Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Michael D, Powell"'
Autor:
Susan M. Watanabe, David A. Nyenhuis, Mahfuz Khan, Lorna S. Ehrlich, Irene Ischenko, Michael D. Powell, Nico Tjandra, Carol A. Carter
Publikováno v:
Viruses, Vol 16, Iss 10, p 1566 (2024)
Tsg101, a component of the endosomal sorting complex required for transport (ESCRT), is responsible for recognition of events requiring the machinery, as signaled by cargo tagging with ubiquitin (Ub), and for recruitment of downstream acting subunits
Externí odkaz:
https://doaj.org/article/ef7af3353cf84ebe87004a4b3dd69d12
Autor:
Kenya DeBarros, Mahfuz Khan, Morgan Coleman, Vincent C. Bond, Virginia Floyd, Erick Gbodossou, Amad Diop, Lauren R. H. Krumpe, Barry R. O’Keefe, Michael D. Powell
Publikováno v:
Viruses, Vol 16, Iss 9, p 1433 (2024)
MoMo30 is an antiviral protein isolated from aqueous extracts of Momordica balsamina L. (Senegalese bitter melon). Previously, we demonstrated MoMo30’s antiviral activity against HIV-1. Here, we explore whether MoMo30 has antiviral activity against
Externí odkaz:
https://doaj.org/article/6a84d8389db9421eb40115bf1581ae06
Autor:
James R. Rose, Bagdeser Akdogan-Ozdilek, Andrew R. Rahmberg, Michael D. Powell, Sakeenah L. Hicks, Christopher D. Scharer, Jeremy M. Boss
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-19 (2023)
An integrated analysis uncovers transcriptional and epigenetic differences of human circulating memory T cell subsets and identifies unique transcription factor networks associated with memory subset differentiation.
Externí odkaz:
https://doaj.org/article/a067bd43035a480cbc06a1f70910044e
Autor:
Mahfuz Khan, Amad Diop, Erick Gbodossou, Peng Xiao, Morgan Coleman, Kenya De Barros, Hao Duong, Vincent C. Bond, Virginia Floyd, Kofi Kondwani, Valerie Montgomery Rice, Sandra Harris-Hooker, Francois Villinger, Michael D. Powell
Publikováno v:
Virology Journal, Vol 20, Iss 1, Pp 1-15 (2023)
Abstract Background Plants are used in traditional healing practices of many cultures worldwide. Momordica balsamina is a plant commonly used by traditional African healers as a part of a treatment for HIV/AIDS. It is typically given as a tea to pati
Externí odkaz:
https://doaj.org/article/a46bff83c98a4e41a8f5930234e3661f
Autor:
Kaitlin A. Read, Devin M. Jones, Srijana Pokhrel, Emily D. S. Hales, Aditi Varkey, Jasmine A. Tuazon, Caprice D. Eisele, Omar Abdouni, Abbey Saadey, Melissa R. Leonard, Robert T. Warren, Michael D. Powell, Jeremy M. Boss, Emily A. Hemann, Jacob S. Yount, Gang Xin, Hazem E. Ghoneim, Chan-Wang J. Lio, Aharon G. Freud, Patrick L. Collins, Kenneth J. Oestreich
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
The regulation and direction of CD4+ T cells into phenotypic and functional lineages is coordinated by a complex set of mechanisms. Here the authors show a role for Aiolos as a regulator of the CD4+ cytotoxic and T follicular helper lineages.
Externí odkaz:
https://doaj.org/article/db3616878fde4edbb2df4e62fd0817bd
Autor:
Manuja Gunasena, Rajni Kant Shukla, Naiquan Yao, Oscar Rosas Mejia, Michael D. Powell, Kenneth J. Oestreich, Michel de Jesús Aceves-Sánchez, Mario Alberto Flores-Valdez, Namal P. M. Liyanage, Richard T. Robinson
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract The vaccine Mycobacterium bovis Bacillus Calmette-Guérin (BCG) elicits an immune response that is protective against certain forms of tuberculosis (TB); however, because BCG efficacy is limited it is important to identify alternative TB vac
Externí odkaz:
https://doaj.org/article/39d7006d20634ee79c2e206a6e612978
Autor:
Michael D. Powell, Peiyuan Lu, Dennis K. Neeld, Anna K. Kania, Lou-Ella M. M. George-Alexander, Alexander P. R. Bally, Christopher D. Scharer, Jeremy M. Boss
Publikováno v:
ImmunoHorizons. 6:872-882
CD8 cytotoxic T cells are a potent line of defense against invading pathogens. To aid in curtailing aberrant immune responses, the activation status of CD8 T cells is highly regulated. One mechanism in which CD8 T cell responses are dampened is via s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c33cf5c8172df583c388c40cdfeda14a
https://doi.org/10.4049/immunohorizons.2100112
https://doi.org/10.4049/immunohorizons.2100112
Autor:
Madeleine Strickland, Lorna S. Ehrlich, Susan Watanabe, Mahfuz Khan, Marie-Paule Strub, Chi-Hao Luan, Michael D. Powell, Jonathan Leis, Nico Tjandra, Carol A. Carter
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Tsg101 is a component of the host cellular ESCRT machinery and is required for HIV-1 replication. Here, the authors show that disruption of ubiquitin binding of the Tsg101 UEV domain through commonly used drugs arrests virus assembly, which might fac
Externí odkaz:
https://doaj.org/article/2ecc918c7b1b4a77b36ae1b966756894
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
CD4+ T helper cells are capable of differentiating into a number of effector subsets that perform diverse functions during adaptive immune responses. The differentiation of each of these subsets is governed, in large part, by environmental cytokine s
Externí odkaz:
https://doaj.org/article/95774922fdfa4c9a82d8cb79f9272e50
Autor:
Paul W. McDonald, Kaitlin A. Read, Chandra E. Baker, Ashlyn E. Anderson, Michael D. Powell, André Ballesteros-Tato, Kenneth J. Oestreich
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
It remains incompletely understood how cytokines shape TH1 cell differentiation to central memory T (TCM) and follicular T helper (TFH) cells. Here the authors show that TH1 cells can co-initiate the expression of both TFH and TCM gene programs and t
Externí odkaz:
https://doaj.org/article/ed8ba91356794cf9a2f6d0b4dfd365cb