Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Michael Dills"'
Publikováno v:
Viruses, Vol 9, Iss 6, p 141 (2017)
In this review, we assess our current understanding of the role of bacteriophages infecting the human gut bacterial community in health and disease. In general, bacteriophages contribute to the structure of their microbial communities by driving host
Externí odkaz:
https://doaj.org/article/8a6c605a9f674b209583e44c2a748da5
Autor:
Pınar Özden, Eser, Raymond M, Paranal, Jieun, Son, Elena, Ivanova, Yanan, Kuang, Heidi M, Haikala, Ciric, To, Jeffrey J, Okoro, Kshiti H, Dholakia, Jihyun, Choi, Yoonji, Eum, Atsuko, Ogino, Pavlos, Missios, Dalia, Ercan, Man, Xu, Michael J, Poitras, Stephen, Wang, Kenneth, Ngo, Michael, Dills, Masahiko, Yanagita, Timothy, Lopez, Mika, Lin, Jeanelle, Tsai, Nicolas, Floch, Emily S, Chambers, Jennifer, Heng, Rana, Anjum, Alison D, Santucci, Kesi, Michael, Alwin G, Schuller, Darren, Cross, Paul D, Smith, Geoffrey R, Oxnard, David A, Barbie, Lynette M, Sholl, Magda, Bahcall, Sangeetha, Palakurthi, Prafulla C, Gokhale, Cloud P, Paweletz, George Q, Daley, Pasi A, Jänne
Publikováno v:
Science translational medicine
The clinical efficacy of epidermal growth factor receptor (EGFR)–targeted therapy in EGFR-mutant non–small cell lung cancer is limited by the development of drug resistance. One mechanism of EGFR inhibitor resistance occurs through amplification
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::22efb640067814269983395f20ecc3cd
https://pubmed.ncbi.nlm.nih.gov/34516823
https://pubmed.ncbi.nlm.nih.gov/34516823
Autor:
Emily S. Chambers, Alwin Schuller, Stephen Wang, Dalia Ercan, Mika Lin, Pınar Özden Eser, Raymond M. Paranal, Nicolas Floc'h, Sangeetha Palakurthi, Alison D. Santucci, Jeffrey J. Okoro, Geoffrey R. Oxnard, Man Xu, Kenneth H. Ngo, Jeanelle Tsai, Ciric To, Lynette M. Sholl, George Q. Daley, Michael Dills, Pavlos Missios, Kesi Michael, Paul D. Smith, Yoonji Eum, Magda Bahcall, Yanan Kuang, David A. Barbie, Masahiko Yanagita, Jennifer C. Heng, Rana Anjum, Prafulla C. Gokhale, Elena Ivanova, Jieun Son, Kshiti Dholakia, Heidi M. Haikala, Darren Cross, Jihyun Choi, Michael J. Poitras, Pasi A. Jänne, Timothy Lopez, Cloud P. Paweletz, Atsuko Ogino
Publikováno v:
Science Translational Medicine. 13
A subset of drug-resistant EGFR -mutant MET -amplified lung cancer switches oncogenic dependence to MET and is treatable with MET inhibitor monotherapy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f7c7b3de9b86168add52ec03c24e84e
https://doi.org/10.1126/scitranslmed.abb3738
https://doi.org/10.1126/scitranslmed.abb3738
Autor:
Dimitri A. Bikos, Andrew Hoegh, Raina K. Plowright, Kristen A. Brileya, Thomas B. LeFevre, Matthew W. Fields, Isaak J Thornton, Connie B. Chang, Alexandra K. Adams, Emma Kate Loveday, James N. Wilking, Jayne Morrow, Maria Rodriguez, Michael Dills, Albert E. Parker, Matthew P. Taylor, Jason R. Carter, Chiachi Hwang, Deborah E. Keil, Seth T. Walk
Rapid testing methods can identify outbreaks and trigger preventive strategies for slowing the spread of SARS-CoV-2, the virus that causes COVID-19. The “gold-standard” detection method for SARS-CoV-2 is reverse transcription quantitative polymer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d214c34d87da01dc6c0e5ce6b8b2d1bd
https://doi.org/10.1101/2021.03.31.21254634
https://doi.org/10.1101/2021.03.31.21254634
The human body hosts a great diversity of microbes, including viruses of bacteria termed bacteriophages. Bacteriophages have been traditionally viewed in the context of pathogenesis and molecular biology. Recently, a shift has occurred toward a more
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1885d278129eebde65add5b8fb5a0b34
https://doi.org/10.1016/b978-0-12-809633-8.21226-0
https://doi.org/10.1016/b978-0-12-809633-8.21226-0
Autor:
Utsav Saxena, Wei Zhou, Boyoung Kim, Martin Koser, Eduardo Salido, Marc Abrams, Nazef Naim, Jessica Gierut, Natalie Pursell, Michael Dills, Rachel Storr, Chengjung Lai, Rohan Diwanji, Henryk T. Dudek, Cristina Martin-Higueras, Weimin Wang, Bob D. Brown, Chaitali Dutta
Publikováno v:
Molecular Therapy
Primary hyperoxalurias (PHs) are autosomal recessive disorders caused by the overproduction of oxalate leading to calcium oxalate precipitation in the kidney and eventually to end-stage renal disease. One promising strategy to treat PHs is to reduce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6180a1568b71aea97169ba805be572fb
https://doi.org/10.1016/j.ymthe.2018.05.016
https://doi.org/10.1016/j.ymthe.2018.05.016
Autor:
Michael Dills, Natalie Pursell, Rohan Diwanji, Gilles Mithieux, Marc Abrams, Rachel Storr, Henryk T. Dudek, Bob D. Brown, Jessica Gierut, Fabienne Rajas, Chengjung Lai, Weimin Wang, Margaux Raffin, Boyoung Kim, Nandini Venkat, Utsav Saxena, Jr-Shiuan Yang, Anee Shah, Wei Zhou, Monika Gjorgjieva
Publikováno v:
Molecular Therapy
Molecular Therapy, Cell Press, 2018, 26 (7), pp.1771-1782. ⟨10.1016/j.ymthe.2018.04.023⟩
Molecular Therapy, Cell Press, 2018, 26 (7), pp.1771-1782. ⟨10.1016/j.ymthe.2018.04.023⟩
Glycogen storage diseases (GSDs) of the liver are devastating disorders presenting with fasting hypoglycemia as well as hepatic glycogen and lipid accumulation, which could lead to long-term liver damage. Diet control is frequently utilized to manage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed4380aca5f029995c271c85a0b43c01
https://doi.org/10.1016/j.ymthe.2018.04.023
https://doi.org/10.1016/j.ymthe.2018.04.023
Autor:
Keshia M. Kerchner, Nikki Dellas, C. Martin Lawrence, Sheena J. Nicolay, Michael Dills, Jamie C. Snyder, Susan K. Brumfield, Mark J. Young
Publikováno v:
Journal of Virology. 90:2729-2739
Sulfolobus turreted icosahedral virus (STIV), an archaeal virus that infects the hyperthermoacidophile Sulfolobus solfataricus , is one of the most well-studied viruses of the domain Archaea . STIV shares structural, morphological, and sequence simil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15d78374ad96989d853f3d6ecdda515a
https://doi.org/10.1128/jvi.02435-15
https://doi.org/10.1128/jvi.02435-15
Publikováno v:
Viruses, Vol 9, Iss 6, p 141 (2017)
Viruses
Viruses
In this review, we assess our current understanding of the role of bacteriophages infecting the human gut bacterial community in health and disease. In general, bacteriophages contribute to the structure of their microbial communities by driving host
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afae5942b8a89969e1f38c91375e684b
http://www.mdpi.com/1999-4915/9/6/141
http://www.mdpi.com/1999-4915/9/6/141
Autor:
Michael Dills, Amanda J. Redig, Man Xu, Jessie M. English, Darren Cross, Paul Kirscmeier, Atsuko Ogino, Yanan Kuang, Cloud P. Paweletz, Jinyun Choi, Pasi A. Jänne, Sangeetha Palakurthi, Prafulla C. Gokhale, Nora Feeney
Publikováno v:
Cancer Research. 76:5192-5192
Background: Osimertinib (AZD9291)is a mutant-selective EGFR tyrosine kinase inhibitor (TKI) effective against EGFR activating and the T790M acquired resistance mutations.Osimertinib has been approved by the US FDA for patients with EGFR T790M positiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb9bee7dedde05c66a92bf7ece310a27
https://doi.org/10.1158/1538-7445.am2016-5192
https://doi.org/10.1158/1538-7445.am2016-5192