Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Michael David Goodyear"'
Autor:
Corinne Leroi, Zadeo Cimarosti, Stefano Provera, Michael David Goodyear, Giuseppe Guercio, Marie Hourdin, Francesco Tinazzi, Ilaria Bientinesi, Alcide Perboni, Sergio Bacchi, Stefano Curti
Publikováno v:
Organic Process Research & Development. 13:1100-1110
GW597599 1 is a novel NK-1 antagonist currently under investigation for the treatment of central nervous system disorders and emesis. The initial chemical development synthetic route, derived from the one used by medicinal chemistry, involved several
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::158b1f3c2b768396431325a7047235d2
https://doi.org/10.1021/op9002032
https://doi.org/10.1021/op9002032
Autor:
Stefano Provera, Stefano Curti, Michael David Goodyear, Sergio Bacchi, Giuseppe Guercio, Angelo M. Manzo
Publikováno v:
Organic Process Research & Development. 13:489-493
GW597599 1 is a novel NK-1 antagonist currently under investigation for the treatment of CNS disorders and emesis. The initial chemical development synthetic route, derived from the one used by medicinal chemistry, involved several hazardous reagents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b67e486d53fc4e177c8209393d75bc97
https://doi.org/10.1021/op8002823
https://doi.org/10.1021/op8002823
Autor:
Michael David Goodyear, Whitehead Andrew Jonathan, Latham William David Stuart, Mark J. Coleman
Publikováno v:
ChemInform. 31
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17ddbb2e8b129f8bbf77c7cb75fa8207
https://doi.org/10.1002/chin.200012095
https://doi.org/10.1002/chin.200012095
Publikováno v:
ChemInform. 37
A practical enantioselective synthesis of lamivudine 1 is described. A highly effective dynamic kinetic resolution of the 5-hydroxyoxathiolane, followed by chlorination and introduction of cytosine provides an efficient synthesis of lamivudine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c71a8d1036852d8835edadba1d048a03
https://doi.org/10.1002/chin.200612225
https://doi.org/10.1002/chin.200612225
Autor:
Latham William David Stuart, Whitehead Andrew Jonathan, Mark J. Coleman, Michael David Goodyear
Publikováno v:
Synlett. 1999:1923-1924
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b27096d30f382236f64edd8975df04b
https://doi.org/10.1055/s-1999-2978
https://doi.org/10.1055/s-1999-2978