Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Michael D Mauk"'
Publikováno v:
eLife, Vol 11 (2022)
The function of a feedback inhibitory circuit between cerebellar Purkinje cells and molecular layer interneurons (MLIs) was defined by combining optogenetics, neuronal activity recordings both in cerebellar slices and in vivo, and computational model
Externí odkaz:
https://doaj.org/article/2ee1043fd88842ee994a5a61150891de
Publikováno v:
IEEE Transactions on Neural Networks and Learning Systems. 28:510-522
This paper describes the learning and control capabilities of a biologically constrained bottom-up model of the mammalian cerebellum. Results are presented from six tasks: 1) eyelid conditioning; 2) pendulum balancing; 3) proportional-integral-deriva
Publikováno v:
Behavioral Neuroscience. 130:553-562
Averaging artifacts inherent in group acquisition curves can mask behavioral phenomena that are potentially revealing in terms of underlying neural mechanisms. To address this, we implemented a behavioral analysis of 106 rabbits trained over 4 sessio
Transforming a brief sensory event into a persistent neural response represents a mechanism for linking temporally disparate stimuli together to support learning. The cerebellum requires this type of persistent input during trace conditioning to enga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a46c6eae298e9aa4904fe65f3b99a08f
https://europepmc.org/articles/PMC6181306/
https://europepmc.org/articles/PMC6181306/
Autor:
Horatiu Voicu, Michael D. Mauk
Publikováno v:
Neurobiology of learning and memory. 170
To support computation the activity of neurons must vary within a useful range, which highlights one potential value of homeostatic plasticity. The interconnectedness of the brain, however, introduces the possibility that combinations of homeostatic
Publikováno v:
eLife, Vol 7 (2018)
eLife
eLife
Most movements are not unitary, but are comprised of sequences. Although patients with cerebellar pathology display severe deficits in the execution and learning of sequences (Doyon et al., 1997; Shin and Ivry, 2003), most of our understanding of cer
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 38(33)
Results from previous lesion studies have been interpreted as evidence that the cerebellar cortex plays different roles for delay and trace conditioning of eyelid responses. However, the cerebellar cortex is organized by parasagittal stripes of Purki