Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Michael Devos"'
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Indoleamine 2,3-dioxygenase 1 (IDO1) is a cytosolic haem-containing enzyme involved in the degradation of tryptophan to kynurenine. Although initially thought to be solely implicated in the modulation of innate immune responses during infection, subs
Externí odkaz:
https://doaj.org/article/9b04115e5b8e496e8688ddc3cba4ab79
Autor:
Ilse M Beck, Zuzanna J Drebert, Ruben Hoya-Arias, Ali A Bahar, Michael Devos, Dorien Clarisse, Sofie Desmet, Nadia Bougarne, Bart Ruttens, Valerie Gossye, Geertrui Denecker, Sam Lievens, Marc Bracke, Jan Tavernier, Wim Declercq, Kris Gevaert, Wim Vanden Berghe, Guy Haegeman, Karolien De Bosscher
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69115 (2013)
Compound A possesses glucocorticoid receptor (GR)-dependent anti-inflammatory properties. Just like classical GR ligands, Compound A can repress NF-κB-mediated gene expression. However, the monomeric Compound A-activated GR is unable to trigger gluc
Externí odkaz:
https://doaj.org/article/e7db32ca698446dba6bb65b1baa9d22c
Autor:
Denis A. Mogilenko, Delphine Staumont-Sallé, Geert van Loo, Wim Declercq, Peter Vandenabeele, Michael Devos, David Dombrowicz, Peter Tougaard, C. Becquart, Claus Bachert, Sandrine Quemener, Bart Staels, Barbara Gilbert, Hélène Dehondt, Sébastien Fleury
Publikováno v:
Journal of Investigative Dermatology. 139:135-145
Keratinocytes are key players in chronic inflammatory skin diseases. A20 regulates NF-κB-dependent expression of proinflammatory genes and cell death, but the impact of its expression in keratinocytes on systemic inflammation and skin disorders has
Autor:
Manolis Pasparakis, Peter Vandenabeele, Dario Priem, Wim Declercq, Adrian T. Ting, Geert van Loo, Michael Devos, Sarah Druw, Mathieu J.M. Bertrand, Karolina Slowicka, Arne Martens
Publikováno v:
Cell Death & Disease. 11
The original version of this article contained an error in the name of one of the co-authors (Wim Declercq). This has been corrected in the PDF and HTML versions.
Autor:
Giel Tanghe, Barbara Gilbert, Maud Verheirstraeten, Josephine Nemegeer, Sylvie Lefebvre, Peter Vandenabeele, Wim Declercq, Jolien De Munck, Jan Rehwinkel, Richard de Reuver, Michael Devos, Evelien Dierick, Jonathan Maelfait
Publikováno v:
Journal of Experimental Medicine
The Journal of Experimental Medicine
JOURNAL OF EXPERIMENTAL MEDICINE
The Journal of Experimental Medicine
JOURNAL OF EXPERIMENTAL MEDICINE
Devos et al. find that the recognition of endogenous nucleic acids by the nucleic acid sensor ZBP1 causes necroptosis of RIPK1-deficient keratinocytes. This process drives the development of an inflammatory skin disease characterized by an IL-17 immu
Autor:
Hamida Hammad, Viacheslav Mylka, Marnik Vuylsteke, Michael Devos, Bart N. Lambrecht, Lode De Cauwer, Sofie Desmet, Giel Tanghe, Jan Tavernier, Justine Van Moorleghem, Nadia Bougarne, Manon Vanheerswynghels, Karolien De Bosscher, Jonathan Thommis, Astrid Luypaert, Julie Deckers
Publikováno v:
JOURNAL OF INVESTIGATIVE DERMATOLOGY
Journal of Investigative Dermatology
Journal of Investigative Dermatology
Children with atopic dermatitis show an increased risk to develop asthma later in life, a phenomenon referred to as "atopic march," which emphasizes the need for secondary prevention therapies. This study aimed to investigate whether relief of skin i
Autor:
Peter Vandenabeele, Manolis Pasparakis, Wim Declercq, Geert van Loo, Mathieu J.M. Bertrand, Adrian T. Ting, Dario Priem, Sarah Druwé, Michael Devos, Arne Martens, Karolina Slowicka
Publikováno v:
Cell Death & Disease
CELL DEATH & DISEASE
Cell Death and Disease, Vol 10, Iss 10, Pp 1-16 (2019)
CELL DEATH & DISEASE
Cell Death and Disease, Vol 10, Iss 10, Pp 1-16 (2019)
The cytokine TNF promotes inflammation either directly by activating the MAPK and NF-κB signaling pathways, or indirectly by triggering cell death. A20 is a potent anti-inflammatory molecule, and mutations in the gene encoding A20 are associated wit
Autor:
Agnieszka Paziewska, Agata Lichawska-Cieslar, Patrycja Kwiecińska, Weronika Szukala, Roza Pietrzycka, Joanna Cichy, Michael Devos, Wim Declercq, Luis F. Santamaria-Babí, Jolanta Jura, Izabela Rumienczyk, Mingui Fu, Maria Kulecka, Piotr Konieczny, Michal Mikula, Julia Borowczyk
Publikováno v:
J Mol Med (Berl)
Journal of Molecular Medicine
Journal of Molecular Medicine
MCPIP1 (Regnase-1, encoded by the ZC3H12A gene) regulates the mRNA stability of several inflammatory cytokines. Due to the critical role of this RNA endonuclease in the suppression of inflammation, Mcpip1 deficiency in mice leads to the development o
Autor:
Rui Yi, Audrey Brisebarre, Agnieszka Checinska, Alizée Vercauteren Drubbel, Erwin Nkusi, Soufiane Boumahdi, Sandrine Lenglez, Christine Dubois, Michael Devos, Benjamin Beck, Mathilde Latil, Cédric Blanpain, Li Wang, Dany Nassar, Wim Declercq
Publikováno v:
Cell stem cell, 20 (2
Epithelial to mesenchymal transition (EMT) in cancer cells has been associated with metastasis, stemness, and resistance to therapy. Some tumors undergo EMT while others do not, which may reflect intrinsic properties of their cell of origin. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33ebd28d06492300f594cf5f17a53a26
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/241437
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/241437
Autor:
Wim Declercq, Michael Devos
Publikováno v:
Journal of Medical & Surgical Pathology.