Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Michael C. Goodman"'
Autor:
Qiyi He, Mark R. McCoy, Meng Qi, Christophe Morisseau, Huiyi Yang, Chengpeng Xu, Rachel Shey, Michael C. Goodman, Suqing Zhao, Bruce D. Hammock
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 19, p 14698 (2023)
A microsomal epoxide hydrolase (mEH) metabolizes in vivo in both xenobiotic and endogenous epoxides associated with signaling function. Findings in patients suggest that mEH might be a biomarker for several diseases, including metastatic cancer and v
Externí odkaz:
https://doaj.org/article/176413cef79d4c5586cf704d4e4311bc
Autor:
James A. Wepy, James J. Galligan, Philip J. Kingsley, Shu Xu, Michael C. Goodman, Keri A. Tallman, Carol A. Rouzer, Lawrence J. Marnett
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 2, Pp 360-374 (2019)
Lysophospholipids (LysoPLs) are bioactive lipid species involved in cellular signaling processes and the regulation of cell membrane structure. LysoPLs are metabolized through the action of lysophospholipases, including lysophospholipase A1 (LYPLA1)
Externí odkaz:
https://doaj.org/article/0c7818f0335641b48676fb4d1755eadf
Autor:
James A. Wepy, James J. Galligan, Phillip J. Kingsley, Shu Xu, Michael C. Goodman, Keri A. Tallman, Carol A. Rouzer, Lawrence J. Marnett
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 7, Pp 1345- (2019)
Externí odkaz:
https://doaj.org/article/29173cf4abfa41bcbc53449a409383d3
Autor:
Surajit Banerjee, Michael C. Goodman, Shu Xu, Marco Migliore, Lawrence J. Marnett, Daniele Piomelli, Carol A. Rouzer, Kebreab Ghebreselasie
Publikováno v:
Journal of Biological Chemistry. 293:3028-3038
The cyclooxygenases COX-1 and COX-2 oxygenate arachidonic acid (AA) to prostaglandin H(2) (PGH(2)). COX-2 also oxygenates the endocannabinoids 2-arachidonoylglycerol (2-AG) and arachidonoylethanolamide (AEA) to the corresponding PGH(2) analogs. Both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eff02d3b4cb11fef6430740a5607295
https://doi.org/10.1074/jbc.m117.802058
https://doi.org/10.1074/jbc.m117.802058
Autor:
Richard N. Armstrong, Michael C. Goodman, Eric P. Skaar, Kevin L. Jagessar, Paul D. Cook, Matthew K. Thompson, Mary E. Keithly, Neal D. Hammer, Joel M. Harp
Publikováno v:
Biochemistry
The Gram-positive pathogen Staphylococcus aureus is a leading cause of global morbidity and mortality. Like many multi-drug-resistant organisms, S. aureus contains antibiotic-modifying enzymes that facilitate resistance to a multitude of antimicrobia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ec2eac84a11923a07f176e5af6fe0b7
https://doi.org/10.1021/bi4015852
https://doi.org/10.1021/bi4015852
Publikováno v:
Biochemistry. 52:5790-5799
NorM of the multidrug and toxic compound extrusion (MATE) family of transporters couples the efflux of a broad range of hydrophobic molecules to an inward Na⁺ gradient across the cell membrane. Several crystal structures of MATE transporters reveal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3a17ce3435c409f4811ad2dab4539ce
https://doi.org/10.1021/bi4008935
https://doi.org/10.1021/bi4008935
Autor:
Bengt Samuelsson, Joseph Brock, Michael C. Goodman, Navisraj Balagunaseelan, Agnes Rinaldo-Matthis, Emilia Strandback, Mats Hamberg, Jesper Z. Haeggström, Ralf Morgenstern
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 113(4)
Microsomal prostaglandin E2 synthase type 1 (mPGES-1) is responsible for the formation of the potent lipid mediator prostaglandin E2 under proinflammatory conditions, and this enzyme has received considerable attention as a drug target. Recently, a h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7f02e809221ebdf9e4b82ca4655e7a9
https://pubmed.ncbi.nlm.nih.gov/26755582
https://pubmed.ncbi.nlm.nih.gov/26755582
Autor:
Per-Johan Jakobsson, Filip Bergqvist, Michael C. Goodman, Linda Spahiu, Helena Idborg, Ralf Morgenstern, Joan Raouf, Nazmi Rafique, Richard N. Armstrong
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163600 (2016)
PLoS ONE
PLoS ONE
Introduction Prostaglandins are signaling molecules that regulate different physiological processes, involving allergic and inflammatory responses and cardiovascular control. They are involved in several pathophysiological processes, including inflam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e79998651855d4ec0785d0fd1977c8d
http://europepmc.org/articles/PMC5042469?pdf=render
http://europepmc.org/articles/PMC5042469?pdf=render
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose Lens glutathione synthesis knockout (LEGSKO) mouse lenses lack de novo glutathione (GSH) synthesis but still maintain >1 mM GSH. We sought to determine the source of this residual GSH and the mechanism by which it accumulates in the lens. Met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c3b9e7767d7c432a451da7f61f7fecc
https://doi.org/10.1167/iovs.16-19592
https://doi.org/10.1167/iovs.16-19592
Autor:
Eric A. Grulke, Michael T. Tseng, Uschi M. Graham, Peng Wu, Jason M. Unrine, Robert A. Yokel, D. Allan Butterfield, Michael C. Goodman, Tu C. Au, Mo Dan, Sarita S. Hardas, Hamed Haghnazar, Rukhsana Sultana, Robert C. MacPhail
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 127(1)
Nanoceria is used as a catalyst in diesel fuel, as an abrasive in printed circuit manufacture, and is being pursued as an antioxidant therapeutic. Our objective is to extend previous findings showing that there were no reductions of cerium in organs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80c753daab88d3cf5c87ed78b9b396f4
https://pubmed.ncbi.nlm.nih.gov/22367688
https://pubmed.ncbi.nlm.nih.gov/22367688