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pro vyhledávání: '"Michael Donegan"'
Publikováno v:
Analytical chemistry. 94(34)
A membrane-based electrodialytic desalter has been developed for the selective removal of buffer/salt constituents from a fluid stream while retaining larger charged molecules such as proteins prior to mass spectrometric (MS) detection. The salts are
Autor:
Michael Donegan, Jennifer M. Nguyen, Jason MacLean, Brooke M. Koshel, Martin Gilar, Zhimin Li, Matthew A. Lauber
Publikováno v:
Nguyen, J M, Gilar, M, Koshel, B, Donegan, M, Maclean, J, Li, Z & Lauber, M A 2021, ' Assessing the impact of nonspecific binding on oligonucleotide bioanalysis ', Bioanalysis, vol. 13, no. 16, pp. 1233-1244 . https://doi.org/10.4155/bio-2021-0115
Aim: Accurate and reliable quantification of oligonucleotides can be difficult, which has led to an increased focus on bioanalytical methods for more robust analyses. Recent advances toward mitigating sample losses on liquid chromatography (LC) syste
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 208
Nonspecific adsorption has been a consistent challenge in the analysis of oligonucleotides. Nonspecific adsorption is a result of interactions between charged acidic analytes and adsorption sites present in metallic surfaces located in the fluidic pa
Autor:
Michael Donegan
Publikováno v:
Journal of Money Laundering Control. 22:770-781
Purpose The purpose of this paper is to critically analyse research surrounding mandate fraud and to devise a crime script identifying the crime commission process. It is hoped this will assist in standardising investigation of mandate fraud by law e
Publikováno v:
Journal of Chromatography A. 1666:462860
We performed a systematic study of thirteen alkylamines used as ion-pairing reagents for ion-pair reversed-phase liquid chromatography (IP RP LC) separations of oligonucleotides on a C18 column. We proposed a method to classify the hydrophobicity of
Autor:
Marc H. Davies, Roderick T. Bunch, Robert W. Lange, Bethany R. Baumgart, Michael Donegan, Damir Simic, Theodora W. Salcedo, Kimberley A. Lentz, Terry Van Vleet, Thomas P. Sanderson
Publikováno v:
Journal of Applied Toxicology. 35:791-798
The objective of this study was to evaluate potential protective effects of vehicles containing d-α-tocopheryl polyethylene glycol 1000 succinate (TPGS), which may impact nonclinical safety assessments of oxidative processes. This was achieved by ev
Autor:
Marc Browning, Michael Donegan
Publikováno v:
Journal of Liquid Chromatography & Related Technologies. 35:2345-2363
The challenges of how to best ionize the enormous diversity of organic compounds that are of interest to the scientific community have led to advances in mass spectrometry interface design. Developments for both surface and flow ionization techniques
Publikováno v:
Analytical Chemistry. 78:1296-1305
In the field of metabonomics, 1H NMR and full scan mass spectrometry methods have usually been combined with principal component analysis (PCA) and partial least squares discriminant analysis (PLS-DA) to detect patterns in biofluids that correspond t
Infrared light is the most common choice for illumination of the eye in current eye trackers, usually produced via IR light-emitting diodes (LEDs). This chapter provides an overview of the potential hazards of over-exposure to infrared light, the saf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd12ad040a3de5a0c50b160f8dcb26bd
https://doi.org/10.4018/978-1-4666-4422-9.ch055
https://doi.org/10.4018/978-1-4666-4422-9.ch055
Autor:
Joseph Raybon, Cathy A. Andorfer, Chris Janus, Ling Yang, Mike Hutton, Jada Lewis, Lynn B. DeCarr, Nina Hoque, Donna M. Barten, Charles F. Albright, Craig Polson, Jere E. Meredith, Tracey Fiedler, Michael Donegan, Margi E. Goldstein, John P. Corradi
Publikováno v:
Alzheimer's & Dementia. 5