Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Michael D. Hamilton"'
Autor:
Michael D. Hamilton, David H. Evans
Publikováno v:
Nucleic Acids Research
Poxvirus DNA polymerases play a critical role in promoting virus recombination. To test if vaccinia polymerase (E9L) could mediate this effect by catalyzing the post-synaptic processing of recombinant joint molecules, we prepared substrates bearing a
Publikováno v:
The Journal of Organic Chemistry. 70:967-972
The conjugate additions of (2-piperidyl)acetate esters to acetylenic sulfones, followed by LDA-promoted intramolecular acylations, afforded cyclic enaminones that were readily converted into the corresponding 4-substituted 2-keto- or 2-hydroxyquinoli
Autor:
Thomas G. Back, Michael D. Hamilton
Publikováno v:
ChemInform. 33
The conjugate addition of methyl (S)-(2-piperidyl)acetate (3) to 2-(3,4-dimethoxyphenyl)-1-(p-toluenesulfonyl)ethyne (4), followed by LDA-promoted intramolecular acylation, stereoselective reduction, and desulfonylation, afforded (−)-lasubine II.
A novel mutator locus in Escherichia coli was identified from a collection of random transposon insertion mutants. Several mutators in this collection were found to have an insertion in the dgt gene, encoding a previously characterized dGTP triphosph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aa29cd8f717f1baa420556067ed9277
https://europepmc.org/articles/PMC2580694/
https://europepmc.org/articles/PMC2580694/
Publikováno v:
Nucleic Acids Research
Vaccinia virus DNA polymerase catalyzes duplex-by-duplex DNA joining reactions in vitro and many features of these recombination reactions are reprised in vivo. This can explain the intimate linkage between virus replication and genetic recombination
Publikováno v:
ChemInform. 36
Publikováno v:
Workshop on Software and Performance
The effects of multicast operations on the performance of distributed systems are evaluated by means of approximate expressions for load and delay characteristics. Different strategies for delivering items of information to large numbers of destinati
Publikováno v:
High-Performance Computing and Networking ISBN: 9783540422938
HPCN Europe
HPCN Europe
Web objects are stored in a local cache in order to reduce the cost of future accesses. The cache size is limited, so it is necessary to have a policy for replacing old objects with new ones. This paper examines the problem of constructing optimal or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25e7e2ad905c0cfa34ce5b439e0e6e25
https://doi.org/10.1007/3-540-48228-8_10
https://doi.org/10.1007/3-540-48228-8_10
Autor:
Isi Mitrani, Michael D. Hamilton
Publikováno v:
Computer Performance Evaluation.Modelling Techniques and Tools ISBN: 9783540672609
Computer Performance Evaluation / TOOLS
Computer Performance Evaluation / TOOLS
This paper examines a distributed system where users employ a mobile software agent to perform a sequence of tasks associated with different network nodes. Each operation can be carried out either locally or remotely, and may or may not involve movin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be33b6a2a1c4aa2ae2fe45ac3932505f
https://doi.org/10.1007/3-540-46429-8_11
https://doi.org/10.1007/3-540-46429-8_11
Autor:
Christopher T. Korch, Lucia Liviero, Qi Wang, P. J. Hastings, Charles Steinberg, Christopher J. Tenove, R. C. von Borstel, Micah A Chrenek, R. Gary Ritzel, Grace S.-F. Lee, Ursula G.G. Hennig, Michael D. Hamilton, Robert Tomaszewski, Elizabeth A. Savage, John A. Higgins
Publikováno v:
Genetics. 148(4)
Mutants of the HIS1 locus of the yeast Saccharomyces cerevisiae are suitable reporters for spontaneous reversion events because most reversions are topical, that is, within the locus itself. Thirteen mutations of his1-1 now have been identified with