Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Michael D. Blower"'
Autor:
Michael D. Blower
Publikováno v:
Cell Reports, Vol 15, Iss 8, Pp 1624-1633 (2016)
Centromeric transcription is widely conserved; however, it is not clear what role centromere transcription plays during mitosis. Here, I find that centromeres are transcribed in Xenopus egg extracts into a long noncoding RNA (lncRNA; cen-RNA) that lo
Externí odkaz:
https://doaj.org/article/12a224e70f69453c8bc4ef8e103ba3a1
Autor:
Filip A. Konopacki, Hovy Ho-Wai Wong, Asha Dwivedy, Anaïs Bellon, Michael D. Blower, Christine E. Holt
Publikováno v:
Open Biology, Vol 6, Iss 4 (2016)
Endocytosis and local protein synthesis (LPS) act coordinately to mediate the chemotropic responses of axons, but the link between these two processes is poorly understood. The endosomal sorting complex required for transport (ESCRT) is a key regulat
Externí odkaz:
https://doaj.org/article/b840736eec2a474caf211487ad2bb95c
Publikováno v:
Molecular Biology of the Cell. 34
The authors investigate inheritance of nuclear RNA by G1 cells following mitosis. They find that multiple pathways regulate differential inheritance of nuclear RNAs.
Mitosis results in a dramatic reorganization of chromatin structure in order to promote chromatin compaction and segregation to daughter cells. Consequently, mitotic entry is accompanied by transcriptional silencing and removal of most chromatin-boun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aef8d12ebb988ab7c5b3acb68b08187d
https://doi.org/10.1101/2022.10.06.511141
https://doi.org/10.1101/2022.10.06.511141
Publikováno v:
Trends Cell Biol
Beyond its originally discovered role tethering replicated sister chromatids, cohesin has emerged as a master regulator of gene expression. Recent advances in chromatin topology resolution and single-cell studies have revealed that cohesin has a pivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f2768137c52f27d7d4f879333333f62
https://europepmc.org/articles/PMC8364472/
https://europepmc.org/articles/PMC8364472/
Autor:
Carlos Villacorta-Martin, Shaghayegh Farhangmehr, Ryan M. Hekman, Mohsan Saeed, Carlos Perea-Resa, Robert A. Davey, Andrew Emili, Jian Zhao, Peter E.A. Ash, Raghuveera Kumar Goel, Benjamin C. Blum, Andrew A. Wilson, Benjamin J. Blencowe, Ulrich Braunschweig, Benjamin Wolozin, Andrew Tilston-Lunel, Darrell N. Kotton, Ji-Xin Cheng, Avik Basu, Alexandra Mora-Martin, Esther Bullitt, Rhiannon B. Werder, Mark E. McComb, Dmitry A. Kretov, Dzmitry Padhorny, Sandeep Ojha, Shawn M. Lyons, Konstantinos D. Alysandratos, Jessie Huang, Anne Hinds, Valentina Perissi, J. J. Patten, Ahmed Youssef, Xaralabos Varelas, John H Connor, Dima Kozakov, Mamta Verma, Dante Bolzan, Indranil Paul, Ellen L Suder, Eric J. Burks, Matthew D. Layne, Elke Mühlberger, Stefan Wuchty, Adam J. Hume, Daniel Cifuentes, Sadhna Phanse, Julian H. Kwan, Michael D. Blower, Kristine M. Abo
Publikováno v:
Molecular Cell
Human transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causative pathogen of the COVID-19 pandemic, exerts a massive health and socioeconomic crisis. The virus infects alveolar epithelial type 2 cells (AT2s), leading to l
Autor:
Amy B. Emerman, Michael D. Blower
Publikováno v:
Journal of Biological Chemistry. 293:12593-12605
RNA-binding proteins (RBP) are critical regulators of gene expression. Recent studies have uncovered hundreds of mRNA-binding proteins that do not contain annotated RNA-binding domains and have well-established roles in other cellular processes. Inve
Publikováno v:
RNA
Changes in gene expression are required to orchestrate changes in cell state during development. Most cells change patterns of gene expression through transcriptional regulation. In contrast, oocytes are transcriptionally silent and use changes in mR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9e550b7a23647ed72305dd8060a01fb
Publikováno v:
Mol Cell
PMC
PMC
SummaryEntering mitosis, the genome is restructured to facilitate chromosome segregation, accompanied by dramatic changes in gene expression. However, the mechanisms that underlie mitotic transcriptional regulation are unclear. In contrast to transcr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a884aa41d6cb3b792a2da1c05ae5923