Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Michael D Nodine"'
Autor:
Laura Arribas-Hernández, Sarah Rennie, Michael Schon, Carlotta Porcelli, Balaji Enugutti, Robin Andersson, Michael D Nodine, Peter Brodersen
Publikováno v:
eLife, Vol 10 (2021)
Gene regulation via N6-methyladenosine (m6A) in mRNA involves RNA-binding proteins that recognize m6A via a YT521-B homology (YTH) domain. The plant YTH domain proteins ECT2 and ECT3 act genetically redundantly in stimulating cell proliferation durin
Externí odkaz:
https://doaj.org/article/b9847e04c0e8441cae1b125dcde7e00e
Autor:
Ranjith K Papareddy, Katalin Páldi, Anna D Smolka, Patrick Hüther, Claude Becker, Michael D Nodine
Publikováno v:
eLife, Vol 10 (2021)
DNA methylation has evolved to silence mutagenic transposable elements (TEs) while typically avoiding the targeting of endogenous genes. Mechanisms that prevent DNA methyltransferases from ectopically methylating genes are expected to be of prime imp
Externí odkaz:
https://doaj.org/article/b6051461ff4049db9630c7e6f1170703
Autor:
Michael Borg, Ranjith K Papareddy, Rodolphe Dombey, Elin Axelsson, Michael D Nodine, David Twell, Frédéric Berger
Publikováno v:
eLife, Vol 10 (2021)
Alternation between morphologically distinct haploid and diploid life forms is a defining feature of most plant and algal life cycles, yet the underlying molecular mechanisms that govern these transitions remain unclear. Here, we explore the dynamic
Externí odkaz:
https://doaj.org/article/5d1ebfad4f2144ecbf2e2dcaf2575888
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-21 (2022)
Abstract We developed Bookend, a package for transcript assembly that incorporates data from different RNA-seq techniques, with a focus on identifying and utilizing RNA 5′ and 3′ ends. We demonstrate that correct identification of transcript star
Externí odkaz:
https://doaj.org/article/f8ce5169a3d8401b88a9fcba1ff28e08
Autor:
Ranjith K. Papareddy, Katalin Páldi, Subramanian Paulraj, Ping Kao, Stefan Lutzmayer, Michael D. Nodine
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-24 (2020)
Abstract Background Eukaryotic genomes are partitioned into euchromatic and heterochromatic domains to regulate gene expression and other fundamental cellular processes. However, chromatin is dynamic during growth and development and must be properly
Externí odkaz:
https://doaj.org/article/8ab754b2f58a4c5a97b7f54b59b8fb1c
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-6 (2017)
Abstract Normalization of high-throughput small RNA sequencing (sRNA-Seq) data is required to compare sRNA levels across different samples. Commonly used relative normalization approaches can cause erroneous conclusions due to fluctuating small RNA p
Externí odkaz:
https://doaj.org/article/17fc805a814547d18b623e1269983cae
Publikováno v:
Frontiers in Plant Science, Vol 8 (2017)
MicroRNAs are non-coding small RNA molecules that are involved in the post-transcriptional regulation of the genes that control various developmental processes in plants, including zygotic embryogenesis (ZE). miRNAs are also believed to regulate soma
Externí odkaz:
https://doaj.org/article/d47fadd6dbf64bd0abc14e988de5fda1
Publikováno v:
Genome Biology. 23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03335e9a45db906967ad41956bb81df0
https://doi.org/10.1186/s13059-022-02725-8
https://doi.org/10.1186/s13059-022-02725-8
Autor:
Julius Durr, Robert Maple, Stefano Amantia, Anne W. Sylvester, Ranjith K Papareddy, Saleh Tamim, Jacques Rouster, José F. Gutierrez-Marcos, Alexander Dawson, Blake C. Meyers, Anding Luo, Yang-Seok Lee, James A. Birchler, Charo I. Del Genio, Jonathan C. Lamb, Michael D. Nodine
Publikováno v:
Nature Plants. 7:34-41
Although plants are able to withstand a range of environmental conditions, spikes in ambient temperature can impact plant fertility causing reductions in seed yield and notable economic losses1,2. Therefore, understanding the precise molecular mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::180e8de0d12a3cb7e1527e2afc876cf0
https://doi.org/10.1038/s41477-020-00818-5
https://doi.org/10.1038/s41477-020-00818-5
Accurate annotation of transcript isoforms is crucial to understand gene functions, but automated methods for reconstructing full-length transcripts from RNA sequencing (RNA-seq) data remain imprecise. We developed Bookend, a software package for tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32b0267c7893c12a754194b6bec6f1cd
https://doi.org/10.1101/2022.01.12.476004
https://doi.org/10.1101/2022.01.12.476004
