Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Michael Cypress"'
Publikováno v:
Physiology. 38
Introduction: Mechanical stress (e.g., pressure overload), cytokines, growth factors, and neurohumoral mediators stimulate cardiac fibroblast (CF) activation, which promotes extracellular matrix (ECM) protein synthesis leading to cardiac fibrosis and
Autor:
Isabel Chaput, Madeline Kelly, Maria Landherr, Iuliia Polina, Bridget Nieto, Michael Cypress, Bong Sook Jhun, Peng Zhang, Jin O-Uchi
Publikováno v:
Physiology. 38
Introduction: A mitochondrial fusion protein, Mitofusin 2 (Mfn2) serves as one of the major components for tethering the mitochondria and endoplasmic reticulum (ER), which regulates the exchange of lipids, Ca2+, and reactive oxygen species (ROS) acro
Publikováno v:
Physiology. 38
Introduction: Discovery of the molecular identity of the mitochondrial Ca2+ (mtCa2+) uniporter complex (mtCUC) provides rapid progress in characterizing mtCa2+ handling and its roles in regulating cellular functions. MCU, a pore-forming subunit of mt