Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Michael D. Hunckler"'
Autor:
Michael D. Hunckler, Aaron D. Levine
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Biomaterials--from implanted iron teeth in the second century to intraocular lenses, artificial joints, and stents today--have long been used clinically. Today, biomaterials researchers and biomedical engineers are pushing beyond these inert syntheti
Externí odkaz:
https://doaj.org/article/3f1f072161084df6b6889c941ad73bb3
Autor:
Juan D, Medina, Graham F, Barber, Maria M, Coronel, Michael D, Hunckler, Stephen W, Linderman, Michelle J, Quizon, Vahap, Ulker, Esma S, Yolcu, Haval, Shirwan, Andrés J, García
Publikováno v:
Journal of Biomedical Materials Research Part A. 110:1728-1737
Type 1 diabetes (T1D), an autoimmune disorder in which the insulin-producing β-cells in the islets of Langerhans in the pancreas are destroyed, afflicts over 1.6 million Americans. Although pancreatic islet transplantation has shown promise in treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22dc73bb240a86158a9c0f510b1b2652
https://doi.org/10.1002/jbm.a.37429
https://doi.org/10.1002/jbm.a.37429
Autor:
Ji Lei, María M. Coronel, Esma S. Yolcu, Hongping Deng, Orlando Grimany-Nuno, Michael D. Hunckler, Vahap Ulker, Zhihong Yang, Kang M. Lee, Alexander Zhang, Hao Luo, Cole W. Peters, Zhongliang Zou, Tao Chen, Zhenjuan Wang, Colleen S. McCoy, Ivy A. Rosales, James F. Markmann, Haval Shirwan, Andrés J. García
Publikováno v:
Science advances. 8(19)
Islet transplantation to treat insulin-dependent diabetes is greatly limited by the need for maintenance immunosuppression. We report a strategy through which cotransplantation of allogeneic islets and streptavidin (SA)–FasL–presenting microgels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aded5a5445852b3a900f73d8700fe42
https://pubmed.ncbi.nlm.nih.gov/35559682
https://pubmed.ncbi.nlm.nih.gov/35559682
Autor:
Marc A. Fernandez-Yague, Alexandra M. Smink, Michael Alexander, Maria M. Coronel, Jonathan R. T. Lakey, Paul de Vos, Michael D. Hunckler, Andrés J. García, Juan D. Medina
Publikováno v:
Advanced healthcare materials, 9(9):2000102. Wiley-Blackwell
Adv Healthc Mater
Advanced healthcare materials, vol 9, iss 9
Adv Healthc Mater
Advanced healthcare materials, vol 9, iss 9
Translation of transplanted alginate-encapsulated pancreatic islets to treat type 1 diabetes has been hindered by inconsistent long-term efficacy. This loss of graft function can be partially attributed to islet dysfunction associated with the destru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f09107923ea8c9ec5fe8f30aa440ab94
https://research.rug.nl/en/publications/ff7bc8c0-09a5-43fb-a408-5f96b19cae50
https://research.rug.nl/en/publications/ff7bc8c0-09a5-43fb-a408-5f96b19cae50
Autor:
Edward A. Botchwey, Maria M. Coronel, Esma S. Yolcu, Lalit Batra, Eric B. O’Neill, Karen E. Martin, Claire McClain, Michael D. Hunckler, Graham Barber, Peng Qiu, Juan D. Medina, Enrico Opri, Jessica D. Weaver, Hong Seo Lim, Haval Shirwan, Andrés J. García
Publikováno v:
Science Advances
Local biomaterial-mediated delivery of PD-L1 induces alloislet graft survival and function in a murine model of type 1 diabetes.
Antibody-mediated immune checkpoint blockade is a transformative immunotherapy for cancer. These same mechanisms can
Antibody-mediated immune checkpoint blockade is a transformative immunotherapy for cancer. These same mechanisms can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86ce37c44326a8eff1782871b1b755f8
https://pubmed.ncbi.nlm.nih.gov/32923626
https://pubmed.ncbi.nlm.nih.gov/32923626
Autor:
Ethan D. Chu, Andrew P. Baumann, Matthew J. Ravosa, Michael D. Hunckler, Ryan K. Roeder, Matthew R. Allen, Tyler E. Curtis
Publikováno v:
Bone. 105:67-74
Small animal models, and especially transgenic models, have become widespread in the study of bone mechanobiology and metabolic bone disease, but test methods for measuring fracture toughness on multiple replicates or at multiple locations within a s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fc4b6819f64886251e90750d36f4763
https://doi.org/10.1016/j.bone.2017.08.015
https://doi.org/10.1016/j.bone.2017.08.015
Autor:
Juan D. Medina, Andrés J. García, Cherie L. Stabler, Jessica D. Weaver, Michael D. Hunckler, Maria M. Coronel
Publikováno v:
Adv Healthc Mater
Thiol-norbornene (thiol-ene) photoclickable poly(ethylene glycol) (PEG) hydrogels are a versatile biomaterial for cell encapsulation, drug delivery, and regenerative medicine. Numerous in vitro studies with these 4-arm ester-linked PEG-norbornene (PE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ead4927faec0436136ddf9bf314cfa62
https://europepmc.org/articles/PMC6658339/
https://europepmc.org/articles/PMC6658339/
Autor:
Maria M. Coronel, Devon M. Headen, Michael D. Hunckler, Haval Shirwan, Jessica D. Weaver, Andrés J. García
Publikováno v:
Am J Transplant
Transplantation of hydrogel-encapsulated allogeneic islets has been explored to reduce or eliminate the need for chronic systemic immunosuppression by creating a physical barrier which prevents direct antigen presentation. Although successful in rode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::840096ed7c6cc706ce010741b8eeab9f
https://europepmc.org/articles/PMC6487074/
https://europepmc.org/articles/PMC6487074/
Autor:
Haiqing Lin, Ruilan Guo, Michael D. Hunckler, Barbara A. Kazanowska, Junyi Liu, Ryan K. Roeder, Shuangjiang Luo
Publikováno v:
Journal of Materials Chemistry A. 4:17050-17062
Polybenzoxazoles (PBOs), such as thermally rearranged (TR) polymers, have been shown to have excellent gas separation performance. Herein we report the preparation and transport properties of two new series of PBO-based polymers that were thermally d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc33e078b3137b04f39e64e97027f231
https://doi.org/10.1039/c6ta03951k
https://doi.org/10.1039/c6ta03951k
Autor:
Andrés J. García, Maria M. Coronel, Jonathan R. T. Lakey, Michael Alexander, Marc A. Fernandez-Yague, Michael D. Hunckler, Juan D. Medina, Alexandra M. Smink, Paul de Vos
Publikováno v:
Advanced Healthcare Materials. 9:2070025
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::272a8a0e832e4314b91ee17a1dc4f2ab
https://doi.org/10.1002/adhm.202070025
https://doi.org/10.1002/adhm.202070025