Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Michael C. Cox"'
Autor:
Michael C. Cox, Matthew Booth, Gabriela Ghita, Zhongkai Wang, Anna Gardner, Russell B. Hawkins, Dijoia B. Darden, Christiaan Leeuwenburgh, Lyle L. Moldawer, Frederick A. Moore, Philip A. Efron, Steven Anton, Scott C. Brakenridge
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 5, Pp 1203-1213 (2021)
Abstract Background Sarcopenia is a known risk factor for poor outcomes across many chronic diseases. The impact on outcomes of both pre‐existing sarcopenia and acute muscle wasting (AMW) in acute critical illness caused by sepsis remain unclear. M
Externí odkaz:
https://doaj.org/article/16684d1961b74cc18f2945b2599e2cd8
Autor:
Julie A. Stortz, Michael C. Cox, Russell B. Hawkins, Gabriela L. Ghita, Babette A. Brumback, Alicia M. Mohr, Lyle L. Moldawer, Philip A. Efron, Scott C. Brakenridge, Frederick A. Moore
Publikováno v:
Critical Care, Vol 24, Iss 1, Pp 1-14 (2020)
Abstract Background The role of site of infection in sepsis has been poorly characterized. Additionally, sepsis epidemiology has evolved. Early mortality has decreased, but many survivors now progress into chronic critical illness (CCI). This study s
Externí odkaz:
https://doaj.org/article/bba633b1269345548fba33368a6cfaaa
Autor:
McKenzie K. Hollen, Julie A. Stortz, Dijoia Darden, Marvin L. Dirain, Dina C. Nacionales, Russell B. Hawkins, Michael C. Cox, Maria-Cecilia Lopez, Jaimar C. Rincon, Ricardo Ungaro, Zhongkai Wang, Quran Wu, Babette Brumback, Marie-Pierre L. Gauthier, Michael Kladde, Christiaan Leeuwenburgh, Mark Segal, Azra Bihorac, Scott Brakenridge, Frederick A. Moore, Henry V. Baker, Alicia M. Mohr, Lyle L. Moldawer, Philip A. Efron
Publikováno v:
Critical Care, Vol 23, Iss 1, Pp 1-16 (2019)
Abstract Background Sepsis is an increasingly significant challenge throughout the world as one of the major causes of patient morbidity and mortality. Central to the host immunologic response to sepsis is the increase in circulating myeloid-derived
Externí odkaz:
https://doaj.org/article/6b9df6c997a446a79a45c0e33340dd88
Autor:
Dijoia B. Darden, Julie A. Stortz, McKenzie K. Hollen, Michael C. Cox, Camille G. Apple, Russell B. Hawkins, Jaimar C. Rincon, Maria-Cecilia Lopez, Zhongkai Wang, Eduardo Navarro, Jennifer E. Hagen, Hari K. Parvataneni, Maigan A. Brusko, Michael Kladde, Rhonda Bacher, Babette A. Brumback, Scott C. Brakenridge, Henry V. Baker, Christopher R. Cogle, Alicia M. Mohr, Philip A. Efron
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Older adults have significantly worse morbidity and mortality after severe trauma than younger cohorts. The competency of the innate immune response decreases with advancing age, especially after an inflammatory insult. Subsequent poor outcomes after
Externí odkaz:
https://doaj.org/article/0800739a2ae74d9f9aa89d5799441eb9
Autor:
Dijoia B. Darden, Gabriela L. Ghita, Zhongkai Wang, Julie A. Stortz, Maria-Cecilia Lopez, Michael C. Cox, Russell B. Hawkins, Jaimar C. Rincon, Lauren S. Kelly, Brittany P. Fenner, Tezcan Ozrazgat-Baslanti, Christiaan Leeuwenburgh, Azra Bihorac, Tyler J. Loftus, Frederick A. Moore, Scott C. Brakenridge, Henry V. Baker, Rhonda Bacher, Alicia M. Mohr, Lyle L. Moldawer, Philip A. Efron
Publikováno v:
Journal of Clinical Medicine, Vol 10, Iss 15, p 3211 (2021)
Surgical sepsis has evolved into two major subpopulations: patients who rapidly recover, and those who develop chronic critical illness (CCI). Our primary aim was to determine whether CCI sepsis survivors manifest unique blood leukocyte transcriptome
Externí odkaz:
https://doaj.org/article/45388e6611df4968b051372eba23613d
Autor:
Matthew M. Booth, Zhongkai Wang, Frederick A. Moore, Russell B. Hawkins, Anna K Gardner, Scott C. Brakenridge, Philip A. Efron, Christiaan Leeuwenburgh, Steven D Anton, Michael C. Cox, Lyle L. Moldawer, Dijoia B Darden, Gabriela L. Ghita
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle
Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 5, Pp 1203-1213 (2021)
Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 5, Pp 1203-1213 (2021)
Background Sarcopenia is a known risk factor for poor outcomes across many chronic diseases. The impact on outcomes of both pre‐existing sarcopenia and acute muscle wasting (AMW) in acute critical illness caused by sepsis remain unclear. Methods We
Autor:
Scott C. Brakenridge, Alicia M. Mohr, Frederick A. Moore, Philip A. Efron, Russell B. Hawkins, Julie A. Stortz, Michael C. Cox, Gabriela L. Ghita, Lyle L. Moldawer, Dijoa B. Darden
Publikováno v:
Am J Surg
Background As hospital sepsis mortality has decreased, more surgical ICU survivors are progressing into chronic critical illness (CCI). This study documents the incidence of CCI and long-term outcomes of patients with abdominal sepsis. We hypothesize
Autor:
Ulrike Gerdemann, Steve Smith, Michael C. Cox, A. Lindsay Frazier, Peter M. Anderson, Sandya Govinda Raju, Julia Glade Bender, S. Michael Rothenberg, Alberto S. Pappo, Michael V. Ortiz, Dahlia Henry, Stéphanie Proust
Publikováno v:
JCO Precision Oncology
Autor:
Robert T. Mankowski, Dina C. Nacionales, Lyle L. Moldawer, Thomas L. Clanton, Raad Z. Gharaibeh, Scott C. Brakenridge, Dijoia B Darden, Alicia M. Mohr, Philip A. Efron, F. A. Moore, Christiaan Leeuwenburgh, Russell B. Hawkins, Marvin L. Dirain, Camille G Apple, Michael C. Cox, Orlando Laitano, Ricardo Ungaro, Ryan M. Thomas
Publikováno v:
Shock
Background Older adults have worse outcomes after sepsis than young adults. Additionally, alterations of the gut microbiota have been demonstrated to contribute to sepsis-related mortality. We sought to determine if there were alterations in the gut
Autor:
Alicia M. Mohr, Michael C. Cox, Philip A. Efron, Lyle L. Moldawer, Frederick A. Moore, Scott C. Brakenridge, Babette Brumback, Christiaan Leeuwenburgh, Robert T. Mankowski, Gabriela L. Ghita, Stephen D. Anton
Publikováno v:
J Am Geriatr Soc
Objectives Sepsis has been called a "disease of the elderly," and as in-hospital mortality has decreased, more sepsis survivors are progressing into poorly characterized long-term outcomes. The purpose of this study was to describe the current epidem