Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Michael D. Cleary"'
Publikováno v:
Neural Development, Vol 17, Iss 1, Pp 1-13 (2022)
Abstract N6-methyladenosine (m6A) is the most prevalent internal mRNA modification in metazoans and is particularly abundant in the central nervous system. The extent to which m6A is dynamically regulated and whether m6A contributes to cell type-spec
Externí odkaz:
https://doaj.org/article/d1af457eadba43afaa11495ba24debd7
Publikováno v:
Natural Sciences, Vol 2, Iss 1, Pp n/a-n/a (2022)
Abstract Global mRNA translation may differ dramatically between progenitor cells and their differentiated progeny. One way cell type‐specific translation is established is through ribosome concentration. In addition to addressing unique metabolic
Externí odkaz:
https://doaj.org/article/0589b84d61f94f779457f37038a6df89
Publikováno v:
Cell Reports, Vol 24, Iss 7, Pp 1704-1712 (2018)
Summary: Tissue-specific mRNA stability is important for cell fate and physiology, but the mechanisms involved are not fully understood. We found that zygotic mRNA stability in Drosophila correlates with codon content: optimal codons are enriched in
Externí odkaz:
https://doaj.org/article/d329f5098bbd4e6a86dd22b54798e8e6
Publikováno v:
Natural Sciences, Vol 2, Iss 1, Pp n/a-n/a (2022)
Global mRNA translation may differ dramatically between progenitor cells and their differentiated progeny. One way cell type‐specific translation is established is through ribosome concentration. In addition to addressing unique metabolic needs, ch
Autor:
Jade F. Quail, Najwa Alhusaini, Jeff Coller, Dana A. Burow, Michael D. Cleary, Sophie G. Martin
Publikováno v:
Cell reports, vol 24, iss 7
Cell Reports, Vol 24, Iss 7, Pp 1704-1712 (2018)
Cell reports
Cell Reports, Vol 24, Iss 7, Pp 1704-1712 (2018)
Cell reports
SUMMARY Tissue-specific mRNA stability is important for cell fate and physiology, but the mechanisms involved are not fully understood. We found that zygotic mRNA stability in Drosophila correlates with codon content: optimal codons are enriched in s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::effa86bcdc1bde39466bdf0067e5c57c
https://escholarship.org/uc/item/5q60w6pb
https://escholarship.org/uc/item/5q60w6pb
Autor:
Marie Follo, Melanie Boerries, Melissa Zwick, Justus Duyster, Stefanie Kreutmair, Annette Schmitt-Graeff, Anna Lena Illert, Milena Pantic, Cathrin Klingeberg, Irith Baumann, Bernhard Kuster, Hiroyuki Kawaguchi, Detlev Schindler, Khalid Shoumariyeh, Michal Kulinski, Geoffroy Andrieux, Nina Cabezas-Wallscheid, Dietmar Pfeifer, Rouzanna Istvanffy, Robert Zeiser, Martina Rudelius, Alina Rudorf, Miriam Erlacher, Christian Peschel, Michael D. Cleary, Tony Andreas Müller, Christine Dierks, Robert A.J. Oostendorp, Jesus Duque-Afonso, Teresa Poggio, Simone Lemeer, Charlotte M. Niemeyer, Marcin W. Wlodarski, Tamina Rückert
Publikováno v:
Blood. 134:3741-3741
Inherited bone marrow failure syndromes (IBMFS) are a heterogeneous group of disorders characterized by impaired stem cell function resulting in pancytopenia. Diagnosis of IBMFS presents a major challenge due to limited diagnostic tests and overlappi
Autor:
Michael D. Cleary
Publikováno v:
WIREs Developmental Biology. 7
Cell type-specific transcription is a key determinant of cell fate and function. An ongoing challenge in biology is to develop robust and stringent biochemical methods to explore gene expression with cell type specificity. This challenge has become e
Autor:
Samantha Beasley, Dana A. Burow, Michael Fazio, Mohamed Y. Aboukilila, Naoki Hida, Robert C. Spitale, Michael D. Cleary, Rakesh Paul, Marc M. Greenberg
Publikováno v:
Nucleic acids research, vol 45, iss 15
Hida, N; Aboukilila, MY; Burow, DA; Paul, R; Greenberg, MM; Fazio, M; et al.(2017). EC-tagging allows cell type-specific RNA analysis. NUCLEIC ACIDS RESEARCH, 45(15), e138. doi: 10.1093/nar/gkx551. UC Merced: Retrieved from: http://www.escholarship.org/uc/item/6wz9q4w9
Nucleic Acids Research
Hida, N; Aboukilila, MY; Burow, DA; Paul, R; Greenberg, MM; Fazio, M; et al.(2017). EC-tagging allows cell type-specific RNA analysis. NUCLEIC ACIDS RESEARCH, 45(15), e138. doi: 10.1093/nar/gkx551. UC Merced: Retrieved from: http://www.escholarship.org/uc/item/6wz9q4w9
Nucleic Acids Research
Purification of cell type-specific RNAs remains a significant challenge. One solution involves biosynthetic tagging of target RNAs. RNA tagging via incorporation of 4-thiouracil (TU) in cells expressing transgenic uracil phosphoribosyltransferase (UP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::379c09b202dfa02c3366820539599261
https://escholarship.org/uc/item/6wz9q4w9
https://escholarship.org/uc/item/6wz9q4w9