Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Michael C. Condro"'
Autor:
Alireza Sohrabi, Austin E.Y.T. Lefebvre, Mollie J. Harrison, Michael C. Condro, Talia M. Sanazzaro, Gevick Safarians, Itay Solomon, Soniya Bastola, Shadi Kordbacheh, Nadia Toh, Harley I. Kornblum, Michelle A. Digman, Stephanie K. Seidlits
Publikováno v:
Cell Reports, Vol 42, Iss 10, Pp 113175- (2023)
Summary: The mechanical properties of solid tumors influence tumor cell phenotype and the ability to invade surrounding tissues. Using bioengineered scaffolds to provide a matrix microenvironment for patient-derived glioblastoma (GBM) spheroids, this
Externí odkaz:
https://doaj.org/article/d2250eca7fe7426383653643a3dc60db
Autor:
Sree Deepthi Muthukrishnan, Riki Kawaguchi, Pooja Nair, Rachna Prasad, Yue Qin, Maverick Johnson, Qing Wang, Nathan VanderVeer-Harris, Amy Pham, Alvaro G. Alvarado, Michael C. Condro, Fuying Gao, Raymond Gau, Maria G. Castro, Pedro R. Lowenstein, Arjun Deb, Jason D. Hinman, Frank Pajonk, Terry C. Burns, Steven A. Goldman, Daniel H. Geschwind, Harley I. Kornblum
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Therapeutic stress induces phenotypic plasticity in glioma stem cells although the mechanisms underlying this remain poorly understood. Here, the authors show that P300 mediates the radiation-induced vascular-like conversion of glioma stem cells to p
Externí odkaz:
https://doaj.org/article/2f813af486a84bc6939ddacebcf2e7f8
Autor:
Jiwen Li, Lin Pan, William G. Pembroke, Jessica E. Rexach, Marlesa I. Godoy, Michael C. Condro, Alvaro G. Alvarado, Mineli Harteni, Yen-Wei Chen, Linsey Stiles, Angela Y. Chen, Ina B. Wanner, Xia Yang, Steven A. Goldman, Daniel H. Geschwind, Harley I. Kornblum, Ye Zhang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Astrocytes are important players in brain development, homeostasis, and disease. Here, the authors compare the transcriptional profiles of human and mouse astrocytes. They report species-specific susceptibility to oxidative stress and response to hyp
Externí odkaz:
https://doaj.org/article/80da4dfa224845c2a806b159e42df65d
Autor:
Christina Van, Michael C. Condro, Henly H. Ko, Anh Q. Hoang, Ruoyan Zhu, Kenny Lov, Patrick T. Ricaflanca, Anna L. Diep, Nhat N.M. Nguyen, Gerald S. Lipshutz, Allan MacKenzie-Graham, James A. Waschek
Publikováno v:
Neurobiology of Disease, Vol 160, Iss , Pp 105524- (2021)
Chronic inflammation drives synaptic loss in multiple sclerosis (MS) and is also commonly observed in other neurodegenerative diseases. Clinically approved treatments for MS provide symptomatic relief but fail to halt neurodegeneration and neurologic
Externí odkaz:
https://doaj.org/article/66958102771743ab9562848a5c15b89c
Autor:
Jantzen Sperry, Michael C. Condro, Lea Guo, Daniel Braas, Nathan Vanderveer-Harris, Kristen K.O. Kim, Whitney B. Pope, Ajit S. Divakaruni, Albert Lai, Heather Christofk, Maria G. Castro, Pedro R. Lowenstein, Janel E. Le Belle, Harley I. Kornblum
Publikováno v:
iScience, Vol 23, Iss 9, Pp 101453- (2020)
Summary: Glioblastoma (GBM) metabolism has traditionally been characterized by a primary dependence on aerobic glycolysis, prompting the use of the ketogenic diet (KD) as a potential therapy. In this study we evaluated the effectiveness of the KD in
Externí odkaz:
https://doaj.org/article/c408bc708ce74fd297a8a89e0dcb76f3
Autor:
Michael C. Condro, Stephanie A. White
Publikováno v:
Comparative Cognition & Behavior Reviews, Vol 9, Pp 74-97 (2014)
Externí odkaz:
https://doaj.org/article/39a7853ab145452c98d07e3e2c39d3a3
Autor:
Gevick Safarians, Alireza Sohrabi, Itay Solomon, Weikun Xiao, Soniya Bastola, Bushra W. Rajput, Mary Epperson, Isabella Rosenzweig, Kelly Tamura, Breahna Singer, Joyce Huang, Mollie J. Harrison, Talia Sanazzaro, Michael C. Condro, Harley I. Kornblum, Stephanie K. Seidlits
Publikováno v:
Advanced healthcare materials, vol 12, iss 14
Adv Healthc Mater
Adv Healthc Mater
Increased secretion of hyaluronic acid (HA), a glycosaminoglycan abundant in the brain extracellular matrix (ECM), correlates with worse clinical outcomes for glioblastoma (GBM) patients. GBM cells aggressively invade the brain parenchyma while encou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd1f1ffa133db5e6799a899e5488e924
https://escholarship.org/uc/item/4884w8bj
https://escholarship.org/uc/item/4884w8bj
Autor:
Yukio Ago, Christina Van, Michael C. Condro, Haley Hrncir, Anna L. Diep, Abha K. Rajbhandari, Michael S. Fanselow, Hitoshi Hashimoto, Allan J. MacKenzie-Graham, James A. Waschek
Publikováno v:
Experimental Neurology. 362:114339
Autor:
Yasmin Ghochani, Sree Deepthi Muthukrishnan, Alireza Sohrabi, Riki Kawaguchi, Michael C. Condro, Soniya Bastola, Fuying Gao, Yue Qin, Jack Mottahedeh, M. Luisa Iruela-Arispe, Nagesh Rao, Dan R. Laks, Linda M. Liau, Gary W. Mathern, Steven A. Goldman, S. Thomas Carmichael, Ichiro Nakano, Giovanni Coppola, Stephanie K. Seidlits, Harley I. Kornblum
Publikováno v:
Ghochani, Y, Muthukrishnan, S D, Sohrabi, A, Kawaguchi, R, Condro, M C, Bastola, S, Gao, F, Qin, Y, Mottahedeh, J, Iruela-Arispe, M L, Rao, N, Laks, D R, Liau, L M, Mathern, G W, Goldman, S A, Carmichael, S T, Nakano, I, Coppola, G, Seidlits, S K & Kornblum, H I 2022, ' A molecular interactome of the glioblastoma perivascular niche reveals integrin binding sialoprotein as a mediator of tumor cell migration ', Cell Reports, vol. 41, no. 3, 111511 . https://doi.org/10.1016/j.celrep.2022.111511
Cell reports, vol 41, iss 3
Cell reports, vol 41, iss 3
Glioblastoma (GBM) is characterized by extensive microvascular hyperproliferation. In addition to supplying blood to the tumor, GBM vessels also provide trophic support to glioma cells and serve as conduits for migration into the surrounding brain, p
Autor:
Stephanie K. Seidlits, Ichiro Nakano, Harley I. Kornblum, Giovanni Coppola, Soniya Bastola, Linda M. Liau, Alireza Sohrabi, Yasmin Ghochani, Jack Mottahedeh, Steven A. Goldman, Riki Kawaguchi, Gary W. Mathern, S. Thomas Carmichael, Yue Qin, Nagesh Rao, Fuying Gao, Dan R. Laks, M. Luisa Iruela Arispe, Sree Deepthi Muthukrishnan, Michael C. Condro
SummaryGlioblastoma (GBM) is characterized by extensive microvascular hyperproliferation. In addition to supplying blood to the tumor, GBM vessels also provide trophic support to glioma cells and serve as conduits for migration into the surrounding b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20a5865842c89659e921126749fafdd7
https://doi.org/10.1101/2021.10.01.462643
https://doi.org/10.1101/2021.10.01.462643