Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Michael C. Dyle"'
Autor:
Amy E. Campbell, Michael C. Dyle, Roberto Albanese, Tyler Matheny, Kavitha Sudheendran, Michael A. Cortázar, Thomas Forman, Rui Fu, Austin E. Gillen, Marvin H. Caruthers, Stephen N. Floor, Lorenzo Calviello, Sujatha Jagannathan
Publikováno v:
Cell Reports, Vol 42, Iss 6, Pp 112642- (2023)
Summary: Nonsense-mediated RNA decay (NMD) degrades transcripts carrying premature termination codons. NMD is thought to prevent the synthesis of toxic truncated proteins. However, whether loss of NMD results in widespread production of truncated pro
Externí odkaz:
https://doaj.org/article/df0dd2523a6149e2baba95596b1500ad
Autor:
Arpit Sharma, Lalita Oonthonpan, Ryan D Sheldon, Adam J Rauckhorst, Zhiyong Zhu, Sean C Tompkins, Kevin Cho, Wojciech J Grzesik, Lawrence R Gray, Diego A Scerbo, Alvin D Pewa, Emily M Cushing, Michael C Dyle, James E Cox, Chris Adams, Brandon S Davies, Richard K Shields, Andrew W Norris, Gary Patti, Leonid V Zingman, Eric B Taylor
Publikováno v:
eLife, Vol 8 (2019)
Metabolic cycles are a fundamental element of cellular and organismal function. Among the most critical in higher organisms is the Cori Cycle, the systemic cycling between lactate and glucose. Here, skeletal muscle-specific Mitochondrial Pyruvate Car
Externí odkaz:
https://doaj.org/article/13cd1adfdce945bdbb60969f1404d117
Autor:
Tai Huang, Michael C. Dyle, Nicole M. Gensicke, Lan Qian, Nicholas D. Andersen, Nicholas B. Cavanaugh, Joseph W. Turek
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 159:1719-1726
Objective Marfan syndrome (MFS) represents a genetic disorder with a range of clinical features, including proximal aortic aneurysms. Extensive research has revealed an abundance of transforming growth factor beta from a mutation in fibrillin-1 to be
Autor:
Amy E. Campbell, Michael C. Dyle, Lorenzo Calviello, Tyler Matheny, Kavitha Sudheendran, Michael A. Cortazar, Thomas Forman, Rui Fu, Austin E. Gillen, Marvin H. Caruthers, Stephen N. Floor, Sujatha Jagannathan
Nonsense-mediated RNA decay (NMD) is a surveillance mechanism that degrades both canonical and aberrant transcripts carrying premature translation termination codons. NMD is thought to have evolved to prevent the synthesis of toxic truncated proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47d1e35295b3d46515ea341d82d00715
https://doi.org/10.1101/2021.06.28.450189
https://doi.org/10.1101/2021.06.28.450189
Autor:
Steven D Kunkel, Christopher J Elmore, Kale S Bongers, Scott M Ebert, Daniel K Fox, Michael C Dyle, Steven A Bullard, Christopher M Adams
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39332 (2012)
Skeletal muscle Akt activity stimulates muscle growth and imparts resistance to obesity, glucose intolerance and fatty liver disease. We recently found that ursolic acid increases skeletal muscle Akt activity and stimulates muscle growth in non-obese
Externí odkaz:
https://doaj.org/article/03afc48475714e049b8048a5ea5d18c7
Publikováno v:
Current Opinion in Clinical Nutrition & Metabolic Care. 20:164-168
Here, we discuss recent work focused on the role of activating transcription factor 4 (ATF4) in skeletal muscle atrophy.Muscle atrophy involves and requires widespread changes in skeletal muscle gene expression; however, the transcriptional regulator
Autor:
Eric B. Taylor, Kevin Cho, Emily M. Cushing, Christopher M. Adams, Brandon S.J. Davies, Gary J. Patti, James E. Cox, Diego A Scerbo, Zhiyong Zhu, Lawrence R. Gray, Adam J. Rauckhorst, Wojciech J. Grzesik, Richard K. Shields, Michael C. Dyle, Arpit Sharma, Lalita Oonthonpan, Sean C. Tompkins, Andrew W. Norris, Leonid V. Zingman, Ryan D. Sheldon, Alvin D. Pewa
Publikováno v:
eLife, Vol 8 (2019)
eLife
eLife
Metabolic cycles are a fundamental element of cellular and organismal function. Among the most critical in higher organisms is the Cori Cycle, the systemic cycling between lactate and glucose. Here, skeletal muscle-specific Mitochondrial Pyruvate Car
Autor:
Lawrence R. Gray, Michael C. Dyle, Kevin Cho, Andrew W. Norris, Arpit Sharma, Alvin D. Pewa, Eric B. Taylor, Emily M. Cushing, Christopher M. Adams, Adam J. Rauckhorst, Leonid V. Zingman, Zhiyong Zhu, Sean C. Tompkins, Lalita Oonthonpan, Richard K. Shields, Ryan D. Sheldon, Wojciech J. Grzesik, Diego A Scerbo, Brandon S.J. Davies, James E. Cox, Gary J. Patti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6fd7c09a9ed6c3c31f52227e1340afa
https://doi.org/10.7554/elife.45873.027
https://doi.org/10.7554/elife.45873.027
Publikováno v:
Wiley interdisciplinary reviews. RNAREFERENCES. 11(1)
Nonsense-mediated RNA decay (NMD) is an evolutionarily conserved RNA quality control process that serves both as a mechanism to eliminate aberrant transcripts carrying premature stop codons, and to regulate expression of some normal transcripts. For
Autor:
Svyatoslav Dvoretskiy, Michael Munroe, Jiayu Leong, Amber Lopez, Christopher M. Adams, Marni D. Boppart, Michael C. Dyle, Hyunjoon Kong
Conditions of extended bed rest and limb immobilization can initiate rapid and significant loss of skeletal muscle mass and function. Physical rehabilitation is standard practice following a period of disuse, yet mobility may be severely compromised,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2287f40faab31941f6186379dd98d18
https://europepmc.org/articles/PMC6529341/
https://europepmc.org/articles/PMC6529341/