Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Michael C. Humble"'
Autor:
Christine G. Parks, Frederick W. Miller, Kenneth Michael Pollard, Carlo Selmi, Dori Germolec, Kelly Joyce, Noel R. Rose, Michael C. Humble
Publikováno v:
International Journal of Molecular Sciences, Vol 15, Iss 8, Pp 14269-14297 (2014)
Autoimmune diseases include 80 or more complex disorders characterized by self-reactive, pathologic immune responses in which genetic susceptibility is largely insufficient to determine disease onset. In September 2010, the National Institute of Envi
Externí odkaz:
https://doaj.org/article/3846d733c62f48789794261128aeb777
Autor:
Noel R. Rose, Dori R. Germolec, Frederick W. Miller, Carlo Selmi, Kelly Joyce, Kenneth Michael Pollard, Michael C. Humble, Christine G. Parks
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 15, Iss 8, Pp 14269-14297 (2014)
International Journal of Molecular Sciences, Vol 15, Iss 8, Pp 14269-14297 (2014)
Autoimmune diseases include 80 or more complex disorders characterized by self-reactive, pathologic immune responses in which genetic susceptibility is largely insufficient to determine disease onset. In September 2010, the National Institute of Envi
Autor:
Carlo Selmi, Frederick W. Miller, Michael C. Humble, Christine G. Parks, Dori R. Germolec, Noel R. Rose, Patrick S.C. Leung, K. Michael Pollard
Publikováno v:
Journal of Autoimmunity. 39:253-258
Increasing evidence supports a role for the environment in the development of autoimmune diseases, as reviewed in the accompanying three papers from the National Institute of Environmental Health Sciences Expert Panel Workshop. An important unresolve
Publikováno v:
Reproductive Toxicology. 31:327-336
There is now compelling evidence that developmental exposure to chemicals from our environment contributes to disease later in life, with animal models supporting this concept in reproductive, metabolic, and neurodegenerative diseases. In contrast, d
Autor:
Valentina Di Francesco, Jean E. McEwen, Carl C. Baker, Jeffery A. Schloss, Samir Zakhari, Susan Garges, Bracie Watson, Tsegahiwot Belachew, Kris A. Wetterstrand, Matthew E. Portnoy, Michael H. Sayre, A. Roger Little, Beena Akolkar, Carolyn Deal, Lindsey Grandison, Jane Peterson, Michael Wright, Lisa Begg, Jag H. Khalsa, Pamela Starke-Reed, Rachelle Salomon, Jennifer S. Read, Hannah Peavy, Robert W. Karp, T. Kevin Howcroft, Christina Giblin, Chris Mullins, Cindy D. Davis, Pamela McInnes, Christopher Wellington, Lu Wang, R. Dwayne Lunsford, Melody Mills, Hagit David, Maria Y. Giovanni, Carol H. Pontzer, Vivien Bonazzi, Michael C. Humble, Mark S. Guyer
Publikováno v:
The Human Microbiota
The Human Microbiome Project (HMP), funded as an initiative of the NIH Roadmap for Biomedical Research (http://nihroadmap.nih.gov), is a multi-component community resource. The goals of the HMP are: (1) to take advantage of new, high-throughput techn
Autor:
Ronald E. Cannon, Joan P. Graves, Vladimir Larionov, Natalya Kouprina, Vladimir N. Noskov, Raymond W. Tennant, Michael C. Humble, Michael A. Resnick, Ed Garner
Publikováno v:
Genomics. 70:292-299
Transformation-associated recombination (TAR) cloning allows entire genes and large chromosomal regions to be specifically, accurately, and quickly isolated from total genomic DNA. We report the first example of radial TAR cloning from the mouse geno
Autor:
Dori R. Germolec, Alessandra Bruccoleri, Michael I. Luster, Michael C. Humble, Judson W. Spalding, G.S. Chen, Gary A. Boorman, Petia P. Simeonova, Takahiko Yoshida, Julie F. Foley, Hsin-Su Yu
Publikováno v:
The American Journal of Pathology. 153:1775-1785
Although numerous epidemiological studies have shown that inorganic arsenicals cause skin cancers and hyperkeratoses in humans, there are currently no established mechanisms for their action or animal models. Previous studies in our laboratory using
Autor:
David C. Lee, Ronald E. Cannon, Carl J. Szczesniak, Michael C. Humble, Laura A. Hansen, Noreen C. Luetteke, Judson W. Spalding, Raymond W. Tennant
Publikováno v:
Toxicologic Pathology. 26:562-569
Alterations in growth factor signaling pathways frequently accompany the development and maintenance of epithelial neoplasia. Transforming growth factor alpha (TGF alpha) and its epidermal growth factor receptor have been thought to play an especiall
Autor:
Michael C. Humble, Judson W. Spalding, Raymond W. Tennant, Randall S. Faircloth, Gregory D. Lacks, Kelly M. Virgil, Ronald E. Cannon
Publikováno v:
Molecular Carcinogenesis. 21:244-250
Tg.AC transgenic mice have a transgene composed of a zeta-globin transcriptional control region, a v-Ha-ras coding region, and a simian virus 40 3' polyadenylation signal sequence. Induced ectopic expression of the transgene by chemical treatment or
Autor:
Kelly M. Virgil, Ronald E. Cannon, Judson W. Spalding, Raymond W. Tennant, Michael C. Humble, Carl J. Szczesniak, Carol S. Trempus
Publikováno v:
Molecular Carcinogenesis. 20:108-114
The Tg.AC transgenic mouse, which harbors an activated v-Ha-ras coding region that is fused to an embryonic zeta globin transcriptional control region and a 3' simian virus 40 polyadenylation sequence, rapidly develops epidermal papillomas in respons