Zobrazeno 1 - 10
of 245
pro vyhledávání: '"Michael D. Cole"'
Publikováno v:
South African Journal of Science, Vol 117, Iss 11/12 (2021)
Nyaope, a Tswana word for a mixture or ‘mish-mash’, describes a drug cocktail consisting of heroin, cannabis, and on occasion other controlled substances and warfarin. It is highly addictive with extremely unpleasant side effects caused by withdr
Externí odkaz:
https://doaj.org/article/8f2997d6a4e54a5b9c6c8eb5203eb253
Autor:
Ivan P. Gorlov, Claudio W. Pikielny, Hildreth R. Frost, Stephanie C. Her, Michael D. Cole, Samuel D. Strohbehn, David Wallace-Bradley, Marek Kimmel, Olga Y. Gorlova, Christopher I. Amos
Publikováno v:
BMC Bioinformatics, Vol 19, Iss 1, Pp 1-14 (2018)
Abstract Background Because driver mutations provide selective advantage to the mutant clone, they tend to occur at a higher frequency in tumor samples compared to selectively neutral (passenger) mutations. However, mutation frequency alone is insuff
Externí odkaz:
https://doaj.org/article/c7fe5ced7f304ca98c74b3534ff89c04
Autor:
Valeriya Posternak, Michael D. Cole
Publikováno v:
F1000Research, Vol 5 (2016)
MYC is a major driver of cancer cell growth and mediates a transcriptional program spanning cell growth, the cell cycle, metabolism, and cell survival. Many efforts have been made to deliberately target MYC for cancer therapy. A variety of compounds
Externí odkaz:
https://doaj.org/article/e0307b267bf345b7bfc42a0bf6fb2e18
Intravitreal injections (injections into the eye) are a new form of treatment for various conditions such as age-related macular degeneration, diabetic eye disease and vascular eye problems. The use of these injections has become so widespread that m
Publikováno v:
Science & Justice. 63:74-82
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d8a19158614d807b4b6cb05f1c1e755
https://doi.org/10.1016/j.scijus.2022.11.005
https://doi.org/10.1016/j.scijus.2022.11.005
Figure legends for Supplemental Figures 1 and 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45fdeb2c219316552c8f7796af5f7309
https://doi.org/10.1158/1541-7786.22515130
https://doi.org/10.1158/1541-7786.22515130
TFIIH, specifically CDK7, promotes mRNA cap methylation of canonical Wnt/beta-catenin signaling pathway transcripts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cb0ac08707ffc2cd08b1e8eb453666b
https://doi.org/10.1158/1541-7786.22511896
https://doi.org/10.1158/1541-7786.22511896
S1. KLF5 binds the CCNE1 intronic region and contributes to CCNE1 expression in the J82 UBC cell line.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a0ebc8f2d3aba888df9b06a1875089a
https://doi.org/10.1158/1541-7786.22515136
https://doi.org/10.1158/1541-7786.22515136
Description of supplemental data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bee8a4689b331888ac08b57ab7bc1657
https://doi.org/10.1158/1541-7786.22511890.v1
https://doi.org/10.1158/1541-7786.22511890.v1
MYC is a pleiotropic transcription factor that activates and represses a wide range of target genes and is frequently deregulated in human tumors. While much is known about the role of MYC in transcriptional activation and repression, MYC can also re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::151ab2cc3183565a4a947f29904223fe
https://doi.org/10.1158/1541-7786.c.6540070.v1
https://doi.org/10.1158/1541-7786.c.6540070.v1