Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Michael E, Hibbing"'
Autor:
Gisela Di Venanzio, Ana L. Flores-Mireles, Juan J. Calix, M. Florencia Haurat, Nichollas E. Scott, Lauren D. Palmer, Robert F. Potter, Michael E. Hibbing, Laura Friedman, Bin Wang, Gautam Dantas, Eric P. Skaar, Scott J. Hultgren, Mario F. Feldman
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Acinetobacter baumannii is generally considered an opportunistic pathogen. Here, Di Venanzio et al. develop a mouse model of catheter-associated urinary tract infection and show that a plasmid confers niche specificity to an A. baumannii urinary isol
Externí odkaz:
https://doaj.org/article/5cb55da71c7c462c8372f4c556e3c243
Publikováno v:
mBio, Vol 11, Iss 5 (2020)
ABSTRACT Urinary tract infections (UTIs) are predominantly caused by uropathogenic Escherichia coli (UPEC). UPEC pathogenesis requires passage through a severe population bottleneck involving intracellular bacterial communities (IBCs) that are clonal
Externí odkaz:
https://doaj.org/article/23fc2786fb1345899573ba2c852d6774
Autor:
Matt S. Conover, Maria Hadjifrangiskou, Joseph J. Palermo, Michael E. Hibbing, Karen W. Dodson, Scott J. Hultgren
Publikováno v:
mBio, Vol 7, Iss 2 (2016)
ABSTRACT Uropathogenic Escherichia coli (UPEC) is the primary etiological agent of over 85% of community-acquired urinary tract infections (UTIs). Mouse models of infection have shown that UPEC can invade bladder epithelial cells in a type 1 pilus-de
Externí odkaz:
https://doaj.org/article/f6b8f3861da246f0b41276a74d832bad
Publikováno v:
mBio, Vol 6, Iss 4 (2015)
ABSTRACT Uropathogenic Escherichia coli (UPEC) is the primary cause of community-acquired urinary tract infections (UTIs). UPEC bind the bladder using type 1 pili, encoded by the fim operon in nearly all E. coli. Assembled type 1 pili terminate in th
Externí odkaz:
https://doaj.org/article/632b3e125a5848dda989ed9d3a9b2597
Autor:
Alexandra J. Weisberg, Hardy Gg, Jinwoo Kim, Jeff H. Chang, Thomas Danhorn, Jing Xu, Ramya Natarajan, Michael E. Hibbing, Peter M. Merritt, Maureen C. Onyeziri, Clay Fuqua, Ian P. Reynolds
Publikováno v:
Mol Microbiol
SummaryAgrobacterium tumefaciens, is a member of the Alphaproteobacteria that pathogenizes plants, and associates with biotic and abiotic surfaces via a single cellular pole.A. tumefaciensproduces the unipolar polysaccharide (UPP) at the site of surf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e853aca4d35e6509786a9f5d08ab390
https://doi.org/10.1101/2021.04.22.440995
https://doi.org/10.1101/2021.04.22.440995
Publikováno v:
mBio
mBio, Vol 11, Iss 5 (2020)
mBio, Vol 11, Iss 5 (2020)
Uropathogenic Escherichia coli (UPEC) is the most common cause of human urinary tract infection (UTI). Population bottlenecks during early stages of UTI make high-throughput screens impractical for understanding clinically important later stages of U
Autor:
Bin Wang, Juan J Calix, Nichollas E. Scott, Michael E. Hibbing, Gautam Dantas, Robert F. Potter, Eric P. Skaar, Lauren D. Palmer, Ana L. Flores-Mireles, M. Florencia Haurat, Laura E. Friedman, Gisela Di Venanzio, Mario F. Feldman, Scott J. Hultgren
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Multidrug resistant (MDR) Acinetobacter baumannii poses a growing threat to global health. Research on Acinetobacter pathogenesis has primarily focused on pneumonia and bloodstream infections, even though one in five A. baumannii strains are isolated
Autor:
Ryan Chugani, Michael E. Hibbing, Amarendar Reddy Maddirala, Scott J. Hultgren, Vasilios Kalas, Matt S. Conover, Laurel Mydock-McGrane, Jerome S. Pinkner, James W. Janetka
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance The emergence of multidrug-resistant bacteria, including uropathogenic Escherichia coli (UPEC), makes the development of targeted antivirulence therapeutics a critical focus of research. During urinary tract infections (UTIs), UPEC uses
Autor:
Thomas J. Hannan, Wen-Chi Chou, Ashlee M. Earl, Thomas M. Hooton, Jonathan Livny, Abigail L. Manson, Michael E. Hibbing, Karen W. Dodson, Matt S. Conover, Henry L. Schreiber, Ann E. Stapleton, Scott J. Hultgren, Pacita L. Roberts
Publikováno v:
Science Translational Medicine. 9
Urinary tract infections (UTIs) are caused by uropathogenic Escherichia coli (UPEC) strains. In contrast to many enteric E. coli pathogroups, no genetic signature has been identified for UPEC strains. We conducted a high-resolution comparative genomi
Autor:
Thomas J. Hannan, James W. Janetka, Jerome S. Pinkner, Alex S. Holehouse, Karen W. Dodson, Michael E. Hibbing, Niraj H. Tolia, Michael L. Gross, Vasilios Kalas, Rohit V. Pappu, Scott J. Hultgren, Hao Zhang
Publikováno v:
Science Advances
Evolutionary selection fine-tunes conformational ensembles of FimH for optimal bladder colonization by E. coli during UTI.
Positive selection in the two-domain type 1 pilus adhesin FimH enhances Escherichia coli fitness in urinary tract infectio
Positive selection in the two-domain type 1 pilus adhesin FimH enhances Escherichia coli fitness in urinary tract infectio