Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Michael C. Carakostas"'
Publikováno v:
Food and Chemical Toxicology. 75:71-78
Steviol glycoside sweeteners are extracted from the plant Stevia rebaudiana (Bertoni), a member of the Asteraceae (Compositae) family. Many plants from this family can induce hypersensitivity reactions via multiple routes of exposure (e.g., ragweed,
Autor:
Christopher R. Kirman, Deborah M. Proctor, Mina Suh, Laurie C. Haws, Mark A. Harris, Chad M. Thompson, Michael C. Carakostas
Publikováno v:
Food and Chemical Toxicology. 65:381-388
Hexavalent chromium [Cr(VI)] induces hematological signs of microcytic anemia in rodents. Considering that Cr(VI) can oxidize ferrous (Fe(2+)) to ferric (Fe(3+)) iron, and that only the former is transported across the duodenum, we hypothesize that,
Autor:
Andrew G. Renwick, Bernadene A. Magnuson, Michael C. Carakostas, Sylvia P. Poulos, Nadia H. Moore
Publikováno v:
Nutrition reviews. 74(11)
With continued efforts to find solutions to rising rates of obesity and diabetes, there is increased interest in the potential health benefits of the use of low- and no-calorie sweeteners (LNCSs). Concerns about safety often deter the use of LNCSs as
Autor:
Nicole Cuellar-Kingston, Alex K. Eapen, George Pugh, Rebecca Rogerson, Hua Kern, Christine M. Crincoli, Ashley Roberts, Andrew G. Renwick, Matthew Coffee, Barry Lynch, Sachin Bhusari, Sidd Purkayastha, Michael C. Carakostas
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 79
The acceptable daily intake (ADI) of commercially available steviol glycosides is currently 0–4 mg/kg body weight (bw)/day, based on application of a 100-fold uncertainty factor to a no-observed-adverse-effect-level value from a chronic rat study.
Autor:
J. Andrew Tachovsky, Chad M. Thompson, Camarie Perry, David W. Gaylor, Michael C. Carakostas, Laurie C. Haws
Publikováno v:
Journal of Applied Toxicology. 33:1395-1406
Sulfolane is a widely used industrial solvent that is often used for gas treatment (sour gas sweetening; hydrogen sulfide removal from shale and coal processes, etc.), and in the manufacture of polymers and electronics, and may be found in pharmaceut
‘Long-term feeding effects of stevioside sweetener on some toxicological parameters of growing rats’
Autor:
Michael C. Carakostas
Publikováno v:
Journal of Applied Toxicology. 32:149-151
Publikováno v:
Regulatory Toxicology and Pharmacology. 23:49-54
Target animal safety studies are required for the regulatory approval of any new veterinary pharmaceutical registered almost anywhere in the world. Both the United States and Europe have extensive guidelines for conducting these studies. Due to new v
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 51
The safety of steviol glycoside sweeteners has been extensively reviewed in the literature. National and international food safety agencies and approximately 20 expert panels have concluded that steviol glycosides, including the widely used sweetener
Autor:
Chad M, Thompson, David W, Gaylor, J Andrew, Tachovsky, Camarie, Perry, Michael C, Carakostas, Laurie C, Haws
Publikováno v:
Journal of applied toxicology : JAT. 33(12)
Sulfolane is a widely used industrial solvent that is often used for gas treatment (sour gas sweetening; hydrogen sulfide removal from shale and coal processes, etc.), and in the manufacture of polymers and electronics, and may be found in pharmaceut
Publikováno v:
Fundamental and Applied Toxicology. 18:590-595
A blend of the hydrochlorofluorocarbon isomers HCFC-225ca and HCFC-225cb has been proposed as a potential substitute for CFC-113, an important solvent and cleaning agent. The toxicity following repeated inhalation of an HCFC-225 isomer mixture was as