Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Michael D. Rokaw"'
Publikováno v:
American Journal of Physiology-Cell Physiology. 274:C1245-C1252
We have confirmed that A6 cells (derived from kidney of Xenopus laevis), which contain both mineralocorticoid and glucocorticoid receptors, do not normally possess 11β-hydroxysteroid dehydroxgenase (11β-HSD1 or 11β-HSD2) enzymatic activity and so
Autor:
Michael D. Rokaw, Paul M. Palevsky, Sonia A. Cunningham, Dale J. Benos, Michael E. West, John P. Johnson
Publikováno v:
Journal of Biological Chemistry. 271:4491-4496
The action of aldosterone to increase apical membrane permeability in responsive epithelia is thought to be due to activation of sodium channels. This channel is regulated, in part, by G-proteins, but it is not known if this mechanism is regulated by
Publikováno v:
The American journal of physiology. 277(4)
The enzyme phosphatidylinositide 3-kinase (PI3K) phosphorylates the D-3 position of the inositol ring of inositol phospholipids and produces 3-phosphorylated inositides. These novel second messengers are thought to mediate diverse cellular signaling
Autor:
Jun-Min Wang, Daniel Hui, Vadim Shlyonsky, Robert S. Edinger, Michael D. Rokaw, Dale J. Benos, Iskander I. Ismailov, Bakhrom K. Berdiev, Pamela Middleton, John P. Johnson, Douglas C. Eaton, Ora A. Weisz
Publikováno v:
The Journal of biological chemistry. 273(44)
The action of aldosterone to increase apical membrane permeability in responsive epithelia is thought to be due to activation of sodium channels. Aldosterone stimulates methylation of a 95-kDa protein in apical membrane of A6 cells, and we have previ
Publikováno v:
The Journal of biological chemistry. 271(50)
Rapamycin and FK506 have unique cellular effects despite the fact that they bind to the same set of immunophilins, the FK506 binding proteins (FKBP). We have previously reported that rapamycin (RAP) stimulates sodium transport in A6 cells. FK506 did
Autor:
Mark L. Zeidel, E. Lechman, E. Sarac, John P. Johnson, J. Angeski, Michael West, Michael D. Rokaw
Publikováno v:
The American journal of physiology. 270(2 Pt 1)
In several settings in vivo, prolonged inhibition of apical Na+ entry reduces and prolonged stimulation of apical entry enhances the ability of renal epithelial cells to reabsorb Na+, an important feature of the load-dependent regulation of renal tub