chan, Emmanuella Oduro, Michael E. P. Murphy, Kirsten R. Wolthers
Publikováno v:
Biochemistry. 61:1378-1391
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18bf79ac2f4c0da28b5c3cbb11508627
https://doi.org/10.1021/acs.biochem.2c00197
https://doi.org/10.1021/acs.biochem.2c00197
Autor:
Martha M. Liu, Christine J. Boinett, Anson C. K. Chan, Julian Parkhill, Michael E. P. Murphy, Erin C. Gaynor
Publikováno v:
mBio, Vol 9, Iss 4 (2018)
ABSTRACT Campylobacter jejuni is a pathogenic bacterium that causes gastroenteritis in humans yet is a widespread commensal in wild and domestic animals, particularly poultry. Using RNA sequencing, we assessed C. jejuni transcriptional responses to m
Externí odkaz:
https://doaj.org/article/fd91b5ce7f24434ab035a653ed868d4b
Autor:
Julienne C Kaiser, Alyssa N King, Jason C Grigg, Jessica R Sheldon, David R Edgell, Michael E P Murphy, Shaun R Brinsmade, David E Heinrichs
Publikováno v:
PLoS Genetics, Vol 14, Iss 1, p e1007159 (2018)
Staphylococcus aureus requires branched-chain amino acids (BCAAs; isoleucine, leucine, valine) for protein synthesis, branched-chain fatty acid synthesis, and environmental adaptation by responding to their availability via the global transcriptional
Externí odkaz:
https://doaj.org/article/0379a43205b24fb3b33be7c2044d0e2a
Autor:
Omar M. El-Halfawy, Javier Klett, Rebecca J. Ingram, Slade A. Loutet, Michael E. P. Murphy, Sonsoles Martín-Santamaría, Miguel A. Valvano
Publikováno v:
mBio, Vol 8, Iss 2 (2017)
ABSTRACT The potential for microbes to overcome antibiotics of different classes before they reach bacterial cells is largely unexplored. Here we show that a soluble bacterial lipocalin produced by Burkholderia cenocepacia upon exposure to sublethal
Externí odkaz:
https://doaj.org/article/26004c45d3264251a4055de0fd997b9b
Autor:
Shankar Subramaniam, David Veesler, Lauren Carter, David Novack, Claire Sydeman, Jane Fontenot, Douglas E. Ferrell, Galit Alter, Robbert van der Most, Robert L. Coffman, Elizabeth Kepl, Mary Jane Navarro, Alexander G. White, Ching-Lin Hsieh, Kenneth S. Plante, Francois Villinger, Katharina Röltgen, Prabhu S. Arunachalam, Alexandra C. Walls, Jason S. McLellan, Lisa Shirreff, Rino Rappuoli, Sally Shin, Venkata Viswanadh Edara, Jessica A. Plante, Brooke Fiala, Stephanie Fischinger, Chunfeng Li, Caroline Atyeo, Matthew J. Gorman, Chad J. Roy, Scott D. Boyd, Bali Pulendran, Kasi E. Russell-Lodrigue, Skye Spencer, Xiaoying Shen, Shakti Gupta, Derek T. O'Hagan, Pyone P. Aye, Meera Trisal, Neil P. King, JoAnne L. Flynn, Nadia A. Golden, Marcos C. Miranda, Michael E. P. Murphy, John C. Kraft, Mehul S. Suthar, Lilin Lai, Jason Dufour, Rudolph Bohm, Deleah Pettie, Lara A. Doyle-Meyers, David C. Montefiori, Christopher Monjure, Kenneth A. Rogers, Samuel Wrenn, Harry Kleanthous, Nicholas J. Maness, Jay Rappaport, Alex Lee Zhu, Natalie Brunette
Publikováno v:
Nature. 594:253-258
The development of a portfolio of COVID-19 vaccines to vaccinate the global population remains an urgent public health imperative1. Here we demonstrate the capacity of a subunit vaccine, comprising the SARS-CoV-2 spike protein receptor-binding domain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::442cf7639520da9f4126cb4a6dcc72fb
https://doi.org/10.1038/s41586-021-03530-2
https://doi.org/10.1038/s41586-021-03530-2
Autor:
Masaru Kanekiyo, Lance Stewart, George Ueda, Rashmi Ravichandran, Nick Matheson, Miklos Guttman, Young-Jun Park, David Veesler, John R. Mascola, Syed M. Moin, Adrian Creanga, Barney S. Graham, Daniel Ellis, John R. Vaile, Deleah Pettie, Geoffrey B. Hutchinson, David Baker, Sila Ataca, Lauren Carter, Michael E. P. Murphy, Oliver J. Acton, Rebecca A. Gillespie, Michelle C. Crank, Neil P. King, Seyhan Boyoglu-Barnum, Sally Kephart, Michael J. Watson, Kelly K. Lee
Publikováno v:
Nature
Influenza vaccines that confer broad and durable protection against diverse viral strains would have a major effect on global health, as they would lessen the need for annual vaccine reformulation and immunization1. Here we show that computationally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc566257472cb8f9c45fdebbd4a3da49
http://europepmc.org/articles/PMC8269962
http://europepmc.org/articles/PMC8269962
Publikováno v:
The Journal of Pediatrics. 228:297-300
We present the case of a 3-month-old infant with severe, persistent bronchoconstriction following administration of rocuronium. This observation raises awareness of a rare but potentially life-threatening reaction to neuromuscular blocking agents.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38770ce2af2118900928455eb91e2ef6
https://doi.org/10.1016/j.jpeds.2020.08.031
https://doi.org/10.1016/j.jpeds.2020.08.031