Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Michael Deogracias"'
Autor:
Anthony Lagina, Michael Deogracias, Danielle Bazzi, Karin Reed, Lesley Foster, Rasika Chepuri, Jonathon M. Sullivan
Publikováno v:
Academic Emergency Medicine. 19:402-408
ACADEMIC EMERGENCY MEDICINE 2012; 19: 402–408 © 2012 by the Society for Academic Emergency Medicine Abstract Background: Physical and molecular mechanisms for the neuroprotective effect of therapeutic hypothermia are not completely understood, and
Publikováno v:
Neuroscience. 169:1307-1314
Transient global brain ischemia results in an immediate inhibition of protein translation upon reperfusion. During early brain reperfusion protein synthesis is inhibited by alpha subunit of eukaryotic initiation factor 2 (eIF2alpha) phosphorylation b
Autor:
Michael Deogracias, Jonathon M. Sullivan, Joseph M. Wider, Thomas H. Sanderson, Anthony Lagina, Rita Kumar, Lesley Calo
Publikováno v:
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine. 20(4)
Objectives Hypothermia has a well-established neuroprotective effect and offers a foundation for combination therapy for brain ischemia. The authors evaluated the effect of combination therapy with insulin-like growth factor-1 (IGF-1) and hypothermia
Autor:
Anthony T, Lagina, Michael, Deogracias, Karin, Reed, Danielle, Bazzi, Rasika, Chepuri, Lesley, Foster, Jonathon M, Sullivan
Publikováno v:
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine. 19(4)
Physical and molecular mechanisms for the neuroprotective effect of therapeutic hypothermia are not completely understood, and new therapeutic applications incorporating hypothermia remain to be developed and tested. Clinically relevant animal models