Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Michael D. Mendenhall"'
Autor:
Hilaree N. Frazier, Adam O. Ghoweri, Katie L. Anderson, Ruei-Lung Lin, Gabriel J. Popa, Michael D. Mendenhall, Lawrence P. Reagan, Rolf J. Craven, Olivier Thibault
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Insulin signaling is an integral component of healthy brain function, with evidence of positive insulin-mediated alterations in synaptic integrity, cerebral blood flow, inflammation, and memory. However, the specific pathways targeted by this peptide
Externí odkaz:
https://doaj.org/article/108ef5f7b99a485f8df3e416639cbc0c
Autor:
Olivier Thibault, Katie L. Anderson, Adam O. Ghoweri, Gabriel J. Popa, Tara R Hawkinson, Michael D. Mendenhall, Christopher M. Norris, Hilaree N. Frazier, Ruei-Lung Lin, Pradoldej Sompol
Publikováno v:
Aging Cell
As demonstrated by increased hippocampal insulin receptor density following learning in animal models and decreased insulin signaling, receptor density, and memory decline in aging and Alzheimer's diseases, numerous studies have emphasized the import
Autor:
Sidney W. Whiteheart, Qing Jun Wang, Yunjie Huang, Thein Myint, Meenakshi Banerjee, Gabriel J. Popa, Michael D. Mendenhall, Beth A. Garvy, Smita Joshi
Publikováno v:
Arterioscler Thromb Vasc Biol
Objective: Thrombocytopenia is associated with many viral infections suggesting virions interact with and affect platelets. Consistently, viral particles are seen inside platelets, and platelet activation markers are detected in viremic patients. In
Autor:
Christopher M. Norris, Adam O. Ghoweri, Kaia K. Hampton, Michael D. Mendenhall, Susan D. Kraner, Olivier Thibault, Katie L. Anderson, Gabriel J. Popa, Rolf J. Craven, Hilaree N. Frazier, Shaniya Maimaiti
Publikováno v:
Neurochemical Research. 44:269-280
Memory and cognitive decline are the product of numerous physiological changes within the aging brain. Multiple theories have focused on the oxidative, calcium, cholinergic, vascular, and inflammation hypotheses of brain aging, with recent evidence s
Autor:
Martin K. Nielsen, David W. Rodgers, Paul Slusarewicz, Christopher Mills, Gabriel J. Popa, K. Martin Chow, Stefanie Pagano, Michael D. Mendenhall
Publikováno v:
International journal for parasitology. 46(8)
Intestinal parasites are a concern in veterinary medicine worldwide and for human health in the developing world. Infections are identified by microscopic visualisation of parasite eggs in faeces, which is time-consuming, requires technical expertise
Autor:
Michael D. Mendenhall, Timothy D. Cummins, David W. Powell, Syed J. Khundmiri, Jon B. Klein, Erik A. Korte, Michelle T. Barati, Michelle N. Lowry, Sarah A. Salyer
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1814:1748-1757
Notch proteins (Notch 1-4) are a family of trans-membrane cell surface receptors that are converted into transcriptional regulators when activated by interactions with cell surface ligands on adjacent cells. Ligand-binding stimulates proteolytic clea
Autor:
Clare H Latta, Erica M. Weekman, Tiffany L. Sudduth, Kaitlyn Braun, Gabriel J. Popa, Floracita Gonzalez-Oregon, Erin L. Abner, Michael D. Mendenhall, Donna M. Wilcock
Publikováno v:
Journal of Neuroinflammation
Background Microglia are considered the resident immune cells of the central nervous system (CNS). In response to harmful stimuli, an inflammatory reaction ensues in which microglia are activated in a sequenced spectrum of pro- and antiinflammatory p
Publikováno v:
Infection and Immunity. 69:5752-5759
Cytolethal distending toxins (CDTs) are multisubunit proteins produced by a variety of bacterial pathogens that cause enlargement, cell cycle arrest, and apoptosis in mammalian cells. While their function remains uncertain, recent studies suggest tha
Autor:
Michael D. Mendenhall, Amy Hodge
Publikováno v:
Molecular and General Genetics MGG. 262:55-64
By inhibiting the activity of Cdc28/Clb cyclin-dependent protein kinase (CDK) complexes, Sic1 prevents the premature initiation of S phase in the yeast Saccharomyces cerevisiae. By testing a series of Sic1 truncation mutants, we have mapped the minim
Autor:
Curt Wittenberg, E.Elizabeth Patton, Stefan Lanker, Brandt L. Schneider, Bruce Futcher, Mike Tyers, Michael D. Mendenhall
Publikováno v:
Nature. 395:86-89
In most eukaryotes, commitment to cell division occurs in late G1 phase at an event called Start in the yeast Saccharomyces cerevisiae, and called the restriction point in mammalian cells. Start is triggered by the cyclin-dependent kinase Cdc28 and t