Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Michael Dirkmann"'
Publikováno v:
ChemBioChem. 19:2146-2151
The enzymatic synthesis of terpenes was investigated by using a cascade based on the mevalonic acid pathway. Suitable enzymes from all kingdoms of life were identified and combined to give rise to geosmin and patchoulol as representative compounds. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d4bbf4006046b6c11271af27d8a0945
https://doi.org/10.1002/cbic.201800128
https://doi.org/10.1002/cbic.201800128
Autor:
David Möller, Elsa Sanchez-Garcia, Trung Quan Luong, Frank Schulz, Roland Winter, Simon Ebbinghaus, Abir Ganguly, Walter Thiel, Michael Dirkmann, Oliver Brylski
Publikováno v:
The Journal of Physical Chemistry B. 121:6390-6398
To improve our mechanistic understanding of zinc metalloenzymes, we report a joint computational and experimental study of a minimal carbonic anhydrase (CA) mimic, a 22-residue Zn-finger hydrolase. We combine classical molecular dynamics (MD) simulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0549e4636fb4fb6d3992dba68ef5ac97
https://doi.org/10.1021/acs.jpcb.7b05027
https://doi.org/10.1021/acs.jpcb.7b05027
Autor:
Simon Ebbinghaus, Oktavian Krenczyk, Axel Rosenhahn, Andreas von Gundlach, Martin A. Schroer, Frank Schulz, Christoph Rumancev, Christian Herrmann, Javier Iglesias-Fernández, Michael Dirkmann, Pandian Sokkar, Tobias Vöpel, Elsa Sanchez-Garcia, Victor Muñoz, Julia Nowack
3-Hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase was investigated in different organic cosolvents by means of kinetic and calorimetric measurements, molecular dynamics simulations, and small-angle X-ray scattering. The combined experimental
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99c8e0657527afb7542241e72b3e1c4f
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85040742420
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85040742420
Publikováno v:
Chirality. 29(8)
The absolute configuration (AC) of the common precursor of the fusicoccane family of terpenoids, fusicocca-2,10(14)-diene (FCdiene), had only been deduced by a lengthy total synthesis, or indirectly from crystal structures of fusicoccin A. However, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bc90b8cdca9de0e3a4d2ae27c77a4b9
https://pubmed.ncbi.nlm.nih.gov/28560831
https://pubmed.ncbi.nlm.nih.gov/28560831