Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Michael C. Matelich"'
Autor:
Megumi Tsuchiya, James B. Wiesner, Masami Nakane, Atsushi Nagahisa, Michael C. Matelich, Matthew Allan, Robert H Lemus, Brett C. Bookser, Mark D. Erion, Bheemarao G. Ugarkar
Publikováno v:
Journal of Medicinal Chemistry. 48:7808-7820
4-(Phenylamino)-5-phenyl-7-(5-deoxy-beta-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine 1 and related compounds known as "diaryltubercidin" analogues are potent inhibitors of adenosine kinase (AK) and are orally active in animal models of pain such as the
Autor:
Barry M. Trost, Michael C. Matelich
Publikováno v:
ChemInform. 23
Autor:
Michael C. Matelich, Barry M. Trost
Publikováno v:
ChemInform. 23
A simple synthesis of (Z)-2-trimethylsilylmethyl-2-buten-1-ol from 2-butyn-1-ol provides ready access to disubstituted bifunctional conjunctive reagents such as the title compound. Palladium(0) catalysts initiate cycloaddition to electron-deficient o
Autor:
Yoshito Kishi, Denice M. Spero, Keith R. Buszek, Suk Kyoon Yoon, Craig J. Forsyth, Francis G. Fang, Sun Ho Jung, Michael C. Matelich, Paul Michael Scola, Thomas Daniel Aicher
Publikováno v:
ChemInform. 23
Autor:
Michael C. Matelich, Barry M. Trost
Publikováno v:
Synthesis. 1992:151-156
A simple synthesis of (Z)-2-trimethylsilylmethyl-2-buten-1-ol from 2-butyn-1-ol provides ready access to disubstituted bifunctional conjunctive reagents such as the title compound. Palladium(0) catalysts initiate cycloaddition to electron-deficient o
Autor:
Jay DaRe, Serge H. Boyer, Timothy J. Colby, Paul D. van Poelje, Mark D. Erion, Kristin Ollis, William Craigo, Zhili Sun, Michael C Matelich, Jorge E. Gomez-Galeno, James M. Fujitaki, K. Raja Reddy, Bheemarao G Ugarkar
Publikováno v:
Journal of medicinal chemistry. 51(3)
Adefovir dipivoxil, a marketed drug for the treatment of hepatitis B, is dosed at submaximally efficacious doses because of renal toxicity. In an effort to improve the therapeutic index of adefovir, 1-aryl-1,3-propanyl prodrugs were synthesized with
Autor:
Serge H. Boyer, Mark D. Erion, Bheemarao G. Ugarkar, Joel Solbach, Rohan Mendonca, Joseph J. Kopcho, Atsushi Nagahisa, and James B. Wiesner, Michael C. Matelich, Megumi Tsuchiya, Kristin Ollis, Jorge Gomez-Galeno, Masami Nakane
Publikováno v:
Journal of medicinal chemistry. 48(20)
Adenosine is an endogenous neuromodulator that when produced in the central and the peripheral nervous systems has anticonvulsant, anti-inflammatory, and analgesic properties. However, efforts to use adenosine receptor agonists are plagued by dose-li
Autor:
Thomas Daniel Aicher, Keith R. Buszek, Craig J. Forsyth, Suk Kyoon Yoon, Francis G. Fang, Michael C. Matelich, Denice M. Spero, Paul Michael Scola, Yoshito Kishi, Sun Ho Jung
Publikováno v:
Journal of the American Chemical Society. 114:3162-3164
Autor:
Barry M. Trost, Michael C. Matelich
Publikováno v:
Journal of the American Chemical Society. 113:9007-9009
Autor:
K. Raja Reddy, Michael C. Matelich, Bheemarao G. Ugarkar, Jorge E. Gómez-Galeno, Jay DaRe, Kristin Ollis, Zhili Sun, William Craigo, Timothy J. Colby, James M. Fujitaki, Serge H. Boyer, Paul D. van Poelje, Mark D. Erion
Publikováno v:
Journal of Medicinal Chemistry; Jan2008, Vol. 51 Issue 3, p666-676, 11p