Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Michael D, Dore"'
Autor:
Michael D. Dore, Muhammad Ghufran Rafique, Tianxiao Peter Yang, Marlo Zorman, Casey M. Platnich, Pengfei Xu, Tuan Trinh, Felix J. Rizzuto, Gonzalo Cosa, Jianing Li, Alba Guarné, Hanadi F. Sleiman
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Biopolymers such as nucleic acids and proteins exhibit dynamic backbone folding, wherein site-specific intramolecular interactions determine overall structure. Proteins then hierarchically assemble into supramolecular polymers such as microt
Externí odkaz:
https://doaj.org/article/51568a0edb0a4963a9a4a14772d6fb24
Publikováno v:
Journal of the American Chemical Society. 144:12272-12279
The self-assembly of block copolymers is often rationalized by structure and microphase separation; pathways that diverge from this parameter space may provide new mechanisms of polymer self-assembly. Here, we show that the sequence and length of sin
Autor:
Jacob M. Remington, Violeta Toader, Hanadi F. Sleiman, Jianing Li, Xin Luo, Michael D. Dore, Tuan Trinh, Marlo L. Zorman, Donatien de Rochambeau, Pengfei Xu, Casey M. Platnich, Gonzalo Cosa
Publikováno v:
Chem. 7:2395-2414
Summary DNA nanostructures are highly addressable and compatible with biological systems but often require hundreds of unique strands for their assembly. On the other hand, nature can assemble complex structures from identical building blocks by comp
Autor:
Felix J, Rizzuto, Casey M, Platnich, Xin, Luo, Yao, Shen, Michael D, Dore, Christophe, Lachance-Brais, Alba, Guarné, Gonzalo, Cosa, Hanadi F, Sleiman
Publikováno v:
Nature chemistry. 13(9)
Biochemical networks interconnect, grow and evolve to express new properties as different chemical pathways are selected during a continuous cycle of energy consumption and transformation. In contrast, synthetic systems that push away from equilibriu
Publikováno v:
Chemical Communications. 54:11296-11299
RNA has inherent therapeutic and structural properties that make it an important component of biologically-functional nanoparticles. Using DNA-amphiphiles as synthetic templates, we report the synthesis of two classes of RNA-amphiphiles that self-ass
Autor:
Michael D, Dore, Hanadi F, Sleiman
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2063
DNA nanotechnology has been used to create DNA containing nanostructures with well-defined sizes and shapes-properties highly applicable to drug delivery. By appending sequence-defined hydrophobic segments to DNA, DNA amphiphiles are created whose st
Autor:
Michael D. Dore, Hanadi F. Sleiman
Publikováno v:
Methods in Molecular Biology ISBN: 9781071601372
DNA nanotechnology has been used to create DNA containing nanostructures with well-defined sizes and shapes-properties highly applicable to drug delivery. By appending sequence-defined hydrophobic segments to DNA, DNA amphiphiles are created whose st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c1e84a4dbd3e755f20e85758e08dd94
https://doi.org/10.1007/978-1-0716-0138-9_8
https://doi.org/10.1007/978-1-0716-0138-9_8
Publikováno v:
Journal of the American Chemical Society. 139(21)
The development of nucleic acid therapeutics has been hampered by issues associated with their stability and in vivo delivery. To address these challenges, we describe a new strategy to engineer DNA structures with strong binding affinity to human se