Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Michael D. Brooks"'
Autor:
Ayşe J. Muñiz, Tuğba Topal, Michael D. Brooks, Angela Sze, Do Hoon Kim, Jacob Jordahl, Joe Nguyen, Paul H. Krebsbach, Masha G. Savelieff, Eva L. Feldman, Joerg Lahann
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 10, Iss 7, Pp 1239-1253 (2023)
Abstract Objective Brain organoids are miniaturized in vitro brain models generated from pluripotent stem cells, which resemble full‐sized brain more closely than conventional two‐dimensional cell cultures. Although brain organoids mimic the huma
Externí odkaz:
https://doaj.org/article/b1f6f864b7bc43ee9871a66f7c532eae
Autor:
Tasha Thong, Yutong Wang, Michael D. Brooks, Christopher T. Lee, Clayton Scott, Laura Balzano, Max S. Wicha, Justin A. Colacino
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Similarities between stem cells and cancer cells have implicated mammary stem cells in breast carcinogenesis. Recent evidence suggests that normal breast stem cells exist in multiple phenotypic states: epithelial, mesenchymal, and hybrid epithelial/m
Externí odkaz:
https://doaj.org/article/3d368196c177406e9f920e93f3e5ca04
Autor:
Justin A. Colacino, Ebrahim Azizi, Michael D. Brooks, Ramdane Harouaka, Shamileh Fouladdel, Sean P. McDermott, Michael Lee, David Hill, Julie Madden, Julie Boerner, Michele L. Cote, Maureen A. Sartor, Laura S. Rozek, Max S. Wicha
Publikováno v:
Stem Cell Reports, Vol 10, Iss 5, Pp 1596-1609 (2018)
Summary: During development, the mammary gland undergoes extensive remodeling driven by stem cells. Breast cancers are also hierarchically organized and driven by cancer stem cells characterized by CD44+CD24low/− or aldehyde dehydrogenase (ALDH) ex
Externí odkaz:
https://doaj.org/article/b9efa7a99ce34971b517c5e10fc53566
Autor:
Sophia Orbach, Michael D. Brooks, Grace G. Bushnell, Max S. Wicha, Jacqueline S. Jeruss, Lonnie D. Shea
Publikováno v:
Journal of Clinical and Translational Science, Vol 4, Pp 5-6 (2020)
OBJECTIVES/GOALS: Breast cancer metastases are stochastic and difficult to detect. Therapy is often ineffective due to phenotypic changes of tumor cells at these sites. We engineered a synthetic metastatic niche to study the role of phenotypic transi
Externí odkaz:
https://doaj.org/article/c6dfa113ff9e49869012604e79527314
Autor:
Michael D. Brooks, Richard D. Bennett, Amy L. Weaver, Thomas J. Sebo, Steven E. Eckert, Emanuel E. Strehler, Alan B. Carr
Publikováno v:
International Journal of Dentistry, Vol 2013 (2013)
Oral cancer is often diagnosed only at advanced stages due to a lack of reliable disease markers. The purpose of this study was to determine if the epithelial-specific human calmodulin-like protein (CALML3) could be used as marker for the various pha
Externí odkaz:
https://doaj.org/article/33c26e94d84e42c3b88b3ec605e61823
Publikováno v:
Holland‐Frei Cancer Medicine. :1-12
Autor:
Sophia M. Orbach, Michael D. Brooks, Yining Zhang, Scott E. Campit, Grace G. Bushnell, Joseph T. Decker, Ryan J. Rebernick, Sriram Chandrasekaran, Max S. Wicha, Jacqueline S. Jeruss, Lonnie D. Shea
Publikováno v:
Clin Exp Metastasis
Microenvironmental changes in the early metastatic niche may be exploited to identify therapeutic targets to inhibit secondary tumor formation and improve disease outcomes. We dissected the developing lung metastatic niche in a model of metastatic, t
Autor:
Lonnie D. Shea, Jacqueline S. Jeruss, Max S. Wicha, Michael D. Brooks, Rachel M. Hartfield, Joseph T. Decker, Petrina LaFaire, Matthew S. Hall, Aaron H. Morris, Yining Zhang, Pridvi Kandagatla, Sophia M. Orbach, Grace G. Bushnell, Robert S. Oakes
NCBI GEO formatted submission for OpenArray{trade mark, serif} RT-qPCR data including: ID_REF, Gene Symbol, Reference/Target use, Catalog Number, Assay Type, Gene Name, Alias, RefSeq Accession Number, GenBank mRNA Numbers, Target Species, Amplicon Le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28aaa416a53b182099d125fa71ea4b21
https://doi.org/10.1158/0008-5472.22424434
https://doi.org/10.1158/0008-5472.22424434
Autor:
Lonnie D. Shea, Jacqueline S. Jeruss, Max S. Wicha, Michael D. Brooks, Rachel M. Hartfield, Joseph T. Decker, Petrina LaFaire, Matthew S. Hall, Aaron H. Morris, Yining Zhang, Pridvi Kandagatla, Sophia M. Orbach, Grace G. Bushnell, Robert S. Oakes
Kaplan-Meier survival curves correlated with high and low gene expression from breast cancer patient samples. (a) Microarray (GEO via KMPlot) and prognosis data were queried for genes selected for the 10-gene panel derived from tissue within implants
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::186ff261c4e0f2507913414d51a275ed
https://doi.org/10.1158/0008-5472.22424461
https://doi.org/10.1158/0008-5472.22424461
Autor:
Suling Liu, Max S. Wicha, Zhi-ming Shao, Shawn G. Clouthier, Justin Colacino, Trenton L. Baker, April Davis, Tahra K. Luther, Alex Fox, Li Shang, Michael D. Brooks, Ramdane Harouaka, Shoumin Bai, Joey Guy, Rachel Martin-Trevino, Monika L. Burness, Yajing Liu
Supplementary Figure S1. BRCA1 mutation confirmation and RAD51 gene expression in SUM149 cells. Supplementary Figure S2. RAD51 foci is associated with CSC population of BRCA1-mutant TNBC cells and effect of long-term PARP inhibition on RAD51. Supplem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::219e54e8b76574e7201a32d6b2717780
https://doi.org/10.1158/1078-0432.22460777
https://doi.org/10.1158/1078-0432.22460777