Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Michael E, Danielson"'
Autor:
Anissa S. H. Chan, Takashi O. Kangas, Xiaohong Qiu, Mark T. Uhlik, Ross B. Fulton, Nadine R. Ottoson, Keith B. Gorden, Yumi Yokoyama, Michael E. Danielson, Trinda M. Jevne, Kyle S. Michel, Jeremy R. Graff, Nandita Bose
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Imprime PGG (Imprime) is in late-stage clinical development as a combinatorial agent with several therapeutic modalities. Here we present pre-clinical mechanistic data supportive of Imprime, a soluble yeast β-1,3/1,6-glucan pathogen-associated molec
Externí odkaz:
https://doaj.org/article/3ecab3a75dcc4fa29265f88741647ad9
Autor:
Anissa S H Chan, Adria Bykowski Jonas, Xiaohong Qiu, Nadine R Ottoson, Richard M Walsh, Keith B Gorden, Ben Harrison, Peter J Maimonis, Steven M Leonardo, Kathleen E Ertelt, Michael E Danielson, Kyle S Michel, Mariana Nelson, Jeremy R Graff, Myra L Patchen, Nandita Bose
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0165909 (2016)
Imprime PGG (Imprime), an intravenously-administered, soluble β-glucan, has shown compelling efficacy in multiple phase 2 clinical trials with tumor targeting or anti-angiogenic antibodies. Mechanistically, Imprime acts as pathogen-associated molecu
Externí odkaz:
https://doaj.org/article/357100ff914f42d797e55b32fe9e7a5d
Autor:
Will Paul M, Ryan R. Langeslay, Michael E. Danielson, Lindsay R. Wurst, Vanessa A. Iiams, Andrew S. Magee
Publikováno v:
Biopolymers. 103:665-674
Scleroglucan is a β-(1,3)-glucan which is highly branched at the 6-position with a single glucose residue. Acid hydrolysis of a high molecular weight scleroglucan gave a medium molecular weight, freely soluble material. Linkage analysis by the parti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9acb0130cfadc2ec9d87caa03fef89f
https://doi.org/10.1002/bip.22685
https://doi.org/10.1002/bip.22685
Autor:
Ben J. Harrison, Nandita Bose, Xiaohong Qiu, Kyle S. Michel, Jeremy R. Graff, Richard Walsh, Mariana I. Nelson, Nadine R. Ottoson, Adria Jonas, Keith B. Gorden, Steven M. Leonardo, Michael E. Danielson, Kathleen E. Ertelt, Peter Maimonis, Anissa S.H. Chan, Myra L. Patchen
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 11, p e0165909 (2016)
PLoS ONE, Vol 11, Iss 11, p e0165909 (2016)
Imprime PGG (Imprime), an intravenously-administered, soluble β-glucan, has shown compelling efficacy in multiple phase 2 clinical trials with tumor targeting or anti-angiogenic antibodies. Mechanistically, Imprime acts as pathogen-associated molecu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f58209753cfca1dd1d9d1f444649633e
http://europepmc.org/articles/PMC5094785
http://europepmc.org/articles/PMC5094785
Autor:
Michael E. Danielson, Will Paul M, Andrew S. Magee, Rosmarie Dauth, Ryan R. Langeslay, Natalie Elmasry
Publikováno v:
Journal of Agricultural and Food Chemistry. 58:10305-10308
An enzymatic method to measure β-glucan content (GEM assay) is applicable in a variety of matrices. The method is composed of swelling the sample with KOH and initial digestion with a lyticase, which is followed by treatment with a mixture of exo-1,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba2f5d752058be811c6c5af0531d6cff
https://doi.org/10.1021/jf102003m
https://doi.org/10.1021/jf102003m
Publikováno v:
Angewandte Chemie. 120:9889-9892
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b50dce10364f8a11d2655f763ed09000
https://doi.org/10.1002/ange.200804049
https://doi.org/10.1002/ange.200804049
Autor:
Kyle J. Lindstrom, Philip D. Heppner, Daniel J Willie, Michael E. Danielson, Charles M. Leir, Joshua R. Wurst, Gregory D. Lundquist, Sonja S. Mackey, Tushar A. Kshirsagar, Chad A. Haraldson, David S. Hays, Karl E. Benson
Publikováno v:
The Journal of Organic Chemistry. 72:4570-4573
The deprotonation and regioselective reaction of 2H-pyrazolo[3,4-c]quinolines with a variety of electrophiles is described. Electrophiles include benzaldehyde, DMF, carbon dioxide, and iodine. This method provides a direct route to a class of pharmac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b0237f06064236349491db0ad2186ef
https://doi.org/10.1021/jo070392t
https://doi.org/10.1021/jo070392t
Autor:
Andrew S, Magee, Ryan R, Langeslay, Paul M, Will, Michael E, Danielson, Lindsay R, Wurst, Vanessa A, Iiams
Publikováno v:
Biopolymers. 103(12)
Scleroglucan is a β-(1,3)-glucan which is highly branched at the 6-position with a single glucose residue. Acid hydrolysis of a high molecular weight scleroglucan gave a medium molecular weight, freely soluble material. Linkage analysis by the parti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::613eb1ea7f0b4c31b61f494313a80d16
https://pubmed.ncbi.nlm.nih.gov/26015027
https://pubmed.ncbi.nlm.nih.gov/26015027
Autor:
Mark T. Uhlik, Michael E. Danielson, Nadine R. Ottoson, Nandita Bose, Jamie Lowe, Jeremy R. Graff, Richard D. Huhn, Ben Harrison, Xiaohong Qiu, Steven M. Leonardo, Jose Iglesias, Myra L. Patchen, Anissa S.H. Chan, Kyle S. Michel, M. Ma, Keith B. Gorden, Richard Walsh, Katie Ertelt, A. Bykowski Jonas
Publikováno v:
European Journal of Cancer. 69:S106-S107
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7d2aa074c715ae052c2b188168d97a0
https://doi.org/10.1016/s0959-8049(16)32915-x
https://doi.org/10.1016/s0959-8049(16)32915-x
Autor:
Michael E. Danielson, Ross B. Fulton, Kyle S. Michel, Keith B. Gorden, Jeremy R. Graff, Steven M. Leonardo
Publikováno v:
Cancer Research. 77:1703-1703
Significant clinical and pre-clinical research has shown that PAMPs- Pathogen Associated Molecular Patterns- can trigger an integrated anti-cancer immune response involving both innate and adaptive immunity. Imprime PGG is a soluble yeast β-1,3/1,6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e3d6ef6f3a2ab4e934ddf74c5c5a75f
https://doi.org/10.1158/1538-7445.am2017-1703
https://doi.org/10.1158/1538-7445.am2017-1703