Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Michael D. Bridges"'
Autor:
Zhi Yang, Kim-Marie A. Dam, Michael D. Bridges, Magnus A. G. Hoffmann, Andrew T. DeLaitsch, Harry B. Gristick, Amelia Escolano, Rajeev Gautam, Malcolm A. Martin, Michel C. Nussenzweig, Wayne L. Hubbell, Pamela J. Bjorkman
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Neutralizing antibodies (bNAbs) against HIV-1 are exclusively directed against the viral envelope protein (Env) and mainly target Env in a closed, prefusion state. Here, Yang et al. structurally characterize two heterologously-neutralizing CD4-bindin
Externí odkaz:
https://doaj.org/article/a3f529a3512548c399bdcaadfab62202
Autor:
Peixi-X Wang, Donald G. Fleming, W. A. MacFarlane, Donald J. Arseneau, Mark J. MacLachlan, Michael D. Bridges, Yuanyuan Cao, J Xiao, Robert F. Kiefl
Publikováno v:
The Journal of Physical Chemistry C. 125:21410-21423
Autor:
Kristen A. Gaffney, Ruiqiong Guo, Michael D. Bridges, Shaima Muhammednazaar, Daoyang Chen, Miyeon Kim, Zhongyu Yang, Anthony L. Schilmiller, Nabil F. Faruk, Xiangda Peng, A. Daniel Jones, Kelly H. Kim, Liangliang Sun, Wayne L. Hubbell, Tobin R. Sosnick, Heedeok Hong
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance The conformational properties of denatured states of proteins affect their folding, turnover, translocation, and chaperone action. We find that the denatured state ensemble of a helical membrane protein is richer than depicted in the cla
Autor:
Zhi, Yang, Kim-Marie A, Dam, Michael D, Bridges, Magnus A G, Hoffmann, Andrew T, DeLaitsch, Harry B, Gristick, Amelia, Escolano, Rajeev, Gautam, Malcolm A, Martin, Michel C, Nussenzweig, Wayne L, Hubbell, Pamela J, Bjorkman
Publikováno v:
Nature communications. 13(1)
Broadly-neutralizing antibodies (bNAbs) against HIV-1 Env can protect from infection. We characterize Ab1303 and Ab1573, heterologously-neutralizing CD4-binding site (CD4bs) antibodies, isolated from sequentially-immunized macaques. Ab1303/Ab1573 bin
Autor:
Tobin R. Sosnick, Kristen A. Gaffney, Ruiqiong Guo, Michael D. Bridges, Daoyang Chen, Fathima Shaima MuhammedNazaar, Miyeon Kim, Zhongyu Yang, Anthony L. Schilmiller, Nabil F. Faruk, Xiangda Peng, A.D. Jones, Liangliang Sun, Wayne L. Hubbell, Heedeok Hong
Publikováno v:
Biophysical Journal. 121:469a
Publikováno v:
Applied Magnetic Resonance. 48:1315-1340
Analysis of saturation recovery data from spin-labeled proteins is extended to include the amplitudes in addition to the recovery rates for two-site exchange. It is shown that the recovery amplitudes depend strongly on the exchange rate between state
Autor:
Zhongyu Yang, Steven Y. Qian, Jiajia Rao, James Froberg, Jasmin Farmakes, Michael D. Bridges, Sunanda Neupane, Guodong Liu, Yanxiong Pan, Yongki Choi
Publikováno v:
Nanoscale. 9:3512-3523
Silica nanoparticles (SiNPs) are important nano-sized, solid-state carriers/hosts to load, store, and deliver biological or pharmaceutical cargoes. They are also good potential solid supports to immobilize proteins for fundamental protein structure a
Autor:
Yi Cao, Pei-Xi Wang, Michael D. Bridges, M. H. Dehn, W. A. MacFarlane, Donald G. Fleming, Mark J. MacLachlan, D. J. Arseneau, Vitor de Moraes Zamarion, Robert F. Kiefl, J Xiao
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Gold nanoparticles (AuNPs) have been a subject of considerable interest in recent years due to both their magnetic and catalytic properties. This paper reports a two-fold study of the reactivity at...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daddcffbf1e28160e0fdbac97d4278e4
Autor:
Ruiqiong Guo, Kristen A. Gaffney, Tobin R. Sosnick, Heedeok Hong, Wayne L. Hubbell, Michael D. Bridges, Miyeon Kim
Publikováno v:
Biophysical Journal. 118:27a
Autor:
Robert M. Stroud, Wayne L. Hubbell, Sangwoo S. Kim, Alexander F. Kintzer, Yifan Cheng, Jean Paul Armache, Evan M. Green, Dawid Deneka, Pawel K. Dominik, Michael D. Bridges, Anthony A. Kossiakoff
Publikováno v:
Proceedings of the National Academy of Sciences. 115
Voltage-sensing domains (VSDs) couple changes in transmembrane electrical potential to conformational changes that regulate ion conductance through a central channel. Positively charged amino acids inside each sensor cooperatively respond to changes