Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Michael C. Wei"'
Autor:
Matthew J. Maurer, Carla Casulo, Melissa C. Larson, Thomas M. Habermann, Izidore S. Lossos, Yucai Wang, Loretta J. Nastoupil, Christopher Strouse, Dai Chihara, Peter Martin, Jonathon B. Cohen, Brad S. Kahl, W Richard Burack, Jean L. Koff, Yong Mun, Anthony Masaquel, Mei Wu, Michael C. Wei, Ashwini Shewade, Jia Li, James R. Cerhan, Brian K. Link, Christopher R. Flowers
Publikováno v:
Haematologica, Vol 999, Iss 1 (2023)
Mosunetuzumab is a novel bispecific antibody targeting epitopes on CD3 on T cells and CD20 on B cells with the goal of inducing T-cell mediated elimination of malignant B cells. A recent pivotal phase I/II clinical trial (GO29781) demonstrated that m
Externí odkaz:
https://doaj.org/article/1d7e46afb331468e9c6f00cad9ff0929
Autor:
Monica E. Susilo, Chi‐Chung Li, Kapil Gadkar, Genevive Hernandez, Ling‐Yuh Huw, Jin Y. Jin, Shen Yin, Michael C. Wei, Saroja Ramanujan, Iraj Hosseini
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 7, Pp 1134-1148 (2023)
Abstract Phase I oncology clinical trials often comprise a limited number of patients representing different disease subtypes who are divided into cohorts receiving treatment(s) at different dosing levels and schedules. Here, we leverage a previously
Externí odkaz:
https://doaj.org/article/2bc7d8bf72c444f492e191b7c0cbf612
Autor:
Chiou-Hong Lin, Stephen Hon-Kit Wong, Jason H. Kurzer, Corina Schneidawind, Michael C. Wei, Jesús Duque-Afonso, Johan Jeong, Xuhui Feng, Michael L. Cleary
Publikováno v:
Cell Reports, Vol 23, Iss 4, Pp 1166-1177 (2018)
Summary: Acute lymphoblastic leukemia (ALL) is associated with significant morbidity and mortality, necessitating further improvements in diagnosis and therapy. Targeted therapies directed against chromatin regulators are emerging as promising approa
Externí odkaz:
https://doaj.org/article/9ec9435c885040218a99c249ac02f40c
Autor:
Nancy L. Bartlett, Laurie H. Sehn, Matthew J. Matasar, Stephen J. Schuster, Sarit Assouline, Pratyush Giri, John Kuruvilla, Miguel Canales, Sascha Dietrich, Keith Fay, Matthew Ku, Loretta J. Nastoupil, Michael C. Wei, Shen Yin, Iris To, Huang Huang, Juliana Min, Elicia Penuel, L. Elizabeth Budde
Publikováno v:
Blood. 140:1467-1470
Autor:
Elizabeth L. Budde, Nancy L. Bartlett, Pratyush Giri, Stephen J. Schuster, Sarit Assouline, Sung-Soo Yoon, Keith Fay, Matthew J. Matasar, Norma C. Gutierrez, Paula Marlton, Martin Dreyling, Dok Hyun Yoon, Georg Hess, John Radford, Volker Wiebking, Shen Yin, Eva Cybulski, David C. Turner, Huang Huang, Mingzhu Zhou, Elicia Penuel, Michael C. Wei, Laurie H. Sehn
Publikováno v:
Blood. 140:3753-3755
Autor:
Sarah F. McGough, Natasha Shamas, Jue Wang, Mahmoud Jaber, Binay Swarup, Marie-Helene Blanchet Zumofen, Bertrand Lautié, Joana Parreira, Michael C. Wei, Ashwini Shewade
Publikováno v:
Blood. 140:3658-3660
Autor:
Adam J. Olszewski, L. Elizabeth Budde, Julio Chavez, Nilanjan Ghosh, Manali Kamdar, Izidore S. Lossos, Catherine Diefenbach, Waleed Sabry, Kathleen Dorritie, Ling-Yuh Huw, Song Pham, Ting Jia, Hao Wu, Iris To, Michael C. Wei, Sarit Assouline
Publikováno v:
Blood. 140:3757-3759
Autor:
Nancy L. Bartlett, Sarit Assouline, Pratyush Giri, Stephen J. Schuster, Chan Yoon Y Cheah, Matthew J Matasar, Gareth P. Gregory, Dok-Hyun Yoon, Mazyar Shadman, Keith Fay, Sung-Soo Yoon, Carlos Panizo, Ian W. Flinn, Anna Johnston, Francesc Bosch, Laurie H Sehn, Michael C. Wei, Shen Yin, Iris To, Chi-Chung Li, Huang Huang, Antonia Kwan, Elicia Penuel, elizabeth Elizabeth budde
Publikováno v:
Blood Advances.
As part of a phase 1/2 study, this single-arm expansion cohort established the efficacy and safety of mosunetuzumab monotherapy in patients with relapsed/refractory (R/R) diffuse large B-cell lymphoma (DLBCL) (received >=2 prior lines of therapy). In
Data from E2A-PBX1 Remodels Oncogenic Signaling Networks in B-cell Precursor Acute Lymphoid Leukemia
Autor:
Michael L. Cleary, Michael C. Bassik, Stephen Hon-Kit Wong, Corina Schneidawind, Jason H. Kurzer, Jue Feng, Michael C. Wei, Kyuho Han, Chiou-Hong Lin, Jesús Duque-Afonso
There is limited understanding of how signaling pathways are altered by oncogenic fusion transcription factors that drive leukemogenesis. To address this, we interrogated activated signaling pathways in a comparative analysis of mouse and human leuke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8aa2306bbeb855d310e6f2c8620a9efa
https://doi.org/10.1158/0008-5472.c.6508719.v1
https://doi.org/10.1158/0008-5472.c.6508719.v1
Autor:
David M. Hyman, Michael C. Wei, Timothy R. Wilson, Maurizio Scaltriti, Heidi M. Savage, Surai Jones, John Bond, Helen Won, Lara Dunn, Jasgit C. Sachdev, Philippe L. Bedard, Raid Aljumaily, Cynthia X. Ma, Vincent Ribrag, Manish R. Patel, Anton Melnyk, Valentina Gambardella, Cristina Saura, Dejan Juric, Matthew T. Chang, Komal Jhaveri
Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64b61946403042657dff6a32ae72420c
https://doi.org/10.1158/1078-0432.22479515.v1
https://doi.org/10.1158/1078-0432.22479515.v1