Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Michael C. Washburn"'
Autor:
Michael C. Washburn, Boyko Kakaradov, Balaji Sundararaman, Emily Wheeler, Shawn Hoon, Gene W. Yeo, Heather A. Hundley
Publikováno v:
Cell Reports, Vol 6, Iss 4, Pp 599-607 (2014)
Inadequate adenosine-to-inosine editing of noncoding regions occurs in disease but is often uncorrelated with ADAR levels, underscoring the need to study deaminase-independent control of editing. C. elegans have two ADAR proteins, ADR-2 and the theor
Externí odkaz:
https://doaj.org/article/41e2f6164f6b4788a9c7ae674b177067
Autor:
Sarah N Deffit, Brian A Yee, Aidan C Manning, Suba Rajendren, Pranathi Vadlamani, Emily C Wheeler, Alain Domissy, Michael C Washburn, Gene W Yeo, Heather A Hundley
Publikováno v:
eLife, Vol 6 (2017)
ADAR proteins alter gene expression both by catalyzing adenosine (A) to inosine (I) RNA editing and binding to regulatory elements in target RNAs. Loss of ADARs affects neuronal function in all animals studied to date. Caenorhabditis elegans lacking
Externí odkaz:
https://doaj.org/article/0be709163d094d89ae3e71f8c13c24d9
Publikováno v:
The Journal of Molecular Diagnostics : JMD
Genetically isolated populations, such as the Old Order Amish and Old Order Mennonite communities, have an increased incidence of specific autosomal recessive disorders caused by the founder effect. In these populations, robust expanded carrier scree
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d54e66078d96b4b48129d2b88a856319
https://pubmed.ncbi.nlm.nih.gov/31028937
https://pubmed.ncbi.nlm.nih.gov/31028937
Autor:
Nabeel S. Ganem, Aidan C. Manning, Einav Mantsur, Emily C. Wheeler, Ayelet T. Lamm, Noa Ben-Asher, Orna Ben-Naim Zgayer, Heather A. Hundley, Michael C. Washburn, Sarah N. Deffit, Gene W. Yeo
Publikováno v:
Cell reports
SUMMARY A-to-I RNA editing, catalyzed by ADAR proteins, is widespread in eukaryotic transcriptomes. Studies showed that, in C. elegans, ADR-2 can actively deaminate dsRNA, whereas ADR-1 cannot. Therefore, we set out to study the effect of each of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35e3a39934921ef5e5b737b98b17689d
https://pubmed.ncbi.nlm.nih.gov/31018137
https://pubmed.ncbi.nlm.nih.gov/31018137
Autor:
Michael C. Washburn, Emily C. Wheeler, Sarah N. Deffit, Suba Rajendren, Brian A. Yee, Alain Domissy, Gene W. Yeo, Pranathi Vadlamani, Aidan C. Manning, Heather A. Hundley
Publikováno v:
eLife, Vol 6 (2017)
DNA is the blueprint that tells each cell in an organism how it should operate. It encodes the instructions to make proteins and other molecules. To make a protein, a section of DNA known as a gene is used as a template to make molecules known as mes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8155bb622cdae2af9dbfa65c0a542346
https://doi.org/10.7554/elife.28625
https://doi.org/10.7554/elife.28625
Autor:
Sarah N Deffit, Brian A Yee, Aidan C Manning, Suba Rajendren, Pranathi Vadlamani, Emily C Wheeler, Alain Domissy, Michael C Washburn, Gene W Yeo, Heather A Hundley
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9cc14afe1d133666045c8a2301d3d4b8
https://doi.org/10.7554/elife.28625.018
https://doi.org/10.7554/elife.28625.018
Autor:
Sarah N, Deffit, Brian A, Yee, Aidan C, Manning, Suba, Rajendren, Pranathi, Vadlamani, Emily C, Wheeler, Alain, Domissy, Michael C, Washburn, Gene W, Yeo, Heather A, Hundley
Publikováno v:
eLife
ADAR proteins alter gene expression both by catalyzing adenosine (A) to inosine (I) RNA editing and binding to regulatory elements in target RNAs. Loss of ADARs affects neuronal function in all animals studied to date. Caenorhabditis elegans lacking
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a82fcfa90aabd4f7c53d362ee0e66683
https://pubmed.ncbi.nlm.nih.gov/28925356
https://pubmed.ncbi.nlm.nih.gov/28925356
Autor:
Boyko Kakaradov, Heather A. Hundley, Balaji Sundararaman, Gene W. Yeo, Shawn Hoon, Michael C. Washburn, Emily C. Wheeler
Publikováno v:
Cell Reports, Vol 6, Iss 4, Pp 599-607 (2014)
Inadequate adenosine-to-inosine editing of noncoding regions occurs in disease but is often uncorrelated with ADAR levels, underscoring the need to study deaminase-independent control of editing. C. elegans have two ADAR proteins, ADR-2 and the theor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b80537b5a8ee4e572c89e42eb3c49593
https://doi.org/10.1016/j.celrep.2014.01.011
https://doi.org/10.1016/j.celrep.2014.01.011
Publikováno v:
Advances in experimental medicine and biology. 907
RNA editing is a cellular process used to expand and diversify the RNA transcripts produced from a generally immutable genome. In animals, the most prevalent type of RNA editing is adenosine (A) to inosine (I) deamination catalyzed by the ADAR family
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7557fbc3eda7a24dc72c5efbb1efba57
https://pubmed.ncbi.nlm.nih.gov/27256387
https://pubmed.ncbi.nlm.nih.gov/27256387
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783319290713
RNA editing is a cellular process used to expand and diversify the RNA transcripts produced from a generally immutable genome. In animals, the most prevalent type of RNA editing is adenosine (A) to inosine (I) deamination catalyzed by the ADAR family
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b57e73c7f59e3f34044e2aad9af6d93
https://doi.org/10.1007/978-3-319-29073-7_8
https://doi.org/10.1007/978-3-319-29073-7_8