Zobrazeno 1 - 10
of 341
pro vyhledávání: '"Michael E, Goldberg"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Consensus is rapidly building to support a role for the cerebellum beyond motor function, but its contributions to non-motor learning remain poorly understood. Here, we provide behavioral, anatomical and computational evidence to demonstrate
Externí odkaz:
https://doaj.org/article/8dfc1cc342d446e38f6a359132abbcdb
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113820- (2024)
Summary: The nature and function of perisaccadic receptive field (RF) remapping have been controversial. We use a delayed saccade task to reduce previous confounds and examine the remapping time course in the lateral intraparietal area and frontal ey
Externí odkaz:
https://doaj.org/article/12cf27be7a134693b8887f71ac4ffbca
Publikováno v:
Frontiers in Computational Neuroscience, Vol 16 (2023)
Sensory processing is often studied by examining how a given neuron responds to a parameterized set of stimuli (tuning curve) or how a given stimulus evokes responses from a parameterized set of neurons (population response). Although tuning curves a
Externí odkaz:
https://doaj.org/article/dce8fefa7eb747cba9ca75f45a95075f
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
The role of complex spikes in reinforcement learning is still unclear. Here, the authors show that complex spikes carry multiple context based, cell type specific and learning dependent signals that are independent of changes in any motor kinematics
Externí odkaz:
https://doaj.org/article/5f7cb4276d154a56b06c6f53b9664666
Autor:
Jianhua Zhang, Hao Xu, Alexandre Reuben, Brian Alexander, Jack Lee, Tina Cascone, Jianjun Zhang, Kyle G Mitchell, Marcelo V Negrao, Stephen G Swisher, John V Heymach, Don L Gibbons, Jack A Roth, Ferdinandos Skoulidis, Yasir Y Elamin, Xiuning Le, Anne Tsao, Chang-Jiun Wu, Vincent A Miller, Bonnie S Glisson, Karthikeyan Murugesan, Meagan Montesion, Garrett Frampton, Katja Schulze, Ilze Bara, Vincent Shen, Sylvia Hu, Dawen Sui, Michael E Goldberg, David S Barreto, Jacqulyne P Robichaux, Carl M Gay, Lingzhi Hong, Waree Rinsurongkawong, Vassiliki Papadimitrakopoulou, Gaurav Singal, Lee A Albacker, David Shames
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 8 (2021)
Background Non-small cell lung cancer (NSCLC) patients bearing targetable oncogene alterations typically derive limited benefit from immune checkpoint blockade (ICB), which has been attributed to low tumor mutation burden (TMB) and/or PD-L1 levels. W
Externí odkaz:
https://doaj.org/article/deb634044c5641f5a4d7746a8b39b598
Autor:
Jacob Rinaldi, Ethan S Sokol, Ryan J Hartmaier, Sally E Trabucco, Garrett M Frampton, Michael E Goldberg, Lee A Albacker, Anneleen Daemen, Gerard Manning
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0231999 (2020)
BACKGROUND:Metastatic breast cancer is the leading cause of cancer death in women, but the genomics of metastasis in breast cancer are poorly studied. METHODS:We explored a set of 11,616 breast tumors, including 5,034 metastases, which had undergone
Externí odkaz:
https://doaj.org/article/e81498c1e35142d48e4ab77d0cad9f43
Autor:
Timothy R. Wilson, Mark R. Lackner, Lori S. Friedman, Ciara Metcalfe, Michael E. Goldberg, Ethan S. Sokol, Wei Zhou, Carol O'Brien, Heidi M. Savage, Heather M. Moore
Supplementary Figure S7: MCF-7 DOX-inducible ER-alpha overexpressing cells without DOX induction respond similarly to taselisib and/or fulvestrant as MCF-7 parental cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1323ac6db0d9fe0223a192df2d5d72c5
https://doi.org/10.1158/1535-7163.22505926.v1
https://doi.org/10.1158/1535-7163.22505926.v1
Autor:
Henry Friedman, Nancy Haigwood, Nancy Ator, William Newsome, James S. Allan, Thaddeus G. Golos, Jeffrey H. Kordower, Robert E. Shade, Michael E. Goldberg, Matthew R. Bailey, Paul Bianchi
Publikováno v:
Pathogens and Immunity, Vol 2, Iss 3, Pp 352-365 (2017)
Research with nonhuman primates (NHPs) – monkeys for the most part – has led to critical health advances that have saved or improved millions of human lives. While NHPs account for just one-half of one percent of animals in current medical resear
Externí odkaz:
https://doaj.org/article/a8f78a2c4e1a4cc6ac1bcc1c9e3a3ffb
Autor:
Doron Lipson, Philip J. Stephens, Vincent Miller, Jeffrey S. Ross, Garrett M. Frampton, Samuel Chiacchia, Julia A. Elvin, James Suh, Shakti Ramkissoon, Michael E. Goldberg, Jie He, Mark Bailey, Juliann Chmielecki, Lee A. Albacker, Ryan J. Hartmaier
This file contains supplemental tables S1-S7. The data contained are as follows: (Table S1) Gene lists on the FoundationOne assay, (Table S2) Sample counts per disease, (Table S3) Foundation Medicine sample counts compared to TCGA sample counts, (Tab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::216d80f5d78ac81baca22c012d013899
https://doi.org/10.1158/0008-5472.22418097
https://doi.org/10.1158/0008-5472.22418097
Autor:
Barry S. Taylor, Ingo K. Mellinghoff, Lisa M. DeAngelis, Marc Rosenblum, Cameron W. Brennan, Viviane S. Tabar, Timothy A. Chan, Philip H. Gutin, Alexandra M. Miller, Anna F. Piotrowski, Mariza Daras, Adrienne Boire, Christian Grommes, Jacqueline B. Stone, Eli L. Diamond, Thomas J. Kaley, Igor T. Gavrilovic, Antonio Omuro, Elena Pentsova, Craig P. Nolan, T. Jonathan Yang, Kathryn Beal, Allison Hyde, Malbora Manne, Andrew T. McKeown, Shweta S. Chavan, Shahiba Q. Ogilvie, Maryam Pourmaleki, Juliann Chmielecki, Michael E. Goldberg, Diana Mandelker, Zsofia K. Stadler, Angela G. Arnold, David B. Solit, Marc Ladanyi, Ahmet Zehir, Michael F. Berger, Bob T. Li, David M. Hyman, Natalie M. DiStefano, Robert J. Young, Andrew L. Lin, Philip Jonsson
Figure S1: Distribution of systemic therapies received. Figure S2: Number of sequenced samples per patient. Figure S3: Subgroup-defining genomic lesions in IDH-wildtype and -mutant gliomas. Figure S4: Frequency of mutations in primary tumors. Figure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c4027dff8635107fa41557a7b76e27f
https://doi.org/10.1158/1078-0432.22472186
https://doi.org/10.1158/1078-0432.22472186