Výsledky vyhledávání - "Michael Cecerle"

Akademický článek

Efficacy and Safety of LetibotulinumtoxinA in the Treatment of Moderate and Severe Glabellar Lines in Females 35 to 50 Years of Age: Post Hoc Analyses of the Phase 3 Clinical Study Data

Autor: Michael Gold, Susan Taylor, Daniel S Mueller, Jeffrey Adelglass, Joely Kaufman-Janette, Sue E Cox, Michael Cecerle, Konstantin Frank, Mark Nestor

Publikováno v: Aesthetic Surgery Journal Open Forum, Vol 6 (2024)

Abstract BackgroundBotulinum toxin type A (BoNT-A) injections continue to be widely used as a common treatment for both males and females. According to a recent survey conducted by the International Society of Plastic Aesthetic Surgeons, the majorit

Externí odkaz: https://doaj.org/article/f11ff6c17b274877a6fa44a0521a1f84

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Biological Explanation of Clinically Observed Elevation of TFPI Plasma Levels After Treatment with TFPI-Antagonistic Aptamer BAX 499

Autor: Benny Sorensen, Michael Cecerle, Michael Dockal, Wing Yen Wong, Hartmut J. Ehrlich, Bruce M. Ewenstein, Robert Pachlinger, Friedrich Scheiflinger, Maureen Conlan, Rudolf Hartmann, Sabine Knappe

Publikováno v: Blood. 120:1104-1104

Abstract 1104 BAX 499, an aptamer that binds with a high affinity to TFPI (KD ∼0.1 nM), blocks the anticoagulant action of TFPI in plasma and model systems. BAX 499 was recently tested in a phase 1 safety, tolerability and ex vivo efficacy study in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::60a69ab883c8e0adcae47be5403f9d20
https://doi.org/10.1182/blood.v120.21.1104.1104

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