Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Michael C. Byington"'
Publikováno v:
The Journal of Physical Chemistry B. 121:9091-9101
Protein condensates play essential roles in physiological processes and pathological conditions. Recently discovered mesoscopic protein-rich clusters may act as crucial precursors for the nucleation of ordered protein solids, such as crystals, sickle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93882b9ce7a15b432d415cb149ab4d26
https://doi.org/10.1021/acs.jpcb.7b05425
https://doi.org/10.1021/acs.jpcb.7b05425
Publikováno v:
Journal of Crystal Growth. 468:493-501
Shear flow alters the rate at which crystals nucleate from solution, yet the underlying mechanisms remain poorly understood. To fill this knowledge gap, we explore the response to shear of dense liquid clusters, which may serve as crystal nucleation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81e7e8d4edd2e979b41c399a9393ebc8
https://doi.org/10.1016/j.jcrysgro.2016.12.080
https://doi.org/10.1016/j.jcrysgro.2016.12.080
Autor:
Jacinta C. Conrad, Laurence A. Angel, Mohammad S. Safari, Vassiliy Lubchenko, David H. Hawke, Michael C. Byington, Peter G. Vekilov, Jacob W. McCabe
Protein crystallization is central to understanding of molecular structure in biology, a vital part of processes in the pharmaceutical industry, and a crucial component of numerous disease pathologies. Crystallization starts with nucleation and how n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d0b8a7a4597eaf41a96ba27ecf7e93f
Publikováno v:
The journal of physical chemistry letters. 7(13)
According to recently proposed two-step nucleation mechanisms, crystal nuclei form within preexisting dense liquid clusters. Clusters with radii about 100 nm, which capture from 10(-7) to 10(-3) of the total protein, have been observed with numerous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eee6240f35799e690b7dba0d1f9fc045
https://pubmed.ncbi.nlm.nih.gov/27267087
https://pubmed.ncbi.nlm.nih.gov/27267087