Zobrazeno 1 - 10
of 250
pro vyhledávání: '"Michael D. Schneider"'
Autor:
Sarah Bowling, Aida Di Gregorio, Margarida Sancho, Sara Pozzi, Marieke Aarts, Massimo Signore, Michael D. Schneider, Juan Pedro Martinez-Barbera, Jesús Gil, Tristan A. Rodríguez
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
During embryo development, cell fitness determines survival but how this is regulated is unclear. Here, the authors show that in early embryonic development and stem cells exiting the naive state, cells sense the fitness of their neighbours and trigg
Externí odkaz:
https://doaj.org/article/fa84dfb29e394c458e23e23541902818
Autor:
Jun Fujita, Pablo Freire, Cristian Coarfa, Ashley L. Benham, Preethi Gunaratne, Michael D. Schneider, Marion Dejosez, Thomas P. Zwaka
Publikováno v:
Cell Reports, Vol 21, Iss 6, Pp 1562-1573 (2017)
Summary: Ronin (THAP11), a DNA-binding protein that evolved from a primordial DNA transposon by molecular domestication, recognizes a hyperconserved promoter sequence to control developmentally and metabolically essential genes in pluripotent stem ce
Externí odkaz:
https://doaj.org/article/5b8baf19bb9b4b479027cec034bfbe8d
Autor:
Alessondra T. Speidel, Daniel J. Stuckey, Lesley W. Chow, Laurence H. Jackson, Michela Noseda, Marta Abreu Paiva, Michael D. Schneider, Molly M. Stevens
Publikováno v:
ACS Central Science, Vol 3, Iss 4, Pp 338-348 (2017)
Externí odkaz:
https://doaj.org/article/f2f478710f3d4e048a4614a319bc5f01
Autor:
Muneer G. Hasham, Nicoleta Baxan, Daniel J. Stuckey, Jane Branca, Bryant Perkins, Oliver Dent, Ted Duffy, Tolani S. Hameed, Sarah E. Stella, Mohammed Bellahcene, Michael D. Schneider, Sian E. Harding, Nadia Rosenthal, Susanne Sattler
Publikováno v:
Disease Models & Mechanisms, Vol 10, Iss 3, Pp 259-270 (2017)
Systemic autoimmune diseases such as systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) show significant heart involvement and cardiovascular morbidity, which can be due to systemically increased levels of inflammation or direct autorea
Externí odkaz:
https://doaj.org/article/bb2f7d4f37da469ba72bd96e0fc352f8
Autor:
Gabor Földes, Elena Matsa, János Kriston-Vizi, Thomas Leja, Stefan Amisten, Ljudmila Kolker, Thusharika Kodagoda, Nazanin F. Dolatshad, Maxime Mioulane, Karine Vauchez, Tamás Arányi, Robin Ketteler, Michael D. Schneider, Chris Denning, Sian E. Harding
Publikováno v:
Stem Cell Reports, Vol 3, Iss 5, Pp 905-914 (2014)
Cardiomyocytes from human embryonic stem cells (hESC-CMs) and induced pluripotent stem cells (hiPSC-CMs) represent new models for drug discovery. Although hypertrophy is a high-priority target, we found that hiPSC-CMs were systematically unresponsive
Externí odkaz:
https://doaj.org/article/529d5f740e75416a8884f6be832a7c7d
Autor:
Bjarki Johannesson, Susanne Sattler, Ekaterina Semenova, Saveria Pastore, Teresa M. Kennedy-Lydon, Robert D. Sampson, Michael D. Schneider, Nadia Rosenthal, Daniel Bilbao
Publikováno v:
Disease Models & Mechanisms, Vol 7, Iss 8, Pp 977-985 (2014)
Allergic contact dermatitis (ACD) is triggered by an aberrant hyperinflammatory immune response to innocuous chemical compounds and ranks as the world’s most prevalent occupational skin condition. Although a variety of immune effector cells are act
Externí odkaz:
https://doaj.org/article/e0cb2a63b9b5411ea3934b07974efada
Autor:
Sarah Bowling, Aida Di Gregorio, Margarida Sancho, Sara Pozzi, Marieke Aarts, Massimo Signore, Michael D. Schneider, Juan Pedro Martinez-Barbera, Jesús Gil, Tristan A. Rodríguez
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
The original version of this article contained an error in the spelling of Juan Pedro Martinez-Barbera, which was incorrectly given as Juan Pedro Martinez Barbera. This error has now been corrected in both the PDF and HTML versions of the Article.
Externí odkaz:
https://doaj.org/article/d9d3e8655f944953bb7cd95e65f8e4b7
Autor:
Enrique Gallego-Colon, Robert D. Sampson, Susanne Sattler, Michael D. Schneider, Nadia Rosenthal, Joanne Tonkin
Publikováno v:
Mediators of Inflammation, Vol 2015 (2015)
Strategies to limit damage and improve repair after myocardial infarct remain a major therapeutic goal in cardiology. Our previous studies have shown that constitutive expression of a locally acting insulin-like growth factor-1 Ea (IGF-1Ea) propeptid
Externí odkaz:
https://doaj.org/article/2286de72fc804cbea58e83ee14cb5a62
Autor:
Jose A. Palacios, Michael D. Schneider
Publikováno v:
EMBO Molecular Medicine, Vol 5, Iss 2, Pp 177-179 (2013)
Externí odkaz:
https://doaj.org/article/2d4fb5f06d5c4113b73b033ce03cc95c
Autor:
Antonio M. A. Miranda, Vaibhao Janbandhu, Henrike Maatz, Kazumasa Kanemaru, James Cranley, Sarah A. Teichmann, Norbert Hübner, Michael D. Schneider, Richard P. Harvey, Michela Noseda
Publikováno v:
Nature Reviews Cardiology. 20:289-308
Cardiovascular disease is the leading cause of death globally. An advanced understanding of cardiovascular disease mechanisms is required to improve therapeutic strategies and patient risk stratification. State-of-the-art, large-scale, single-cell an