Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Michael D. M. Dryden"'
Autor:
Julian Lamanna, Erica Y. Scott, Harrison S. Edwards, M. Dean Chamberlain, Michael D. M. Dryden, Jiaxi Peng, Barbara Mair, Adam Lee, Calvin Chan, Alexandros A. Sklavounos, Austin Heffernan, Farhana Abbas, Charis Lam, Maxwell E. Olson, Jason Moffat, Aaron R. Wheeler
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Multi-Omic approaches are a powerful way for obtaining in-depth understanding of a cell’s state. Here the authors present DISCO, combining digital microfluidics, laser cell lysis, and artificial intelligence-driven image processing to analyze singl
Externí odkaz:
https://doaj.org/article/f14d36deac8249f8ad452834eda79d88
Autor:
Harrison Edwards, Julian Lamanna, Jason Moffat, Charis Lam, Barbara Mair, Austin Heffernan, Maxwell E. Olson, Farhana Abbas, Jiaxi Peng, Michael D. M. Dryden, Calvin C. H. Chan, Aaron R. Wheeler, Alexandros A. Sklavounos, M. Dean Chamberlain, Erica Y. Scott, Adam Lee
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications
Nature Communications
We introduce Digital microfluidic Isolation of Single Cells for -Omics (DISCO), a platform that allows users to select particular cells of interest from a limited initial sample size and connects single-cell sequencing data to their immunofluorescenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9b3ae1bafe8cd9bdab4a150fa3d5b3d
http://link.springer.com/article/10.1038/s41467-020-19394-5
http://link.springer.com/article/10.1038/s41467-020-19394-5
Autor:
Michael D M Dryden, Aaron R Wheeler
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140349 (2015)
Most electroanalytical techniques require the precise control of the potentials in an electrochemical cell using a potentiostat. Commercial potentiostats function as "black boxes," giving limited information about their circuitry and behaviour which
Externí odkaz:
https://doaj.org/article/6ee63d954ec24dbd9ac12f4551f9374c
Autor:
Yen Leung, Mohtashim H. Shamsi, Yue Yu, Michael D. M. Dryden, Dimitar L. Krastev, Aaron R. Wheeler
Publikováno v:
Lab on a Chip. 16:543-552
Dopamine (DA) is a classical neurotransmitter and dysfunction in its synaptic handling underlies many neurological disorders, including addiction, depression, and neurodegeneration. A key to understanding DA dysfunction is the accurate measurement of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb32889a2a087c1858a3e8e5cc24c083
https://doi.org/10.1039/c5lc01515d
https://doi.org/10.1039/c5lc01515d
Autor:
Edward A. Sykes, Alaine Knipes, Nina Marano, Paul M. Chege, Peter Borus, Charis Lam, Maurice Ope, Rosemary Nzunza, Ngina Kisangau, Christopher Dixon, Darius G. Rackus, Eugene Lam, Michael D. M. Dryden, M. Dean Chamberlain, Ryan Fobel, Christian Fobel, Alphonsus H. C. Ng, Paul A. Rota, Mohd Afiq Mohd Asri, Victor Lee, John Wagacha Burton, John Kiogora, Aaron R. Wheeler, Man Ho, Aimee Summers, Heather M. Scobie, Michael Karuingi, Rachael Joseph, Nooman S. Mufti, Julian Lamanna, Mary Njuguna
Publikováno v:
Science Translational Medicine. 10
Serosurveys are useful for assessing population susceptibility to vaccine-preventable disease outbreaks. Although at-risk populations in remote areas could benefit from this type of information, they face several logistical barriers to implementation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c270a747259421ba7c3169ec2ca55baa
https://doi.org/10.1126/scitranslmed.aar6076
https://doi.org/10.1126/scitranslmed.aar6076
Autor:
Alexandre Zaragoza, Brian Lam, Julian Lamanna, Darius G. Rackus, Michael D. M. Dryden, Aaron R. Wheeler, Shana O. Kelley
Publikováno v:
Lab on a Chip. 15:3776-3784
Nanostructured microelectrodes (NMEs) are three-dimensional electrodes that have superb sensitivity for electroanalysis. Here we report the integration of NMEs with the versatile fluid-handling system digital microfluidics (DMF), for eventual applica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6657944fda7d1f5e1cf01b35c440a18
https://doi.org/10.1039/c5lc00660k
https://doi.org/10.1039/c5lc00660k
Publikováno v:
Analytical chemistry. 89(8)
Isaac Newton famously observed that “if I have seen further it is by standing on the shoulders of giants.” We propose that this sentiment is a powerful motivation for the “open-source” movement in scientific research, in which creators provid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bdde6bcb8dcaeae755e5e554db4866a
https://pubmed.ncbi.nlm.nih.gov/28379683
https://pubmed.ncbi.nlm.nih.gov/28379683
Autor:
Michael Fey, Ian Swyer, Werner E. Maas, André J. Simpson, Aaron R. Wheeler, Michael D. M. Dryden, Ronald Soong
Publikováno v:
Lab on a chip. 16(22)
Nuclear magnetic resonance (NMR) spectroscopy is extremely powerful for chemical analysis but it suffers from lower mass sensitivity compared to many other analytical detection methods. NMR microcoils have been developed in response to this limitatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f174e6e6b47eaf49bfd0ab7eb389dc8f
https://pubmed.ncbi.nlm.nih.gov/27757467
https://pubmed.ncbi.nlm.nih.gov/27757467
Autor:
Jared M. Mudrik, Andrei K. Yudin, Kaixiang Lin, Aaron R. Wheeler, Mais J. Jebrail, Naila Assem, Michael D. M. Dryden
Publikováno v:
Journal of Flow Chemistry. 2:103-107
A microfluidic technique for combinatorial chemical synthesis of peptidomimetics has been developed. The new method is fast, automated and includes an integrated magnetic separation of inorganic catalysts from reaction products. This proof-of-concept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::017aabdb2137d067ba033e07dcd101ca
https://doi.org/10.1556/jfc-d-12-00012
https://doi.org/10.1556/jfc-d-12-00012
Publikováno v:
Analytical chemistry. 85(18)
Digital microfluidics (DMF) is an emerging technique for manipulating small volumes of liquids. DMF is particularly well suited for analytical applications as it allows automated handling of discrete samples, and it has been integrated with several i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53a378331f29a026b7ac36dbcb891b3d
https://pubmed.ncbi.nlm.nih.gov/24001207
https://pubmed.ncbi.nlm.nih.gov/24001207