Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Michael D. Kruppa"'
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 6 (2023)
ABSTRACT Candida albicans is part of normal microbiota; however, it can cause superficial and life-threatening infections in immune-compromised individuals. As the use of drugs from the echinocandin (ECN) class for the treatment of candidiasis is inc
Externí odkaz:
https://doaj.org/article/82691a61fba941f7aad9bc5069b7a97b
Autor:
Jian Miao, Jessica Regan, Chun Cai, Glen E. Palmer, David L. Williams, Michael D. Kruppa, Brian M. Peters
Publikováno v:
mBio, Vol 14, Iss 2 (2023)
ABSTRACT The polymorphic fungus Candida albicans remains a leading cause of both invasive and superficial mycoses, including vulvovaginal candidiasis (VVC). Metabolic plasticity, including carbohydrate catabolism, confers fitness advantages at anatom
Externí odkaz:
https://doaj.org/article/1de41200d62b4cc183dadf2e409c26eb
Autor:
Douglas W. Lowman, M. Sameer Al-Abdul-Wahid, Zuchao Ma, Michael D. Kruppa, Elena Rustchenko, David L. Williams
Publikováno v:
The Cell Surface, Vol 7, Iss , Pp 100061- (2021)
The fungal cell wall serves as the interface between the organism and its environment. Complex carbohydrates are a major component of the Candida albicans cell wall, i.e., glucan, mannan and chitin. β-Glucan is a pathogen associated molecular patter
Externí odkaz:
https://doaj.org/article/930a51ab97884630949558c70dbfec5c
Autor:
Mark V. Horton, Chad J. Johnson, Robert Zarnowski, Brody D. Andes, Taylor J. Schoen, John F. Kernien, Douglas Lowman, Michael D. Kruppa, Zuchao Ma, David L. Williams, Anna Huttenlocher, Jeniel E. Nett
Publikováno v:
mSphere, Vol 6, Iss 3 (2021)
The emerging fungal pathogen Candida auris
Externí odkaz:
https://doaj.org/article/60c29a0578ed4e0d8df13d3f69f173c0
Autor:
Darren Leahy, Cameron Grant, Alex Jackson, Alex Duff, Nicholas Tardiota, Jessica Van Haeften, Xingchen Chen, Jonathan M. Peake, Michael D. Kruppa, Eliot T. Smith, David A. Johnson, William B. Lott, Jonathan M. Harris
Publikováno v:
Molecules, Vol 26, Iss 17, p 5344 (2021)
Human neutrophil elastase (HNE) is a uniquely destructive serine protease with the ability to unleash a wave of proteolytic activity by destroying the inhibitors of other proteases. Although this phenomenon forms an important part of the innate immun
Externí odkaz:
https://doaj.org/article/06c08418647744e288d41d3b67a423b3
Autor:
Michael D. Kruppa, Jeremy Jacobs, Kelsey King-Hook, Keleigh Galloway, Amy Berry, Jennifer Kintner, Judy D. Whittimore, Rolf Fritz, Robert V. Schoborg, Jennifer V. Hall
Publikováno v:
Frontiers in Microbiology, Vol 9 (2019)
Microbial interactions represent an understudied facet of human health and disease. In this study, the interactions that occur between Chlamydia trachomatis and the opportunistic fungal pathogen, Candida albicans were investigated. Candida albicans i
Externí odkaz:
https://doaj.org/article/6c7869dacc8240eeae059dffb9d5086f
Autor:
Sudisht K. Sah, Soumyaroop Bhattacharya, Anshuman Yadav, Farha Husain, Aissatou B. K. T. Ndiaye, Michael D. Kruppa, Jeffrey J. Hayes, Elena Rustchenko
Publikováno v:
Antimicrob Agents Chemother
Candida albicans is an opportunistic human fungal pathogen that causes invasive infections in immunocompromised individuals. Despite the high anticandidal activity among the echinocandins (ECNs), a first-line therapy, resistance remains an issue. Fur
Autor:
Michael D, Kruppa, Douglas W, Lowman, Harry E, Ensley, Zuchao, Ma, Bridget, Graves, Jennifer, Kintner, Jennifer V, Hall, Tammy R, Ozment, David L, Williams
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2542
The cell wall contains mannans and glucans that are recognized by the host immune system. In this chapter, we will describe the methods to isolate mannans and glucans from the C. albicans cell wall. In addition, we describe how to determine purity, m
Autor:
Michael D. Kruppa, Douglas W. Lowman, Harry E. Ensley, Zuchao Ma, Bridget Graves, Jennifer Kintner, Jennifer V. Hall, Tammy R. Ozment, David L. Williams
Publikováno v:
Methods in Molecular Biology ISBN: 9781071625484
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80961c07d0b59ae2345bf0ee6c9e6e22
https://doi.org/10.1007/978-1-0716-2549-1_24
https://doi.org/10.1007/978-1-0716-2549-1_24
Autor:
David A. Johnson, Cameron Grant, Xingchen Chen, Alex Jackson, Eliot T Smith, William B. Lott, Jonathan M. Peake, Alex Duff, Michael D. Kruppa, Darren Leahy, Jonathan M. Harris, Jessica Van Haeften, Nicholas Tardiota
Publikováno v:
Molecules
Volume 26
Issue 17
Molecules, Vol 26, Iss 5344, p 5344 (2021)
Volume 26
Issue 17
Molecules, Vol 26, Iss 5344, p 5344 (2021)
Human neutrophil elastase (HNE) is a uniquely destructive serine protease with the ability to unleash a wave of proteolytic activity by destroying the inhibitors of other proteases. Although this phenomenon forms an important part of the innate immun