Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Michael Debbas"'
Autor:
Eileen White, Michael Debbas
Publikováno v:
Genes & Development. 7:546-554
Transformation of primary rodent cells by the adenovirus E1A and E1B oncogenes is a two-step process, where E1A-dependent induction of proliferation is coupled to E1B-dependent suppression of programmed cell death (apoptosis). The E1B gene encodes tw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66c6ea6ebb7f05b973bd78ae57a84eb0
https://doi.org/10.1101/gad.7.4.546
https://doi.org/10.1101/gad.7.4.546
Autor:
Eileen White, Peter Sabbatini, L. R. Gooding, William S. M. Wold, Michael Debbas, D. I. Kusher
Publikováno v:
Scopus-Elsevier
The adenovirus E1A and E1B proteins are required for transformation of primary rodent cells. When expressed in the absence of the 19,000-dalton (19K) E1B protein, however, the E1A proteins are acutely cytotoxic and induce host cell chromosomal DNA fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8345736c99140a9489e99e7016328f4f
https://doi.org/10.1128/mcb.12.6.2570-2580.1992
https://doi.org/10.1128/mcb.12.6.2570-2580.1992
Autor:
JoAnn Tuan, Annick Itie, Michael Debbas, Athena W. Lin, Sushil K. Thukral, Andrew Wakeham, Tak W. Mak, Samuel Benchimol, Ying Lu, Scott W. Lowe, Seiji Kondo, Gary Elliott, Weili Ma, Ildiko Sarosi, Chris Saris
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 100(9)
The tumor suppressor p53 is regulated in part by binding to cellular proteins. We used p53 as bait in the yeast two-hybrid system and isolated homeodomain-interacting protein kinase 1 (HIPK1) as a p53-binding protein. Deletion analysis showed that am
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1d5dbd6367506c79360f059cbe396b3
https://pubmed.ncbi.nlm.nih.gov/12702766
https://pubmed.ncbi.nlm.nih.gov/12702766
Autor:
Peter Sabbatini, Stanley Korsmeyer, Michael Debbas, David M. Hockenbery, Lakshmi Rao, Eileen White
Cooperation between the adenovirus E1A and E1B oncogenes is required for transformation of primary quiescent rodent cells. Although expression of E1A alone will stimulate cell proliferation sufficient to initiate transformed focus formation, prolifer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aadd880e7c11eb26379e567de3ad0094
https://europepmc.org/articles/PMC49787/
https://europepmc.org/articles/PMC49787/
