Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Michael D. Miyamoto"'
Publikováno v:
Neuropharmacology. 45:691-701
One of the consequences of G-protein-coupled receptor activation is stimulation of phosphoinositol metabolism, leading to the generation of IP3 and its metabolites 1,3,4,5-tetrakisphosphate (IP4) and inositol 1,2,3,4,5,6-hexakisphosphate (IP6). Previ
Publikováno v:
British Journal of Pharmacology. 137:719-727
The role of calmodulin (CaM) in transmitter release was investigated using liposomes to deliver CaM and monoclonal antibodies against CaM (antiCaM) directly into the frog motor nerve terminal. Miniature endplate potentials (MEPPs) were recorded in a
Publikováno v:
Europe PubMed Central
We investigated the effects of angiotensinogen (Ang), angiotensin I (Ang I), and angiotensin II (Ang II) on the fluidity of phosphatidylcholine vesicles. Changes in fluidity were assessed by changes in anisotropy values calculated from fluorescence p
Autor:
Michael D. Miyamoto, Spencer D. Provan
Publikováno v:
Neuroscience Letters. 185:187-190
The effects of Hg 2+ , methyl mercury, and flufenamic acid, all of which inhibit mitochondria, were examined at frog motor nerve terminals. Unbiased estimates of m (no. of transmitter quanta released), n (no. of functional release sites), p (probabil
Autor:
Spencer D. Provan, Michael D. Miyamoto
Publikováno v:
NeuroReport. 3:101-104
The mechanism by which ionic lanthanum (La3+) increases and subsequently decreases spontaneous transmitter release was investigated by recording miniature endplate potentials (MEPPs) at frog neuromuscular junctions. Addition of tetrodotoxin and Co2+
Autor:
Michael D. Miyamoto, Spencer D. Provan
Publikováno v:
Neuroscience Letters. 123:127-130
The effect of 1,2,3,4-tetrahydro-9-aminoacridine (THA) on quantal transmitter release was examined at the frog neuromuscular junction. THA (3 microM) caused an increase in m (no. of quanta released) as measured by K(+)-evoked miniature endplate poten
Autor:
Michael D. Miyamoto, Robert L. Volle
Publikováno v:
Proceedings of the National Academy of Sciences. 71:1489-1492
In the endplates of rat phrenic nerve-diaphragm, application of the acetylcholine-like compound, carbachol, causes a marked increase in transmitter release, as measured electrophysiologically using miniature endplate potential frequency. Washing out
Publikováno v:
The Journal of General Physiology
The frequency of miniature endplate potentials (mepps) in rat diaphragms was markedly increased by epinephrine and norepinephrine in preparations exposed to 15 mM K+. The effect was rapid in onset but gradually declined during continued exposure to t
Autor:
Michael D. Miyamoto
Publikováno v:
Journal of Theoretical Biology. 123:289-304
The release of transmitter occurs in discrete quantal units, such that the number released (m) is equal to the number available (n) times the average probability of release (p). Although a common method of estimating these parameters is to use simple
Autor:
Michael D. Miyamoto
Publikováno v:
Brain research. 267(2)
At motor nerve terminals, Hg 2+ causes (a) irreversible depolarization, (b) increase in transmitter release, and (c) subsequent irreversible block of transmitter release. All effects are antagonized when a Na channel blocker (tetrodotoxin, TTX) and a