Zobrazeno 1 - 10
of 163
pro vyhledávání: '"Michael C. Hogan"'
Publikováno v:
J Appl Physiol (1985)
One of the most important cytosolic Ca(2+) buffers present in mouse fast-twitch myofibers, but not in human myofibers, is parvalbumin (PV). Previous work using conventional PV gene (PV) knockout (PV-KO) mice suggests that lifelong PV ablation increas
Autor:
Alejandra Garate-Carrillo, Alonso Rodriguez, Claudia C. Calzada-Mendoza, Viridiana Navarrete-Yañez, Michael C. Hogan, Israel Ramirez-Sanchez, Patricia Mendoza-Lorenzo, Guillermo Ceballos, Francisco Villarreal
Publikováno v:
Food Funct
Evidence has implicated oxidative stress (OS) and inflammation as drivers of neurodegenerative pathologies. We previously reported on the beneficial effects of (-)-epicatechin (Epi) treatment on aging-induced OS and its capacity to restore modulators
Autor:
Scott K. Powers, Michael C. Hogan
Publikováno v:
The Journal of physiologyReferences. 599(3)
Upon a sudden rise in work rate, ATP turnover increases immediately, whereas the adjustment of ATP resynthesis from oxidative phosphorylation is substantially slower. An "O2 deficit" (energy borrowed from substrate level phosphorylation) is therefore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d5573877f0a39dbcea3c5a4d4415a10
http://hdl.handle.net/11390/1194574
http://hdl.handle.net/11390/1194574
Autor:
L. Bruce Gladden, Simone Porcelli, Andreas N. Kavazis, James R. McDonald, Michael C. Hogan, Brian S. Ferguson, Bruno Grassi, Letizia Rasica
Publikováno v:
J Physiol
Key points Increased plasma nitrite concentrations may have beneficial effects on skeletal muscle function. The physiological basis explaining these observations has not been clearly defined and it may involve positive effects on muscle contraction f
Publikováno v:
The Journal of Physiology. 596:1079-1089
Key points Skeletal muscle contractile activity is associated with an enhanced reactive oxygen species (ROS) generation. At very low PO2, ROS generation by mitochondria can be elevated in intact cells. An elevated intracellular oxidant activity may a
Autor:
Steven D Mason, Richard A Howlett, Matthew J Kim, I Mark Olfert, Michael C Hogan, Wayne McNulty, Reed P Hickey, Peter D Wagner, C Ronald Kahn, Frank J Giordano, Randall S Johnson
Publikováno v:
PLoS Biology, Vol 2, Iss 10, p e288 (2004)
The physiological flux of oxygen is extreme in exercising skeletal muscle. Hypoxia is thus a critical parameter in muscle function, influencing production of ATP, utilization of energy-producing substrates, and manufacture of exhaustion-inducing meta
Externí odkaz:
https://doaj.org/article/32adb9c80a7d42adabde5991d4f218bf
Autor:
Leonardo Nogueira, Stephen J. Bailey, Michael C. Hogan, Paulo Guimarães Gandra, Andrew M. Jones
Publikováno v:
The Journal of Physiology. 598:1643-1644
Autor:
Michael C. Hogan, Leonardo Nogueira, Andrew M. Jones, Paulo Guimarães Gandra, Stephen J. Bailey
Publikováno v:
The Journal of physiology. 597(22)
KEY POINTS Dietary nitrate supplementation increases plasma nitrite concentration, which provides an oxygen-independent source of nitric oxide and can delay skeletal muscle fatigue. Nitrate supplementation has been shown to increase myofibre calcium
Autor:
Michael C. Hogan
Publikováno v:
The Journal of Physiology. 599:1005-1005