Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Michael De Silva"'
Autor:
Quynh Nhu Dinh, Cecilia Lo, David Wong Zhang, Vivian Tran, Tayla Gibson-Hughes, Ashleigh Sheriff, Henry Diep, Hyun Ah Kim, Shenpeng R. Zhang, Liz J. Barreto-Arce, Maria Jelinic, Antony Vinh, Thiruma V. Arumugam, Siow Teng Chan, Rebecca Lim, Grant R. Drummond, Christopher G. Sobey, T. Michael De Silva
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Vascular inflammation and fibrosis are hallmarks of hypertension and contribute to the development of cardiovascular disease and cognitive impairment. However, current anti-hypertensive drugs do not treat the underlying tissue damage, such a
Externí odkaz:
https://doaj.org/article/c612cfe46001495bb86c12c472d59be3
Autor:
Vismitha Rajeev, Yuek Ling Chai, Luting Poh, Sharmelee Selvaraji, David Y. Fann, Dong-Gyu Jo, T. Michael De Silva, Grant R. Drummond, Christopher G. Sobey, Thiruma V. Arumugam, Christopher P. Chen, Mitchell K. P. Lai
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-23 (2023)
Abstract Vascular cognitive impairment (VCI) describes a wide spectrum of cognitive deficits related to cerebrovascular diseases. Although the loss of blood flow to cortical regions critically involved in cognitive processes must feature as the main
Externí odkaz:
https://doaj.org/article/04bdcb4ece6c4c74836318eba6c538d7
Autor:
Vivian Tran, T. Michael De Silva, Christopher G. Sobey, Kyungjoon Lim, Grant R. Drummond, Antony Vinh, Maria Jelinic
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Metabolic syndrome is characterized by visceral obesity, dyslipidemia, hyperglycemia and hypertension, and affects over one billion people. Independently, the components of metabolic syndrome each have the potential to affect the endothelium to cause
Externí odkaz:
https://doaj.org/article/9fa62f7bf1004d5ba205205e143f6f4b
Autor:
Quynh Nhu Dinh, Cecilia De Silva, David Zhang, Henry Diep, Shenpeng R Zhang, Liz J Barreto Arce, Antony Vinh, Thiruma V Arumugam, Rebecca Lim, Grant R Drummond, Christopher G Sobey, T. Michael De Silva
Publikováno v:
Physiology. 38
Introduction: Vascular stiffening and inflammation are hallmarks of hypertension and contribute to the development of cardiovascular disease and cognitive impairment. Current treatments for hypertension may reduce blood pressure but do not target the
Autor:
David E. Wong Zhang, Vivian Tran, Antony Vinh, Quynh Nhu Dinh, Grant R. Drummond, Christopher G. Sobey, Maria Jelinic, T. Michael De Silva
Publikováno v:
NeuroMolecular Medicine.
Obesity is a major global health concern, with prevalence rates rapidly rising due to increased availability of highly processed foods rich in fats and/or sugars and technological advances promoting more sedentary behaviour. There is increasing evide
Autor:
Gerard Pernes, Poorane Morgan, Kevin Huynh, Corey Giles, Sudip Paul, Alex Smith, Natalie Mellett, Camilla Bertuzzo-Veiga, Thomas Collins, Michael De silva, Man Lee, Peter Meikle, Graeme Lancaster, Andrew Murphy
The cellular lipidome is comprised of thousands of unique lipid species. Herein, using mass spectrometry-based targeted lipidomics we have characterized the lipid landscape of human and mouse immune cells (www.cellularlipidatlas.com). Using this reso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ac5adfed799d5ca78c20a40aa82a682
https://doi.org/10.21203/rs.3.rs-2689702/v1
https://doi.org/10.21203/rs.3.rs-2689702/v1
Autor:
Gerard Pernes, Pooranee K Morgan, Kevin Huynh, Corey Giles, Sudip Paul, Adam Alexander T Smith, Natalie A Mellett, Camilla Bertuzzo Veiga, Thomas JC Collins, T Michael De Silva, Man KS Lee, Peter J Meikle, Graeme I Lancaster, Andrew J Murphy
The cellular lipidome is comprised of thousands of unique lipid species. This complexity underpins the many roles of lipids in cellular biology. How lipidome composition varies between cell types and how such differences contribute to cell-specific f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::655ad93c6f4343317ce82a95c9c91bfb
https://doi.org/10.1101/2023.02.10.528075
https://doi.org/10.1101/2023.02.10.528075
Autor:
Vismitha Rajeev, David Y. Fann, Quynh Nhu Dinh, Hyun Ah Kim, T. Michael De Silva, Mitchell K.P. Lai, Christopher Li-Hsian Chen, Grant R. Drummond, Christopher G. Sobey, Thiruma V. Arumugam
Publikováno v:
Theranostics. 12:1639-1658
The prevalence of cerebrovascular disease increases with age, placing the elderly at a greater lifetime risk for dementia. Vascular cognitive impairment (VCI) encompasses a spectrum of cognitive deficits from mild cognitive impairment to dementia. VC
Autor:
Vismitha Rajeev, David Y. Fann, Quynh Nhu Dinh, Hyun Ah Kim, T. Michael De Silva, Dong-Gyu Jo, Grant R. Drummond, Christopher G. Sobey, Mitchell K.P. Lai, Christopher Li-Hsian Chen, Thiruma V. Arumugam
Publikováno v:
International Journal of Biological Sciences. 18:6052-6067
Autor:
T. Michael De Silva, Frank M. Faraci
Publikováno v:
Methods in Molecular Biology ISBN: 9781071629253
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64f42e8acd2782e0148bf383415ddaa4
https://doi.org/10.1007/978-1-0716-2926-0_34
https://doi.org/10.1007/978-1-0716-2926-0_34