Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Michael C. Pitman"'
Autor:
Blake Mertz, Steven D. E. Fried, Michael F. Brown, Michael C. Pitman, Udeep Chawla, Nipuna Weerasinghe, Andrey V. Struts, Suchithranga M. D. C. Perera, Anna R. Eitel
Publikováno v:
Angewandte Chemie International Edition. 60:2288-2295
Visual rhodopsin is an important archetype for G-protein-coupled receptors, which are membrane proteins implicated in cellular signal transduction. Herein, we show experimentally that approximately 80 water molecules flood rhodopsin upon light absorp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a263b928e55bb7fd63e2a336f8c627a4
https://doi.org/10.1002/anie.202003342
https://doi.org/10.1002/anie.202003342
Autor:
Suchithranga M. D. C. Perera, Anna R. Eitel, Steven D. E. Fried, Nipuna Weerasinghe, Michael F. Brown, Margaret R. Vos, Gabrielle I. Fitzwater, Carolanne E. Norris, Johnathan D. Somers, Michael C. Pitman, Andrey V. Struts
Publikováno v:
The FASEB Journal. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2cfc3f9198c009d1956802d04514e7ed
https://doi.org/10.1096/fasebj.2019.33.1_supplement.462.1
https://doi.org/10.1096/fasebj.2019.33.1_supplement.462.1
Autor:
Suchithranga M. D. C. Perera, Anna R. Eitel, Udeep Chawla, Andrey V. Struts, Michael C. Pitman, Gabrielle I. Fitzwater, Blake Mertz, Nipuna Weerasinghe, Steven D. E. Fried, Johnathan D. Somers, Michael F. Brown
Publikováno v:
Biophysical Journal. 118:527a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d3841e3d736d4b87bd2d137fb0a10db
https://doi.org/10.1016/j.bpj.2019.11.2895
https://doi.org/10.1016/j.bpj.2019.11.2895
Autor:
Patricia H. Reggio, Michael C. Pitman, Nicholas Leioatts, Jian Cai, Diane L. Lynch, Jagjeet S. Mnpotra, Alan Grossfield, Zhao-Hui Song, Dow P. Hurst, Zhuanhong Qiao
Publikováno v:
Journal of Biological Chemistry. 289:20259-20272
In this study, we applied a comprehensive G protein-coupled receptor-Gαi protein chemical cross-linking strategy to map the cannabinoid receptor subtype 2 (CB2)- Gαi interface and then used molecular dynamics simulations to explore the dynamics of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ddac2512ed94a5f080fa581c4f127e2
https://doi.org/10.1074/jbc.m113.539916
https://doi.org/10.1074/jbc.m113.539916
Autor:
Michael F. Brown, Alan Grossfield, Tod D. Romo, Karina Martinez-Mayorga, Scott E. Feller, Blake Mertz, Michael C. Pitman, Nicholas Leioatts
Publikováno v:
Biochemistry. 53:376-385
Rhodopsin, the mammalian dim-light receptor, is one of the best-characterized G-protein-coupled receptors, a pharmaceutically important class of membrane proteins that has garnered a great deal of attention because of the recent availability of struc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59d340697c585248449799d6f080e583
https://doi.org/10.1021/bi4013947
https://doi.org/10.1021/bi4013947
Autor:
Suchithranga M. D. C. Perera, Nipuna Weerasinghe, Steven D. E. Fried, Anna R. Eitel, Michael C. Pitman, Andrey V. Struts, Carolanne E. Norris, Gabrielle I. Fitzwater, Michael F. Brown, Johnathan D. Somers
Publikováno v:
Biophysical Journal. 116:207a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa60cd95dbb7fc6336fca0b47a701f1a
https://doi.org/10.1016/j.bpj.2018.11.1140
https://doi.org/10.1016/j.bpj.2018.11.1140
Autor:
Alexei Yeliseev, Klaus Gawrisch, Patricia H. Reggio, Diane L. Lynch, Alan Grossfield, Michael C. Pitman, Tomohiro Kimura, Dow P. Hurst, Krishna Vukoti
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 82:452-465
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc1a904baf8e57f9157b43bf34662828
https://doi.org/10.1002/prot.24411
https://doi.org/10.1002/prot.24411
Autor:
Annie Huang, Suchithranga M. D. C. Perera, Michael F. Brown, Thomas A. Knowles, Liangju Kaung, Rami Musharrafieh, Hongjun Liang, Michael C. Pitman, Jun Wang, Udeep Chawla, Wan Zheng
Publikováno v:
ResearcherID
Integral membrane proteins constitute more than 30% of the human genome. Substantial lipid-protein interactions contribute to the structure and function of membrane proteins such as GPCRs and viral membrane ion channels. We address how physical prope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6585d9700c96e0a85d327d28af71540
Autor:
Michael C. Pitman, Michael F. Brown, Scott E. Feller, Alexander Vogel, Alan Grossfield, Bjoern E.S. Olausson
Publikováno v:
Journal of the American Chemical Society. 134:4324-4331
We present a detailed analysis of the behavior of the highly flexible post- translational lipid modifications of rhodopsin from multiple-microsecond all-atom molecular dynamics simulations. Rhodopsin was studied in a realistic membrane environment th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53a3c34c0ae8484d925f8e52a36e4f2f
https://doi.org/10.1021/ja2108382
https://doi.org/10.1021/ja2108382
Autor:
Michael C. Pitman, Adri C. T. van Duin
Publikováno v:
Journal of the American Chemical Society. 134:3042-3053
The dynamics of water confined to mesoporous regions in minerals such as swelling clays and zeolites is fundamental to a wide range of resource management issues impacting many processes on a global scale, including radioactive waste containment, des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79638324330b1af6a5e532a3e0341d12
https://doi.org/10.1021/ja208894m
https://doi.org/10.1021/ja208894m