Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Michael D, Blower"'
Publikováno v:
Molecular Biology of the Cell. 34
The authors investigate inheritance of nuclear RNA by G1 cells following mitosis. They find that multiple pathways regulate differential inheritance of nuclear RNAs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbbcf41c651bb7dabc12ef7b194fc53f
https://doi.org/10.1091/mbc.e23-01-0004
https://doi.org/10.1091/mbc.e23-01-0004
Autor:
Michael D. Blower
Publikováno v:
Cell Reports, Vol 15, Iss 8, Pp 1624-1633 (2016)
Centromeric transcription is widely conserved; however, it is not clear what role centromere transcription plays during mitosis. Here, I find that centromeres are transcribed in Xenopus egg extracts into a long noncoding RNA (lncRNA; cen-RNA) that lo
Externí odkaz:
https://doaj.org/article/12a224e70f69453c8bc4ef8e103ba3a1
Mitosis results in a dramatic reorganization of chromatin structure in order to promote chromatin compaction and segregation to daughter cells. Consequently, mitotic entry is accompanied by transcriptional silencing and removal of most chromatin-boun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aef8d12ebb988ab7c5b3acb68b08187d
https://doi.org/10.1101/2022.10.06.511141
https://doi.org/10.1101/2022.10.06.511141
Autor:
Saravanapriah Nadarajan, Talley J Lambert, Elisabeth Altendorfer, Jinmin Gao, Michael D Blower, Jennifer C Waters, Monica P Colaiácovo
Publikováno v:
eLife, Vol 6 (2017)
The synaptonemal complex (SC) is an ultrastructurally conserved proteinaceous structure that holds homologous chromosomes together and is required for the stabilization of pairing interactions and the completion of crossover (CO) formation between ho
Externí odkaz:
https://doaj.org/article/a687ce32370b43c2aa5ffeafbfcc3c61
Autor:
Saravanapriah Nadarajan, Firaz Mohideen, Yonatan B Tzur, Nuria Ferrandiz, Oliver Crawley, Alex Montoya, Peter Faull, Ambrosius P Snijders, Pedro R Cutillas, Ashwini Jambhekar, Michael D Blower, Enrique Martinez-Perez, J Wade Harper, Monica P Colaiacovo
Publikováno v:
eLife, Vol 5 (2016)
Asymmetric disassembly of the synaptonemal complex (SC) is crucial for proper meiotic chromosome segregation. However, the signaling mechanisms that directly regulate this process are poorly understood. Here we show that the mammalian Rho GEF homolog
Externí odkaz:
https://doaj.org/article/4df71421871c44c4a4879464b70529bc
Autor:
Filip A. Konopacki, Hovy Ho-Wai Wong, Asha Dwivedy, Anaïs Bellon, Michael D. Blower, Christine E. Holt
Publikováno v:
Open Biology, Vol 6, Iss 4 (2016)
Endocytosis and local protein synthesis (LPS) act coordinately to mediate the chemotropic responses of axons, but the link between these two processes is poorly understood. The endosomal sorting complex required for transport (ESCRT) is a key regulat
Externí odkaz:
https://doaj.org/article/b840736eec2a474caf211487ad2bb95c
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100748 (2014)
Accurate chromosome segregation is essential for cell viability. The mitotic spindle is crucial for chromosome segregation, but much remains unknown about factors that regulate spindle assembly. Recent work implicates RNA in promoting proper spindle
Externí odkaz:
https://doaj.org/article/e9de5420f44d44dc889bee59844a769a
Publikováno v:
Trends Cell Biol
Beyond its originally discovered role tethering replicated sister chromatids, cohesin has emerged as a master regulator of gene expression. Recent advances in chromatin topology resolution and single-cell studies have revealed that cohesin has a pivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f2768137c52f27d7d4f879333333f62
https://europepmc.org/articles/PMC8364472/
https://europepmc.org/articles/PMC8364472/
Autor:
Carlos Villacorta-Martin, Shaghayegh Farhangmehr, Ryan M. Hekman, Mohsan Saeed, Carlos Perea-Resa, Robert A. Davey, Andrew Emili, Jian Zhao, Peter E.A. Ash, Raghuveera Kumar Goel, Benjamin C. Blum, Andrew A. Wilson, Benjamin J. Blencowe, Ulrich Braunschweig, Benjamin Wolozin, Andrew Tilston-Lunel, Darrell N. Kotton, Ji-Xin Cheng, Avik Basu, Alexandra Mora-Martin, Esther Bullitt, Rhiannon B. Werder, Mark E. McComb, Dmitry A. Kretov, Dzmitry Padhorny, Sandeep Ojha, Shawn M. Lyons, Konstantinos D. Alysandratos, Jessie Huang, Anne Hinds, Valentina Perissi, J. J. Patten, Ahmed Youssef, Xaralabos Varelas, John H Connor, Dima Kozakov, Mamta Verma, Dante Bolzan, Indranil Paul, Ellen L Suder, Eric J. Burks, Matthew D. Layne, Elke Mühlberger, Stefan Wuchty, Adam J. Hume, Daniel Cifuentes, Sadhna Phanse, Julian H. Kwan, Michael D. Blower, Kristine M. Abo
Publikováno v:
Molecular Cell
Human transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causative pathogen of the COVID-19 pandemic, exerts a massive health and socioeconomic crisis. The virus infects alveolar epithelial type 2 cells (AT2s), leading to l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::469deb34c0395f965c7f17d2e99c8022