Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Michael Devit"'
Autor:
Victoria Ledbetter, Scott Auerbach, Logan J. Everett, Beena Vallanat, Anna Lowit, Gregory Akerman, William Gwinn, Leah C. Wehmas, Michael F. Hughes, Michael Devito, J. Christopher Corton
Publikováno v:
Frontiers in Toxicology, Vol 6 (2024)
Current methods for cancer risk assessment are resource-intensive and not feasible for most of the thousands of untested chemicals. In earlier studies, we developed a new approach methodology (NAM) to identify liver tumorigens using gene expression b
Externí odkaz:
https://doaj.org/article/b05c465a5b4645b5b3f97f1d7d895f25
Autor:
David M. Crizer, Julie R. Rice, Marci G. Smeltz, Katelyn S. Lavrich, Krishna Ravindra, John F. Wambaugh, Michael DeVito, Barbara A. Wetmore
Publikováno v:
Toxics, Vol 12, Iss 9, p 672 (2024)
Toxicokinetic (TK) assays and in vitro–in vivo extrapolation (IVIVE) models are New Approach Methods (NAMs) used to translate in vitro points of departure to exposure estimates required to reach equivalent blood concentrations. Per- and polyfluoroa
Externí odkaz:
https://doaj.org/article/e1bcf9fb3f204f5fa7c8aeeeb7b6bb27
Autor:
Richard S. Judson, Doris Smith, Michael DeVito, John F. Wambaugh, Barbara A. Wetmore, Katie Paul Friedman, Grace Patlewicz, Russell S. Thomas, Risa R. Sayre, Jennifer H. Olker, Sigmund Degitz, Stephanie Padilla, Joshua A. Harrill, Timothy Shafer, Kelly E. Carstens
Publikováno v:
Toxics, Vol 12, Iss 4, p 271 (2024)
Per- and polyfluoroalkyl substances (PFAS) are widely used, and their fluorinated state contributes to unique uses and stability but also long half-lives in the environment and humans. PFAS have been shown to be toxic, leading to immunosuppression, c
Externí odkaz:
https://doaj.org/article/65a7eaa4eb3848ff8e5cf8a509a96a88
Tafamidis, a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade
Autor:
Lan Wang, Richard Labaudinière, Michael Devit, James Fleming, Stephen Connelly, Ted R. Foss, Jeffery W. Kelly, Evan T. Powers, R. Luke Wiseman, Jeff Packman, Ian A. Wilson, Charlotte Weigel, Christine Bulawa
Publikováno v:
Proceedings of the National Academy of Sciences. 109:9629-9634
The transthyretin amyloidoses (ATTR) are invariably fatal diseases characterized by progressive neuropathy and/or cardiomyopathy. ATTR are caused by aggregation of transthyretin (TTR), a natively tetrameric protein involved in the transport of thyrox
Autor:
Aero Renyer, Krishna Ravindra, Barbara A. Wetmore, Jermaine L. Ford, Michael DeVito, Michael F. Hughes, Leah C. Wehmas, Denise K. MacMillan
Publikováno v:
Toxics, Vol 11, Iss 12, p 951 (2023)
Few studies are available on the environmental and toxicological effects of perfluoroalkyl ether carboxylic acids (PFECAs), such as GenX, which are replacing legacy PFAS in manufacturing processes. To collect initial data on the toxicity and toxicoki
Externí odkaz:
https://doaj.org/article/f755faf0b693462dbddd645d9ae1fec7
Autor:
Tyler Dalton McNabb, Michael DeVito
Publikováno v:
Religions, Vol 13, Iss 10, p 926 (2022)
In this paper, informed by Vatican 2 and one of its premier modern day scholars, Gerald O’Collins, we will argue (1), that while the Christian evangelist should proclaim that Jesus is the only way to God, she should nonetheless be open to the possi
Externí odkaz:
https://doaj.org/article/535397d06dfd4315834f73fb1b0c39ff
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
Assembling all-solid-state batteries presents a unique challenge due to chemical and electrochemical complexities of interfaces between a solid electrolyte and electrodes. While the interface stability is dictated by thermodynamics, making use of pas
Externí odkaz:
https://doaj.org/article/e8c95b7428ee4071a39df79464930555
Autor:
Tyler Dalton McNabb, Michael DeVito
Publikováno v:
Religions, Vol 13, Iss 1, p 24 (2021)
Launonen and Mullins argue that if Classical Theism is true, human cognition is likely not theism-tracking, at least, given what we know from cognitive science of religion. In this essay, we develop a model for how classical theists can make sense of
Externí odkaz:
https://doaj.org/article/22840189f6af4cff99988f1524278b5a
Autor:
Michael DeVito
Publikováno v:
Religions, Vol 12, Iss 9, p 770 (2021)
This essay marks the first steps towards a viable glut-theoretic (contradictory) solution to the longstanding foreknowledge and free will dilemma. Specifically, I offer a solution to the dilemma that accommodates omniscience (foreknowledge) and human
Externí odkaz:
https://doaj.org/article/6ce031911c0f4859a005c1698fac9ecb
Autor:
Michael Devitt
Publikováno v:
Theoria, Vol 27, Iss 2, Pp 229-233 (2012)
Machery argues: (1) that “philosophers’ intuitions about reference are not more reliable than lay people’s —if anything, they are probably worse”; (2) that “intuitions about the reference of proper names and uses of proper names provide e
Externí odkaz:
https://doaj.org/article/0bdf50ef5eb949cb928912754920908c